IN2014MN02555A - - Google Patents
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- Publication number
- IN2014MN02555A IN2014MN02555A IN2555MUN2014A IN2014MN02555A IN 2014MN02555 A IN2014MN02555 A IN 2014MN02555A IN 2555MUN2014 A IN2555MUN2014 A IN 2555MUN2014A IN 2014MN02555 A IN2014MN02555 A IN 2014MN02555A
- Authority
- IN
- India
- Prior art keywords
- well
- bottom plate
- interest
- single cells
- individual
- Prior art date
Links
- 239000012530 fluid Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/088—Microfluidic devices comprising semi-permeable flat membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0039—Inorganic membrane manufacture
- B01D67/0053—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes
- B01D67/006—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods
- B01D67/0062—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods by micromachining techniques, e.g. using masking and etching steps, photolithography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/02—Inorganic material
- B01D71/0215—Silicon carbide; Silicon nitride; Silicon oxycarbide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
- B01L3/50255—Multi-well filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0851—Bottom walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
- G01N2001/288—Filter punches
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Inorganic Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Optics & Photonics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A micro well plate is described for capturing and distributing single cells in individual wells is described wherein at least one individual well is provided with a bottom plate having at least one pore to pass sample liquid such that if one object or cell of interest is collected on the bottom plate of the well the sample flow rate through that particular well is significantly reduced minimizing the possibility that multiple cells or objects of interest entering the same well. The presented invention is particularly suited for obtaining single cells and/or microorganisms suspended in fluid samples for subsequent detailed interrogation.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1039638A NL1039638C2 (en) | 2012-06-01 | 2012-06-01 | Diagnostic device with a filtration membrane for on spot microscopic diagnostic analysis and methods. |
NL1040089A NL1040089C2 (en) | 2013-03-12 | 2013-03-12 | Micro well plate to distribute single cells in single wells, and methods to use such plate. |
PCT/NL2013/050389 WO2013180567A2 (en) | 2012-06-01 | 2013-05-29 | A microsieve diagnostic device in the isolation and analysis of single cells |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014MN02555A true IN2014MN02555A (en) | 2015-07-24 |
Family
ID=48672779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN2555MUN2014 IN2014MN02555A (en) | 2012-06-01 | 2013-05-29 |
Country Status (4)
Country | Link |
---|---|
US (1) | US9638636B2 (en) |
EP (2) | EP3725409A1 (en) |
IN (1) | IN2014MN02555A (en) |
WO (1) | WO2013180567A2 (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013019491A1 (en) | 2011-08-01 | 2013-02-07 | Denovo Sciences | Cell capture system and method of use |
US9404864B2 (en) | 2013-03-13 | 2016-08-02 | Denovo Sciences, Inc. | System for imaging captured cells |
US10466160B2 (en) | 2011-08-01 | 2019-11-05 | Celsee Diagnostics, Inc. | System and method for retrieving and analyzing particles |
US10816550B2 (en) | 2012-10-15 | 2020-10-27 | Nanocellect Biomedical, Inc. | Systems, apparatus, and methods for sorting particles |
US9707562B2 (en) | 2013-03-13 | 2017-07-18 | Denovo Sciences, Inc. | System for capturing and analyzing cells |
US10391490B2 (en) | 2013-05-31 | 2019-08-27 | Celsee Diagnostics, Inc. | System and method for isolating and analyzing cells |
WO2015118551A1 (en) * | 2014-02-10 | 2015-08-13 | Technion Research & Development Foundation Limited. | Method and apparatus for cell isolation, growth, replication, manipulation, and analysis |
JP2017518752A (en) | 2014-06-12 | 2017-07-13 | ウエハージェン インコーポレイテッド | Single cell capture using a capture polymer membrane |
US9757707B2 (en) | 2014-06-12 | 2017-09-12 | Takara Bio Usa, Inc. | Single cell capture with capture chips |
GB201501907D0 (en) * | 2015-02-05 | 2015-03-25 | Technion Res & Dev Foundation | System and method for single cell genetic analysis |
AU2016297895B2 (en) * | 2015-07-24 | 2021-04-22 | Novel Microdevices, Inc. | Sample extraction device and methods of use thereof |
JP7129909B2 (en) * | 2016-02-18 | 2022-09-02 | オプトフルイディクス インコーポレイテッド | Systems and methods for characterizing particles in fluid samples |
