IN2014MN02116A - - Google Patents

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Publication number
IN2014MN02116A
IN2014MN02116A IN2116MUN2014A IN2014MN02116A IN 2014MN02116 A IN2014MN02116 A IN 2014MN02116A IN 2116MUN2014 A IN2116MUN2014 A IN 2116MUN2014A IN 2014MN02116 A IN2014MN02116 A IN 2014MN02116A
Authority
IN
India
Prior art keywords
solid composition
ethylbicyclo
hept
proving
aminomethyl
Prior art date
Application number
Inventor
TAJIRIShinichiro
Masami Takemura
YOSHINAGAShinji
Original Assignee
Daiichi Sankyo Companyltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Companyltd filed Critical Daiichi Sankyo Companyltd
Publication of IN2014MN02116A publication Critical patent/IN2014MN02116A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention addresses the problem of proving a stabilized solid composition of an amino carboxylate salt. The solution is a medicinal solid composition containing [(1R 5S 6S) 6 (aminomethyl) 3 ethylbicyclo[3.2.0]hept 3 en 6 yl] acetic acid benzene sulfonate which is a compound having the formula (I) and appropriate additives.
IN2116MUN2014 2013-04-04 2014-04-03 IN2014MN02116A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013079006 2013-04-04
PCT/JP2014/059812 WO2014163132A1 (en) 2013-04-04 2014-04-03 Solid composition of amino carboxylate salt

Publications (1)

Publication Number Publication Date
IN2014MN02116A true IN2014MN02116A (en) 2015-09-04

Family

ID=51658423

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2116MUN2014 IN2014MN02116A (en) 2013-04-04 2014-04-03

Country Status (12)

Country Link
US (1) US9675570B2 (en)
EP (1) EP2826477B1 (en)
JP (1) JP5627062B1 (en)
KR (1) KR102142257B1 (en)
CN (1) CN104334169B (en)
BR (1) BR112014029538B1 (en)
CA (1) CA2870675C (en)
ES (1) ES2638420T3 (en)
HK (1) HK1204559A1 (en)
IN (1) IN2014MN02116A (en)
TW (1) TWI645863B (en)
WO (1) WO2014163132A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016148263A1 (en) * 2015-03-19 2016-09-22 第一三共株式会社 Solid preparation containing antioxidant agent
JP6630344B2 (en) * 2015-03-19 2020-01-15 第一三共株式会社 Solid preparation containing colorant
FR3075662B1 (en) * 2017-12-21 2022-06-24 Ifp Energies Now PRE-TREATMENT METHOD FOR IMPROVING THE FILLING OF AN ENCLOSURE WITH SOLID PARTICLES
JP7312751B2 (en) * 2018-07-30 2023-07-21 第一三共株式会社 Solid formulations of pharmaceuticals containing stabilizers
WO2021132072A1 (en) 2019-12-23 2021-07-01 第一三共株式会社 Film-coated tablets having smooth surface
CN115803020A (en) * 2020-07-27 2023-03-14 第一三共株式会社 Orally disintegrating tablet containing milobalin besylate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928183A1 (en) * 1989-08-25 1991-02-28 Goedecke Ag LACTAM-FREE CYCLIC AMINO ACIDS
JPH11189547A (en) * 1997-12-26 1999-07-13 Taisho Pharmaceut Co Ltd Stabilized nicorandil medicines and production of the same
JP2001064177A (en) * 1999-08-16 2001-03-13 Schering Ag Pharmaceutical preparation including benzamide derivative as ingredient
WO2006056874A1 (en) 2004-11-25 2006-06-01 Pfizer Limited Salt form
GB0425955D0 (en) * 2004-11-25 2004-12-29 Pfizer Ltd Salt form
JP4691434B2 (en) * 2005-11-08 2011-06-01 東和薬品株式会社 Stabilized cabergoline solid formulation
EP2192109B1 (en) * 2007-09-28 2013-09-04 Daiichi Sankyo Company, Limited Bicyclic -amino acid derivative
US8895141B2 (en) * 2008-08-18 2014-11-25 Mitsubishi Shoji Foodtech Co., Ltd. Excipient for compressed tablets comprising novel spherical mannitol
JP2010241796A (en) * 2009-03-17 2010-10-28 Daiichi Sankyo Co Ltd PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC gamma-AMINO ACID DERIVATIVE
JP5557292B2 (en) * 2009-03-26 2014-07-23 第一三共株式会社 Method for producing bicyclic γ-amino acid derivative
JP5674666B2 (en) * 2009-08-11 2015-02-25 富士化学工業株式会社 Disintegrating particle composition and intraoral quick disintegrating tablet

Also Published As

Publication number Publication date
HK1204559A1 (en) 2015-11-27
KR102142257B1 (en) 2020-08-07
US9675570B2 (en) 2017-06-13
EP2826477B1 (en) 2017-05-31
CN104334169A (en) 2015-02-04
TW201517932A (en) 2015-05-16
CA2870675A1 (en) 2014-10-09
ES2638420T3 (en) 2017-10-20
JPWO2014163132A1 (en) 2017-02-16
JP5627062B1 (en) 2014-11-19
KR20150138800A (en) 2015-12-10
CA2870675C (en) 2017-03-28
TWI645863B (en) 2019-01-01
BR112014029538B1 (en) 2022-07-05
US20150079166A1 (en) 2015-03-19
EP2826477A1 (en) 2015-01-21
CN104334169B (en) 2016-11-02
WO2014163132A1 (en) 2014-10-09
EP2826477A4 (en) 2015-09-09
BR112014029538A2 (en) 2017-06-27

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