IN2015DN01068A - - Google Patents

Info

Publication number
IN2015DN01068A
IN2015DN01068A IN1068DEN2015A IN2015DN01068A IN 2015DN01068 A IN2015DN01068 A IN 2015DN01068A IN 1068DEN2015 A IN1068DEN2015 A IN 1068DEN2015A IN 2015DN01068 A IN2015DN01068 A IN 2015DN01068A
Authority
IN
India
Prior art keywords
drug eluting
surgical screw
driver
drive recess
disposed
Prior art date
Application number
Inventor
David Armbruster
Anurag Pandey
Original Assignee
Synthes Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes Gmbh filed Critical Synthes Gmbh
Publication of IN2015DN01068A publication Critical patent/IN2015DN01068A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/8605Heads, i.e. proximal ends projecting from bone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/8605Heads, i.e. proximal ends projecting from bone
    • A61B17/861Heads, i.e. proximal ends projecting from bone specially shaped for gripping driver
    • A61B17/8615Heads, i.e. proximal ends projecting from bone specially shaped for gripping driver at the central region of the screw head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/864Pins or screws or threaded wires; nuts therefor hollow, e.g. with socket or cannulated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/866Material or manufacture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069Devices for implanting pellets, e.g. markers or solid medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/8685Pins or screws or threaded wires; nuts therefor comprising multiple separate parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004(bio)absorbable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00889Material properties antimicrobial, disinfectant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00893Material properties pharmaceutically effective
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B2017/561Implants with special means for releasing a drug

Abstract

The present invention provides a drug eluting surgical screw and a method for manufacturing a drug eluting surgical screw. The drug eluting surgical screw may include a shaft having a threaded portion a head having a drive recess disposed at a proximal end of the shaft the drive recess having a reservoir region and a driver engagement region and at least one or more drug eluting components disposed within the reservoir region of the drive recess in a manner that does not substantially impair a connection between a driver and the surgical screw when the driver is operably disposed within the driver engagement region each of the at least one or more drug eluting components including a carrier matrix and a therapeutic agent the therapeutic agent being at least 20 wt% of the drug eluting component prior to any implantation of the drug eluting surgical screw.
IN1068DEN2015 2012-08-15 2013-08-13 IN2015DN01068A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261683262P 2012-08-15 2012-08-15
PCT/US2013/054671 WO2014028449A1 (en) 2012-08-15 2013-08-13 Drug eluting surgical screw

Publications (1)

Publication Number Publication Date
IN2015DN01068A true IN2015DN01068A (en) 2015-06-26

Family

ID=49004048

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1068DEN2015 IN2015DN01068A (en) 2012-08-15 2013-08-13

Country Status (9)

Country Link
US (4) US9364273B2 (en)
EP (2) EP3308727B1 (en)
JP (1) JP6312677B2 (en)
KR (1) KR102191658B1 (en)
CN (1) CN104582612B (en)
CA (1) CA2882284C (en)
IN (1) IN2015DN01068A (en)
TW (1) TWI613991B (en)
WO (1) WO2014028449A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9364273B2 (en) 2012-08-15 2016-06-14 DePuy Synthes Products, Inc. Drug eluting surgical screw
US10537373B2 (en) * 2015-04-24 2020-01-21 Biomet Sports Medicine, Llc Porous implants with injectable capabilities
EP3419715B1 (en) * 2016-02-26 2021-09-15 Neuronano AB Method of implantation of cell aggregates and tissue fragments
EP3424450B1 (en) * 2016-02-29 2021-02-17 Medtronic Sofamor Danek, Co., Ltd. Set screw for antibacterial device to be implanted in vivo
KR20240015057A (en) * 2021-01-15 2024-02-02 디퓨전 알엑스 인코포레이티드 Joint implant that continuously and continuously releases therapeutic agents

