IN2015DN01454A - - Google Patents

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Publication number
IN2015DN01454A
IN2015DN01454A IN1454DEN2015A IN2015DN01454A IN 2015DN01454 A IN2015DN01454 A IN 2015DN01454A IN 1454DEN2015 A IN1454DEN2015 A IN 1454DEN2015A IN 2015DN01454 A IN2015DN01454 A IN 2015DN01454A
Authority
IN
India
Prior art keywords
drug
microneedle array
skin
quantitative
vaccine
Prior art date
Application number
Inventor
Masaki Ishibashi
Hidetoshi Hamamoto
Taishi Tanaka
Kazuteru Kouno
Kiyotsuna Toyohara
Original Assignee
Teijin Ltd
Medrx Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd, Medrx Co Ltd filed Critical Teijin Ltd
Publication of IN2015DN01454A publication Critical patent/IN2015DN01454A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/042—Force radial
    • F04C2270/0421—Controlled or regulated

Abstract

Provided is a microneedle array which enables the quantitative and accurate insertion of a drug into the skin. It is found that when a drug composition comprising a drug and an additive and having Vickers hardness of about 3 or more is applied to a microneedle array the unintended removal of the drug can be avoided and the drug can be surely inserted into the skin along with the microneedle array. Consequently the microneedle array coated with the drug composition according to the present invention can be used in the fields in which the drug is required to be administered with high quantitative performance even when the drug is contained at a low content e.g. the administration of a vaccine and the scope of application of the microneedle array can be extended.
IN1454DEN2015 2012-08-30 2013-08-30 IN2015DN01454A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012190693 2012-08-30
PCT/JP2013/073386 WO2014034882A1 (en) 2012-08-30 2013-08-30 Microneedle array coated with drug composition

Publications (1)

Publication Number Publication Date
IN2015DN01454A true IN2015DN01454A (en) 2015-07-03

Family

ID=50183686

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1454DEN2015 IN2015DN01454A (en) 2012-08-30 2013-08-30

Country Status (12)

Country Link
US (1) US10556098B2 (en)
EP (1) EP2891506A1 (en)
JP (2) JPWO2014034882A1 (en)
KR (1) KR20150052092A (en)
CN (1) CN104602752A (en)
AU (1) AU2013309944A1 (en)
CA (1) CA2882275A1 (en)
HK (1) HK1209657A1 (en)
IN (1) IN2015DN01454A (en)
MX (1) MX2015002205A (en)
RU (1) RU2015111197A (en)
WO (1) WO2014034882A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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WO2015066819A1 (en) 2013-11-08 2015-05-14 Carlos Filipe Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions
CN105126242A (en) * 2015-07-26 2015-12-09 北京化工大学 Polymer coating microneedle patch convenient for antibiotic skin testing and preparation method thereof
WO2017135290A1 (en) * 2016-02-03 2017-08-10 コスメディ製薬株式会社 Coating liquid for microneedles, microneedle-coating substance, and microneedle array
US11266344B2 (en) 2016-09-21 2022-03-08 Samsung Electronics Co., Ltd. Method for measuring skin condition and electronic device therefor
US11690799B2 (en) 2018-04-19 2023-07-04 Lts Lohmann Therapie-Systeme Ag Microneedle system for applying interferon
KR102031062B1 (en) * 2019-02-18 2019-10-11 주식회사 테라젝아시아 Kit for injecting drugs
KR102221222B1 (en) * 2019-06-28 2021-03-03 (주)카이로스 Patch with needles and method for manufacturing the same
FR3117775B1 (en) * 2020-12-18 2024-04-19 Commissariat A Lenergie Atomique Et Aux Energies Alternatives PHARMACEUTICAL PRODUCT, ITS PREPARATION PROCESS AND ITS USES
CN112779516B (en) * 2020-12-22 2024-03-08 苏州恒之清生物科技有限公司 Crystal silicon microneedle with hard coating protection and preparation method thereof

Family Cites Families (24)

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GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
JP2006500974A (en) * 2002-06-28 2006-01-12 アルザ・コーポレーシヨン Transdermal drug delivery device with coated microprojections
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20090017210A1 (en) * 2007-07-09 2009-01-15 Andrianov Alexander K Methods and systems for coating a microneedle with a dosage of a biologically active compound
US20100221314A1 (en) 2007-10-18 2010-09-02 Hisamitsu Pharmaceutical Co., Inc. Microneedle Device
EP2231257A4 (en) * 2007-12-24 2013-11-06 Univ Queensland Coating method
US7704098B2 (en) * 2008-07-22 2010-04-27 Amphenol Corporation Registered jack with enhanced EMI protection
US7969673B2 (en) 2008-11-11 2011-06-28 Phokus Research Group, Llc Night vision instrument focus device
EP2383013A4 (en) 2008-12-26 2012-11-28 Hisamitsu Pharmaceutical Co Microneedle device
EP2392378B1 (en) * 2009-01-30 2017-03-15 Hisamitsu Pharmaceutical Co., Inc. Microneedle device
JP5615814B2 (en) * 2009-06-10 2014-10-29 久光製薬株式会社 Microneedle device
US8911422B2 (en) * 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
WO2011105508A1 (en) * 2010-02-24 2011-09-01 久光製薬株式会社 Micro-needle device and preparation method
WO2011116388A1 (en) * 2010-03-19 2011-09-22 Nanostar Health Corporation Body fluid sampling/fluid delivery device
US8940799B2 (en) 2010-03-25 2015-01-27 Medtronic Xomed, Inc. Adjusting drug loading in polymeric materials
EP2575845B1 (en) * 2010-05-28 2017-02-15 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays
ES2531577T3 (en) * 2010-08-20 2015-03-17 Novartis Ag Needle sets for administration of soluble flu vaccine
AU2011321343A1 (en) * 2010-10-25 2013-05-23 Medrx Co., Ltd. Microneedle
EP2633879A4 (en) 2010-10-27 2014-04-09 Medrx Co Ltd Micro-needle coating method
WO2012057602A1 (en) 2010-10-29 2012-05-03 Hian Khim Francis Then Intravenous fluid delivery system
JP6033280B2 (en) * 2011-04-22 2016-11-30 ラジウス ヘルス，インコーポレイテッド Drug delivery method for PTH, PTHrP, and related peptides
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KR20150003745A (en) * 2012-04-25 2015-01-09 데이진 가부시키가이샤 Microneedle and microneedle array

Also Published As

Publication number Publication date
RU2015111197A (en) 2016-10-20
US20150216796A1 (en) 2015-08-06
EP2891506A1 (en) 2015-07-08
HK1209657A1 (en) 2016-04-08
AU2013309944A1 (en) 2015-03-05
JP2021072884A (en) 2021-05-13
US10556098B2 (en) 2020-02-11
CA2882275A1 (en) 2014-03-06
MX2015002205A (en) 2015-05-08
KR20150052092A (en) 2015-05-13
WO2014034882A1 (en) 2014-03-06
CN104602752A (en) 2015-05-06
JPWO2014034882A1 (en) 2016-08-08

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