US11035795B2 (en) | 2016-02-18 | 2021-06-15 | Optofluidics, Inc. | Methods for identification of particles in a fluid sample |
EP3472351B1 (en) | 2016-06-15 | 2020-10-28 | Ludwig-Maximilians-Universität München | Single molecule detection or quantification using dna nanotechnology |
ES2860474T3 (en) | 2016-12-12 | 2021-10-05 | Minq Solutions B V | A procedure for conducting an assay |
US20200016591A1 (en) | 2016-12-15 | 2020-01-16 | University Of Twente | A Molecule Printing Device for the Analysis of the Secretome of Single Cells |
EP3609619A1 (en) | 2017-04-14 | 2020-02-19 | University Of Twente | Device and method for the continuous trapping of circulating tumor cells |
US10391493B2 (en) | 2017-08-29 | 2019-08-27 | Celsee Diagnostics, Inc. | System and method for isolating and analyzing cells |
KR102056938B1 (en) * | 2018-01-26 | 2019-12-17 | (주)메타포어 | Membrane structure with matrix structure and biomolecule filter using the same |
JP7045924B2 (en) | 2018-05-11 | 2022-04-01 | 東京応化工業株式会社 | Cell capture filter membrane and its use |
US11161066B2 (en) | 2018-09-13 | 2021-11-02 | International Business Machines Corporation | Micro-machined filter for magnetic particles |
WO2020090856A1 (en) | 2018-11-02 | 2020-05-07 | 東京応化工業株式会社 | Particle capturing device and particle capturing method |
KR102224065B1 (en) * | 2018-12-28 | 2021-03-05 | 포항공과대학교 산학협력단 | Porous microwell and membrane with the porous microwell, and method for manufacturing the same |
DE102019101389B4 (en) | 2019-01-21 | 2020-08-06 | Bruker Daltonik Gmbh | Process for sample preparation on a spectrometric sample carrier |
US10633693B1 (en) | 2019-04-16 | 2020-04-28 | Celsee Diagnostics, Inc. | System and method for leakage control in a particle capture system |
US11273439B2 (en) | 2019-05-07 | 2022-03-15 | Bio-Rad Laboratories, Inc. | System and method for target material retrieval from microwells |
SG11202112151UA (en) * | 2019-05-07 | 2021-12-30 | Bio Rad Laboratories | System and method for automated single cell processing |
US11724256B2 (en) | 2019-06-14 | 2023-08-15 | Bio-Rad Laboratories, Inc. | System and method for automated single cell processing and analyses |
US11767498B2 (en) * | 2019-08-28 | 2023-09-26 | Massachusetts Institute Of Technology | In vitro tissue plate |
WO2024011205A1 (en) * | 2022-07-08 | 2024-01-11 | Allegheny Singer Research Institute | Devices and methods for separating cells or cell fragments |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849077A (en) * | 1984-08-06 | 1989-07-18 | Akademie Der Wissenschaften Der Ddr | Process for solid phase-sequencing of nucleic acid fragments |
AU3752195A (en) * | 1994-10-07 | 1996-05-02 | Flinders Technologies Pty Ltd | Apparatus and method for storage, purification or reaction and processing of a biopolymer |
US20040053322A1 (en) * | 2000-01-31 | 2004-03-18 | Mcdevitt John T. | System and method for the analysis of bodily fluids |
US20060029955A1 (en) * | 2001-03-24 | 2006-02-09 | Antonio Guia | High-density ion transport measurement biochip devices and methods |
US20050009004A1 (en) * | 2002-05-04 | 2005-01-13 | Jia Xu | Apparatus including ion transport detecting structures and methods of use |
US7718442B2 (en) * | 2002-11-22 | 2010-05-18 | Genvault Corporation | Sealed sample storage element system and method |
US7597936B2 (en) * | 2002-11-26 | 2009-10-06 | University Of Utah Research Foundation | Method of producing a pigmented composite microporous material |
US7501279B2 (en) * | 2003-04-03 | 2009-03-10 | University Of Washington | Microwell arrays with nanoholes |
AU2004235238A1 (en) * | 2003-04-25 | 2004-11-11 | Jsr Corporation | Biochip and biochip kit, and method of producing the same and method of using the same |
CA2768779A1 (en) * | 2009-07-20 | 2011-01-27 | Siloam Biosciences, Inc. | Microfluidic assay platforms |
US8689649B2 (en) * | 2009-12-04 | 2014-04-08 | General Electric Company | Methods and systems to prevent punch loss during automated sample processing |
NL1038359C2 (en) * | 2010-03-31 | 2012-06-27 | Aquamarijn Res B V | Device and method for separation of circulating tumor cells. |
-
2013
- 2013-05-29 IN IN2555MUN2014 patent/IN2014MN02555A/en unknown
- 2013-05-29 WO PCT/NL2013/050389 patent/WO2013180567A2/en active Application Filing
- 2013-05-29 US US14/404,577 patent/US9638636B2/en active Active
- 2013-05-29 EP EP20172281.6A patent/EP3725409A1/en active Pending
- 2013-05-29 EP EP13730950.6A patent/EP2855020A2/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2855020A2 (en) | 2015-04-08 |
EP3725409A1 (en) | 2020-10-21 |
WO2013180567A3 (en) | 2014-04-10 |
US9638636B2 (en) | 2017-05-02 |
US20150160135A1 (en) | 2015-06-11 |
WO2013180567A2 (en) | 2013-12-05 |
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