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2843963A1 (en) * 1978-10-09 1980-04-24 Merck Patent Gmbh BODY-RESORBABLE SHAPED MATERIAL BASED ON COLLAGEN AND THEIR USE IN MEDICINE
WO1981002667A1 (en) * 1980-03-27 1981-10-01 Nat Res Dev Antimicrobial surgical implants
JPS5770816A (en) * 1980-10-17 1982-05-01 Ono Pharmaceut Co Ltd Multilayered film preparation of prostagladin of prolonged action
US4905680A (en) * 1986-10-27 1990-03-06 Johnson & Johnson Orthopaedics, Inc. Absorbable bone plate
US5387419A (en) * 1988-03-31 1995-02-07 The University Of Michigan System for controlled release of antiarrhythmic agents
US5985317A (en) * 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
TW402930U (en) * 1999-02-12 2000-08-21 Yang Je Jung Improvement of marrow internal nail structure
EP1330270A2 (en) 2000-11-03 2003-07-30 Control Delivery Systems, Inc. Sustained release device for treating conditions of the joint
US20050203612A1 (en) * 2000-12-22 2005-09-15 Avantec Vascular Corporation Devices delivering therapeutic agents and methods regarding the same
US7235079B2 (en) * 2004-11-18 2007-06-26 Acumed Llc Composite bone fasteners
CA2477558A1 (en) * 2002-02-28 2003-09-04 Novartis Ag N-{5-[4-(4-methyl-piperazino-methyl)­-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine coated stents
US7220755B2 (en) * 2003-11-12 2007-05-22 Biosensors International Group, Ltd. 42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
WO2005070333A1 (en) * 2004-01-13 2005-08-04 Orthobiologica, Inc. Drug delivery to a joint
US20050250838A1 (en) * 2004-05-04 2005-11-10 Challapalli Prasad V Formulation for sustained delivery
US8535357B2 (en) * 2004-12-09 2013-09-17 Biomet Sports Medicine, Llc Continuous phase compositions for ACL repair
US7909826B2 (en) * 2005-03-24 2011-03-22 Depuy Spine, Inc. Low profile spinal tethering methods
US9247973B2 (en) * 2007-09-28 2016-02-02 DePuy Synthes Products, Inc. Anti-microbial implant
US20090163919A1 (en) 2007-12-19 2009-06-25 Peter Tarcha Devices, systems, and methods for delivery of a pharmaceutical to a subject's spine
JP5774989B2 (en) * 2008-08-13 2015-09-09 スメド−ティーエイ/ティーディー・エルエルシー Orthopedic screw
US20100249783A1 (en) * 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Drug-eluting implant cover
CA2797110C (en) 2010-04-22 2020-07-21 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
US9211175B2 (en) * 2010-07-08 2015-12-15 Covidien Lp Self-detachable medical devices
US20120109111A1 (en) * 2010-10-29 2012-05-03 Empire Technology Development Llc Fenestration system
US9364273B2 (en) 2012-08-15 2016-06-14 DePuy Synthes Products, Inc. Drug eluting surgical screw
US10307194B2 (en) * 2017-08-01 2019-06-04 Warsaw Orthopedic, Inc. Spinal implant and method of manufacture

Also Published As

Publication number Publication date
US20180070998A1 (en) 2018-03-15
US11039870B2 (en) 2021-06-22
EP2884927B1 (en) 2017-09-27
US20190167325A1 (en) 2019-06-06
TW201427638A (en) 2014-07-16
US20140052060A1 (en) 2014-02-20
KR102191658B1 (en) 2020-12-18
EP3308727B1 (en) 2020-07-22
JP2015530904A (en) 2015-10-29
US9833271B2 (en) 2017-12-05
US20160278831A1 (en) 2016-09-29
TWI613991B (en) 2018-02-11
KR20150043385A (en) 2015-04-22
JP6312677B2 (en) 2018-04-18
EP2884927A1 (en) 2015-06-24
CA2882284C (en) 2020-12-15
US9364273B2 (en) 2016-06-14
WO2014028449A1 (en) 2014-02-20
CN104582612B (en) 2019-07-05
US10226293B2 (en) 2019-03-12
EP3308727A1 (en) 2018-04-18
BR112015003305A2 (en) 2017-07-04
CN104582612A (en) 2015-04-29
CA2882284A1 (en) 2014-02-20

Similar Documents

Publication Publication Date Title
MX2018000915A (en) Dose control device for injectable-drug delivery devices.
IN2015DN01068A (en)
WO2016113357A8 (en) Proteasome inhibitors for treating a disorder related to an accumulation of non-degraded abnormal protein or a cancer
MX363178B (en) Galactose-pronged carbohydrate compounds for the treatment of diabetic nephropathy and associated disorders.
PH12014501693A1 (en) Antimicrobial compositions comprising dgla, 15-ohepa and/or 15-hetre and methods of use thereof
BR112014010803A2 (en) treatment method
IN2015DN03219A (en)
WO2015051543A8 (en) Cancer treatment with combination of plinabulin and taxane
NZ713029A (en) Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith
MX2016006587A (en) Anchor having a controlled driver orientation.
IN2015DN01479A (en)
WO2015015378A3 (en) Heterobicycloaryl rorc2 inhibitors and methods of use thereof
EP2560633A4 (en) Intravenous omega-3 fatty acid compositions & method of use
WO2012112340A3 (en) Methods and compositions for treating, reducing, or preventing damage to the nervous system of animals
WO2014130691A3 (en) Pharmaceutical formulations of nitrite and uses thereof
EA033212B1 (en) Pen for the treatment of dermatological disorders and method for use thereof
NZ598171A (en) Methods and compositions for treating thyroid-related medical conditions with reduced folates
MX2017000764A (en) Aqueous formulation comprising paracetamol and ibuprofen.
UA95708U (en) Screw implant
WO2016134257A8 (en) Oxabicycloheptanes and oxabicycloheptenes for the treatment of depressive and stress disorders
WO2014071168A3 (en) Administering inhibitors of tgfbeta signaling to improve muscle function in cancer patients
PH12017500988A1 (en) Calcitonin analogues for treating diseases and disorders
NZ627684A (en) Bone screw and method for manufacturing the same
WO2014026013A3 (en) Methods for maintaining or improving health, well-being and/or a physiological function in a subject
MX2015012455A (en) Method for the treatment of fatty liver disease.