IN2014MU01178AIN1178MU2014AIN2014MU01178AIN 2014MU01178 AIN2014MU01178 AIN 2014MU01178AIN 1178MU2014 AIN1178MU2014 AIN 1178MU2014AIN 2014MU01178 AIN2014MU01178 AIN 2014MU01178A
Authority
IN
India
Prior art keywords
salts
methyldopa
relates
present
oral bioavailability
Prior art date
Application number
Inventor
Pankaj Trimbak Adsare
Vijay Suggala
Kapileswar Swain
Yatendra Kumar
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt LtdfiledCriticalWockhardt Ltd
Priority to PCT/IB2015/052016priorityCriticalpatent/WO2015150959A1/en
Priority to IN1178MU2014prioritypatent/IN2014MU01178A/en
Publication of IN2014MU01178ApublicationCriticalpatent/IN2014MU01178A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Medicinal Preparation
(AREA)
Abstract
The present invention relates to process for preparing a stable oral liquid pharmaceutical composition comprising methyldopa or salts thereof with enhanced oral bioavailability. In particular, the present invention relates to a pharmaceutical compositions prepared into a soft gelatin capsule containing methyldopa or salts thereof as the active ingredient with enhanced oral bioavailability. There is also provided a method of use of such composition in the treatment of hypertension.