IN2014MU00815A - - Google Patents
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- Publication number
- IN2014MU00815A IN2014MU00815A IN815MU2014A IN2014MU00815A IN 2014MU00815 A IN2014MU00815 A IN 2014MU00815A IN 815MU2014 A IN815MU2014 A IN 815MU2014A IN 2014MU00815 A IN2014MU00815 A IN 2014MU00815A
- Authority
- IN
- India
- Prior art keywords
- stem cells
- cancer stem
- compositions
- methods
- proliferation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
The present invention provides compounds of formula (I), compositions, uses thereof and methods for inhibiting proliferation or obliterating cancer stem cells which includes killing; and/or inducing apoptosis in cancer stem cells. Included within the scope of such compounds, compositions, uses thereof and methods are those in which proliferation of cancer stem cells are selectively eradicated or inhibited. I
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/125,323 US20180169100A1 (en) | 2014-03-11 | 2015-03-11 | Cancer Stem Cell Targeting Compounds |
EP15761397.7A EP3116867A4 (en) | 2014-03-11 | 2015-03-11 | Cancer stem cell targeting compounds |
MX2016011675A MX2016011675A (en) | 2014-03-11 | 2015-03-11 | Cancer stem cell targeting compounds. |
AU2015228386A AU2015228386A1 (en) | 2014-03-11 | 2015-03-11 | Cancer stem cell targeting compounds |
PCT/IN2015/050020 WO2015136557A2 (en) | 2014-03-11 | 2015-03-11 | Cancer stem cell targeting compounds |
CA2941703A CA2941703A1 (en) | 2014-03-11 | 2015-03-11 | Cancer stem cell targeting compounds |
JP2016556878A JP2017507969A (en) | 2014-03-11 | 2015-03-11 | Cancer stem cell target compound |
IN815MU2014 IN2014MU00815A (en) | 2014-03-11 | 2015-03-11 | |
IL247723A IL247723A0 (en) | 2014-03-11 | 2016-09-08 | Cancer stem cell targeting compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN815MU2014 IN2014MU00815A (en) | 2014-03-11 | 2015-03-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014MU00815A true IN2014MU00815A (en) | 2015-09-25 |
Family
ID=54072550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN815MU2014 IN2014MU00815A (en) | 2014-03-11 | 2015-03-11 |
Country Status (9)
Country | Link |
---|---|
US (1) | US20180169100A1 (en) |
EP (1) | EP3116867A4 (en) |
JP (1) | JP2017507969A (en) |
AU (1) | AU2015228386A1 (en) |
CA (1) | CA2941703A1 (en) |
IL (1) | IL247723A0 (en) |
IN (1) | IN2014MU00815A (en) |
MX (1) | MX2016011675A (en) |
WO (1) | WO2015136557A2 (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4783731B2 (en) * | 2003-08-29 | 2011-09-28 | ヴァーナリス(ケンブリッジ)リミテッド | Pyrimidothiophene compound |
GB0416168D0 (en) * | 2004-07-20 | 2004-08-18 | Vernalis Cambridge Ltd | Pyrmidothiophene compounds |
US20100227853A1 (en) * | 2008-04-18 | 2010-09-09 | Trustees Of Boston College | Inhibitors of cyclic amp phosphodiesterases |
ES2363358B1 (en) * | 2009-04-03 | 2012-06-21 | FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al | THERAPEUTIC AGENTS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AN INDESEABLE CELLULAR PROLIFERATION. |
CN102984941B (en) * | 2009-09-04 | 2016-08-17 | 密执安大学评议会 | For treating leukemic compositions and method |
-
2015
- 2015-03-11 CA CA2941703A patent/CA2941703A1/en not_active Abandoned
- 2015-03-11 WO PCT/IN2015/050020 patent/WO2015136557A2/en active Application Filing
- 2015-03-11 JP JP2016556878A patent/JP2017507969A/en active Pending
- 2015-03-11 IN IN815MU2014 patent/IN2014MU00815A/en unknown
- 2015-03-11 US US15/125,323 patent/US20180169100A1/en not_active Abandoned
- 2015-03-11 MX MX2016011675A patent/MX2016011675A/en unknown
- 2015-03-11 AU AU2015228386A patent/AU2015228386A1/en not_active Abandoned
- 2015-03-11 EP EP15761397.7A patent/EP3116867A4/en not_active Withdrawn
-
2016
- 2016-09-08 IL IL247723A patent/IL247723A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3116867A4 (en) | 2017-10-18 |
WO2015136557A3 (en) | 2015-11-12 |
WO2015136557A9 (en) | 2022-05-27 |
EP3116867A2 (en) | 2017-01-18 |
US20180169100A1 (en) | 2018-06-21 |
IL247723A0 (en) | 2016-11-30 |
JP2017507969A (en) | 2017-03-23 |
AU2015228386A1 (en) | 2016-09-22 |
CA2941703A1 (en) | 2015-09-17 |
MX2016011675A (en) | 2016-12-14 |
WO2015136557A2 (en) | 2015-09-17 |
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