IN2014MN02080A - - Google Patents

Info

Publication number
IN2014MN02080A
IN2014MN02080A IN2080MUN2014A IN2014MN02080A IN 2014MN02080 A IN2014MN02080 A IN 2014MN02080A IN 2080MUN2014 A IN2080MUN2014 A IN 2080MUN2014A IN 2014MN02080 A IN2014MN02080 A IN 2014MN02080A
Authority
IN
India
Prior art keywords
ala
amino acids
following amino
shaped
following
Prior art date
Application number
Inventor
Gennady Petrovich Vlasov
Arkadiy Mihajlovich Kotin
Original Assignee
Kotin Oleg Arkadyevich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotin Oleg Arkadyevich filed Critical Kotin Oleg Arkadyevich
Publication of IN2014MN02080A publication Critical patent/IN2014MN02080A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

?What are proposed are: synthetic peptides having a non narcotic type of analgesic effect of general formula 1 [SEQ ID NO:1] where: H is hydrogen XDL is an omission of an amino acid or is L Tyr XDL1 is one of the following amino acids: L Leu L Ala or D Ala XDL2 is one of the following amino acids: L His D His L Ala or D Ala XDL3 is one of the following amino acids: L Gln L Ala or D Ala; R2 is ??? or NH2 and also retro inversion peptides of formula (I) having a reverse sequence of amino acids with L shaped amino acids being substituted by D shaped amino acids and D shaped amino acids being substituted by L shaped amino acids of general formula 2 [SEQ ID NO:2] where: H is hydrogen XDL4 is one of the following amino acids: D GIn D Ala or L Ala XDL5 is one of the following amino acids: D His L His D Ala or L Ala XDL6 is one of the following amino acids: D Leu D Ala or L Ala XDL7 is an omission of an amino acid or is D Tyr R2 is ??? or NH2.
IN2080MUN2014 2012-03-22 2012-12-07 IN2014MN02080A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2012110908/10A RU2508295C2 (en) 2012-03-22 2012-03-22 Synthetic peptides with non-narcotic type of analgetic action
PCT/RU2012/001036 WO2013141750A1 (en) 2012-03-22 2012-12-07 Synthetic peptides wtih a non-narcotic type of analgesic effect

Publications (1)

Publication Number Publication Date
IN2014MN02080A true IN2014MN02080A (en) 2015-08-21

Family

ID=49223070

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2080MUN2014 IN2014MN02080A (en) 2012-03-22 2012-12-07

Country Status (8)

Country Link
US (1) US9260482B2 (en)
EP (1) EP2848629B1 (en)
JP (1) JP6118392B2 (en)
CA (1) CA2867994C (en)
ES (1) ES2651265T3 (en)
IN (1) IN2014MN02080A (en)
RU (1) RU2508295C2 (en)
WO (1) WO2013141750A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2678571C1 (en) * 2013-12-19 2019-01-30 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Therapeutic and/or preventive agent comprising 1-indansulfamide derivative for pain
DE102016125645A1 (en) 2016-12-23 2018-06-28 Forschungszentrum Jülich GmbH D-enantiomeric peptides for the treatment of chronic and neuropathic pain
RU2651491C1 (en) 2017-04-07 2018-04-19 Общество с ограниченной ответственностью "Биофармокс" Specific peptide clathrin inhibitors
US20210228677A1 (en) * 2020-01-28 2021-07-29 Pharmbiotech OY Pharmaceutical composition and a method for its manufacture

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229658B (en) 1989-04-21 1991-09-06 Eniricerche Spa BACK-REVERSE THYOPENTINE ANALOGUES WITH ONE OR MORE LINKS, THE METHOD FOR THEIR SYNTHESIS AND THEIR USE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS.
US5175146A (en) * 1989-12-05 1992-12-29 Vical, Inc. Synthetic calcitonin peptides

Also Published As

Publication number Publication date
JP6118392B2 (en) 2017-04-19
CA2867994C (en) 2017-05-16
RU2012110908A (en) 2013-09-27
JP2015512385A (en) 2015-04-27
EP2848629A4 (en) 2016-03-02
US20150073123A1 (en) 2015-03-12
CA2867994A1 (en) 2013-09-26
EP2848629B1 (en) 2017-09-06
ES2651265T3 (en) 2018-01-25
RU2508295C2 (en) 2014-02-27
US9260482B2 (en) 2016-02-16
WO2013141750A1 (en) 2013-09-26
EP2848629A1 (en) 2015-03-18

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