IN2014MU00186AIN186MU2014AIN2014MU00186AIN 2014MU00186 AIN2014MU00186 AIN 2014MU00186AIN 186MU2014 AIN186MU2014 AIN 186MU2014AIN 2014MU00186 AIN2014MU00186 AIN 2014MU00186A
Authority
IN
India
Prior art keywords
linagliptin
metformin
pharmaceutical composition
relates
salt
Prior art date
Application number
Inventor
Venkataramana Naidu
Balasaheb Parshuram Wagh
Mohan L Krishna
Girish Kumar Jain
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt LtdfiledCriticalWockhardt Ltd
Priority to IN186MU2014priorityCriticalpatent/IN2014MU00186A/en
Priority to PCT/IB2015/050453prioritypatent/WO2015110962A1/en
Publication of IN2014MU00186ApublicationCriticalpatent/IN2014MU00186A/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
The present invention relates to a process of preparing a pharmaceutical composition of metformin and linagliptin or salt thereof. In particular, the present invention relates to a process of preparing stable oral pharmaceutical composition comprising fixed dose combination of metformin and linagliptin or salt thereof. By using an amino sugar, it is possible to achieve the stable pharmaceutical composition of metformin and linagliptin. The invention further relates to use of such composition in the treatment of diabetes mellitus.
C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same.