IN2015DN02376A - - Google Patents

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Publication number
IN2015DN02376A
IN2015DN02376A IN2376DEN2015A IN2015DN02376A IN 2015DN02376 A IN2015DN02376 A IN 2015DN02376A IN 2376DEN2015 A IN2376DEN2015 A IN 2376DEN2015A IN 2015DN02376 A IN2015DN02376 A IN 2015DN02376A
Authority
IN
India
Prior art keywords
crystal
luliconazole
plane
solubility
improving
Prior art date
Application number
Inventor
Takaaki; Masuda
Nohyaku Co Ltd Nihon
Original Assignee
Pola Pharma Inc
Nohyaku Co Ltd Nihon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Pharma Inc, Nohyaku Co Ltd Nihon filed Critical Pola Pharma Inc
Publication of IN2015DN02376A publication Critical patent/IN2015DN02376A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

An object is to provide means for improving the solubility of luliconazole. Disclosed is a crystal of luliconazole wherein the crystal has such a crystal habit that (021) plane is a specific crystal growth plane.
IN2376DEN2015 2012-09-14 2012-11-02 IN2015DN02376A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012202516 2012-09-14
PCT/JP2012/079050 WO2014041708A1 (en) 2012-09-14 2012-11-02 Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal

Publications (1)

Publication Number Publication Date
IN2015DN02376A true IN2015DN02376A (en) 2015-09-04

Family

ID=47278492

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2376DEN2015 IN2015DN02376A (en) 2012-09-14 2012-11-02

Country Status (7)

Country Link
US (1) US9199977B2 (en)
EP (1) EP2895479A1 (en)
JP (1) JP5453559B1 (en)
CN (1) CN104619703A (en)
IN (1) IN2015DN02376A (en)
RU (1) RU2603963C2 (en)
WO (1) WO2014041708A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9050271B2 (en) 2009-04-09 2015-06-09 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN102387785B (en) 2009-04-09 2017-08-25 宝丽制药股份有限公司 Antifungal medicine composition
CN102481286B (en) 2009-08-25 2014-02-26 宝丽制药股份有限公司 Antimycotic pharmaceutical composition
US8962669B2 (en) 2010-06-11 2015-02-24 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2014041846A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and phrmaceutical composition prepared by containing the crystal
RU2622644C2 (en) 2012-09-14 2017-06-19 Пола Фарма Инк. Crystalline substance and pharmaceutical preparation containing it
JP5460797B1 (en) 2012-09-14 2014-04-02 株式会社ポーラファルマ Amide derivatives and their use as stability indicators
JP5589110B1 (en) 2013-03-08 2014-09-10 株式会社ポーラファルマ Crystal having crystal habit and pharmaceutical composition containing the crystal as an active ingredient
JP5680161B1 (en) * 2013-09-06 2015-03-04 株式会社ポーラファルマ Crystal having crystal habit and pharmaceutical composition containing the crystal as an active ingredient
JP5587488B1 (en) 2013-12-12 2014-09-10 株式会社ポーラファルマ Evaluation method and index substance of preparation containing luliconazole
JP5951864B1 (en) * 2015-06-05 2016-07-13 株式会社ポーラファルマ Anti-giardia drugs
JP2017101009A (en) * 2015-12-04 2017-06-08 株式会社ポーラファルマ Anti-acanthamoeba agent and method for producing the same
JP6085706B1 (en) * 2016-03-31 2017-02-22 株式会社ポーラファルマ Anti-tritricomonas

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3081766B2 (en) 1994-05-06 2000-08-28 東興薬品工業株式会社 Keratin storage type antifungal external composition
JP3278738B2 (en) 1995-07-08 2002-04-30 日本農薬株式会社 Antifungal agent
CN1091596C (en) * 1995-07-08 2002-10-02 日本农药株式会社 Anti fungal agent, compound therefor, process for producing the same
JP2002114680A (en) 2000-07-31 2002-04-16 Nippon Nohyaku Co Ltd Antifungal agent
PL2005958T3 (en) 2006-03-08 2013-11-29 Nihon Nohyaku Co Ltd External pharmaceutical composition
AU2006339841B2 (en) * 2006-03-08 2012-08-30 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
US8058303B2 (en) 2006-03-08 2011-11-15 Nihon Nohyaku Co, Ltd Pharmaceutical composition for external use
KR20100068271A (en) 2007-09-05 2010-06-22 가부시키가이샤 폴라 파마 Antifungal pharmaceutical composition
EP2191827B1 (en) 2007-09-05 2013-10-30 Pola Pharma Inc. Antifungal composition
KR20100075475A (en) 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 Pharmaceutical composition
WO2010093992A1 (en) 2009-02-13 2010-08-19 Topica Pharmaceuticals, Inc Anti-fungal formulation
US9050271B2 (en) 2009-04-09 2015-06-09 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN102387785B (en) 2009-04-09 2017-08-25 宝丽制药股份有限公司 Antifungal medicine composition
CN102481286B (en) 2009-08-25 2014-02-26 宝丽制药股份有限公司 Antimycotic pharmaceutical composition
US8962669B2 (en) 2010-06-11 2015-02-24 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN103012385B (en) * 2012-02-17 2015-07-08 山东威智医药工业有限公司 Crystal form of luliconazole and preparation method thereof
IN2015DN02377A (en) 2012-09-14 2015-09-04 Pola Pharma Inc
WO2014041846A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and phrmaceutical composition prepared by containing the crystal
JP5460797B1 (en) 2012-09-14 2014-04-02 株式会社ポーラファルマ Amide derivatives and their use as stability indicators
RU2622644C2 (en) 2012-09-14 2017-06-19 Пола Фарма Инк. Crystalline substance and pharmaceutical preparation containing it
JP5589110B1 (en) 2013-03-08 2014-09-10 株式会社ポーラファルマ Crystal having crystal habit and pharmaceutical composition containing the crystal as an active ingredient

Also Published As

Publication number Publication date
WO2014041708A1 (en) 2014-03-20
JP5453559B1 (en) 2014-03-26
US20150183766A1 (en) 2015-07-02
EP2895479A1 (en) 2015-07-22
RU2015109127A (en) 2016-11-10
RU2603963C2 (en) 2016-12-10
JP2014074008A (en) 2014-04-24
US9199977B2 (en) 2015-12-01
CN104619703A (en) 2015-05-13

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