IN2014MN01750A - - Google Patents

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Publication number
IN2014MN01750A
IN2014MN01750A IN1750MUN2014A IN2014MN01750A IN 2014MN01750 A IN2014MN01750 A IN 2014MN01750A IN 1750MUN2014 A IN1750MUN2014 A IN 1750MUN2014A IN 2014MN01750 A IN2014MN01750 A IN 2014MN01750A
Authority
IN
India
Prior art keywords
synthesis
fondaparinux
relates
related compounds
anticoagulent
Prior art date
Application number
Inventor
Payal Parth Patel
Chun Ma
Kevin K Ohrr
Sourena Nadji
Original Assignee
Reliable Biopharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reliable Biopharmaceutical Corp filed Critical Reliable Biopharmaceutical Corp
Publication of IN2014MN01750A publication Critical patent/IN2014MN01750A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Abstract

The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates in addition to efficient and scalable processes for the synthesis of various intermediates useful in the synthesis of Fondaparinux and related compounds.
IN1750MUN2014 2012-02-02 2012-02-02 IN2014MN01750A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2012/023610 WO2013115817A1 (en) 2012-02-02 2012-02-02 An efficient and scalable process for the manufacture of fondaparinux sodium

Publications (1)

Publication Number Publication Date
IN2014MN01750A true IN2014MN01750A (en) 2015-07-03

Family

ID=45774313

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1750MUN2014 IN2014MN01750A (en) 2012-02-02 2012-02-02

Country Status (6)

Country Link
EP (1) EP2809678B1 (en)
CN (1) CN104144938B (en)
CA (2) CA3083488A1 (en)
ES (1) ES2635413T3 (en)
IN (1) IN2014MN01750A (en)
WO (1) WO2013115817A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103570774B (en) * 2012-08-07 2017-08-25 博瑞生物医药（苏州）股份有限公司 A kind of purification process of pentose compound
AU2013395144B2 (en) * 2013-07-25 2017-12-14 Scinopharm Taiwan, Ltd. Process for the production of Fondaparinux sodium
US10072039B2 (en) 2013-07-25 2018-09-11 Scinopharm Taiwan, Ltd. Process for the production of Fondaparinux sodium
AU2013395146A1 (en) * 2013-07-25 2016-02-18 Scinopharm Taiwan, Ltd. Process for the production of Fondaparinux sodium
CN104418924B (en) * 2013-08-28 2018-06-08 博瑞生物医药（苏州）股份有限公司 A kind of intermediate of pentose compound and preparation method thereof
CN103601766B (en) * 2013-09-30 2016-04-20 上海艾康睿医药科技有限公司 Fondaparinux sodium pentasaccharide intermediate and preparation method thereof
CN105622678A (en) * 2014-11-05 2016-06-01 海门慧聚药业有限公司 Novel technology for preparing disaccharide fragment of fondaparinux sodium intermediate
CN107686495B (en) * 2017-09-19 2018-08-31 江苏美迪克化学品有限公司 A kind of synthetic method of Fondaparinux sodium intermediate
CN107501353B (en) * 2017-09-19 2018-08-03 江苏美迪克化学品有限公司 A kind of preparation method of Fondaparinux sodium intermediate
CN109096348B (en) * 2018-09-12 2020-06-16 江苏美迪克化学品有限公司 Preparation method of fondaparinux sodium monosaccharide intermediate
WO2021142312A1 (en) * 2020-01-10 2021-07-15 The Board Of Regents Of The University Of Texas Methods and compositions related to heparinoids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818816A (en) 1981-04-28 1989-04-04 Choay, S.A. Process for the organic synthesis of oligosaccharides and derivatives thereof
JPS63218691A (en) * 1987-03-09 1988-09-12 Rikagaku Kenkyusho Novel pentasaccharide compound, production thereof, anticoagulant and antithrombotic agent
AU2008200567B2 (en) 2001-09-07 2008-04-24 Dr. Reddy's Laboratories Sa Synthetic Heparin Pentasaccharides
US7468358B2 (en) 2004-06-16 2008-12-23 Paringenix, Inc. Method and medicament for sulfated polysaccharide treatment of heparin-induced thrombocytopenia (HIT) syndrome
EP3666786A1 (en) * 2009-07-31 2020-06-17 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof

Also Published As

Publication number Publication date
EP2809678A1 (en) 2014-12-10
CA3083488A1 (en) 2013-08-08
CA2862606C (en) 2020-08-25
CN104144938A (en) 2014-11-12
CN104144938B (en) 2017-03-01
CA2862606A1 (en) 2013-08-08
EP2809678B1 (en) 2017-03-22
ES2635413T3 (en) 2017-10-03
WO2013115817A1 (en) 2013-08-08

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