IN2014MN01506A - - Google Patents

Info

Publication number
IN2014MN01506A
IN2014MN01506A IN1506MUN2014A IN2014MN01506A IN 2014MN01506 A IN2014MN01506 A IN 2014MN01506A IN 1506MUN2014 A IN1506MUN2014 A IN 1506MUN2014A IN 2014MN01506 A IN2014MN01506 A IN 2014MN01506A
Authority
IN
India
Prior art keywords
sample
molecular
gaseous
species
aerosol
Prior art date
Application number
Inventor
Daniel Szalay
Lajos Godorhazy
Zoltan Takats
Original Assignee
Medimass Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimass Kft filed Critical Medimass Kft
Publication of IN2014MN01506A publication Critical patent/IN2014MN01506A/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H01J49/142—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers using a solid target which is not previously vapourised
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0454—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for vaporising using mechanical energy, e.g. by ultrasonic vibrations
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Dispersion Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

According to some embodiments systems and methods for surface impact ionization of liquid phase and aerosol samples are provided. The method includes accelerating a liquid or aerosol sample colliding the sample with a solid collision surface thereby disintegrating the sample into both molecular ionic species (e.g. gaseous molecular ions) and molecular neutral species (e.g. gaseous sample) and transporting the disintegrated sample to an ion analyzer. Some embodiments of the method further comprise discarding the molecular neutral species. Such embodiments transport substantially only the molecular ionic species to the ion analyzer.
IN1506MUN2014 2011-12-28 2012-12-28 IN2014MN01506A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161580715P 2011-12-28 2011-12-28
PCT/IB2012/002995 WO2013098642A2 (en) 2011-12-28 2012-12-28 Collision ion generator and separator

Publications (1)

Publication Number Publication Date
IN2014MN01506A true IN2014MN01506A (en) 2015-05-01

Family

ID=47780098

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1506MUN2014 IN2014MN01506A (en) 2011-12-28 2012-12-28

Country Status (7)

Country Link
US (2) US9287100B2 (en)
EP (2) EP3699950B1 (en)
JP (1) JP6320933B2 (en)
CN (2) CN108511315B (en)
IL (1) IL233401A0 (en)
IN (1) IN2014MN01506A (en)
WO (1) WO2013098642A2 (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3699950B1 (en) * 2011-12-28 2026-01-28 Micromass UK Limited Collision ion generator and separator
US9953819B2 (en) 2014-02-26 2018-04-24 Micromass Uk Limited Impactor spray atmospheric pressure ion source with target paddle
GB201403370D0 (en) * 2014-02-26 2014-04-09 Micromass Ltd Impactor spray atmospheric pressure ion source with target paddle
JP6800875B2 (en) 2015-03-06 2020-12-16 マイクロマス ユーケー リミテッド Inflow instrument for ion analyzers connected to rapid evaporation ionized mass spectrometry (“REIMS”) equipment
EP3264989B1 (en) 2015-03-06 2023-12-20 Micromass UK Limited Spectrometric analysis
CN107636794B (en) 2015-03-06 2020-02-28 英国质谱公司 Liquid trap or separator for electrosurgical applications
GB2601669B (en) * 2015-03-06 2022-08-31 Micromass Ltd Collision surface for improved ionisation
EP4174906A1 (en) 2015-03-06 2023-05-03 Micromass UK Limited Improved ionisation of gaseous samples
CN112964625B (en) * 2015-03-06 2024-06-07 英国质谱公司 Cell population analysis
WO2016142696A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
KR102092047B1 (en) * 2015-03-06 2020-03-24 마이크로매스 유케이 리미티드 In vivo endoscopic tissue identification tool
EP3570315B1 (en) 2015-03-06 2024-01-31 Micromass UK Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of biopsy samples
CN107667288B (en) * 2015-03-06 2022-02-01 英国质谱公司 Spectral analysis of microorganisms
WO2016142675A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Imaging guided ambient ionisation mass spectrometry
US11037774B2 (en) 2015-03-06 2021-06-15 Micromass Uk Limited Physically guided rapid evaporative ionisation mass spectrometry (“REIMS”)
US11342170B2 (en) 2015-03-06 2022-05-24 Micromass Uk Limited Collision surface for improved ionisation
GB2553941B (en) * 2015-03-06 2021-02-17 Micromass Ltd Chemically guided ambient ionisation mass spectrometry
CN107635478A (en) * 2015-03-06 2018-01-26 英国质谱公司 The fabric analysis carried out by mass spectrum or ion mobility spectrometry
WO2017049403A1 (en) 2015-09-22 2017-03-30 University Health Network System and method for optimized mass spectrometry analysis
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
GB201522594D0 (en) * 2015-12-22 2016-02-03 Micromass Ltd Secondary ultrasonic nebulisation
GB201601319D0 (en) * 2016-01-25 2016-03-09 Micromass Ltd Methods for analysing electronic cigarette smoke
WO2017178833A1 (en) 2016-04-14 2017-10-19 Micromass Uk Limited Spectrometric analysis of plants
GB2563194B (en) * 2016-04-21 2020-08-05 Waters Technologies Corp Dual mode ionization device
GB201609952D0 (en) * 2016-06-07 2016-07-20 Micromass Ltd Combined optical and mass spectral tissue ID probes
EP3469623A4 (en) * 2016-06-10 2020-01-22 University Health Network SOFT IONIZATION SYSTEM AND METHOD OF USING THE SAME
GB2567793B (en) * 2017-04-13 2023-03-22 Micromass Ltd A method of fragmenting and charge reducing biomolecules
GB2566326A (en) * 2017-09-11 2019-03-13 Owlstone Inc Ion mobility filter
GB201808894D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
CN112154531B (en) 2018-05-31 2024-05-17 英国质谱公司 Mass spectrometer
GB201808892D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
GB201808932D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808890D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808936D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808949D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808893D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
WO2019229463A1 (en) 2018-05-31 2019-12-05 Micromass Uk Limited Mass spectrometer having fragmentation region
GB201808912D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201811383D0 (en) * 2018-07-11 2018-08-29 Micromass Ltd Impact ionisation ion source
CN110553951B (en) * 2019-08-27 2021-06-08 清华大学 A particle impact and observation device and method
GB201915843D0 (en) * 2019-10-31 2019-12-18 Micromass Ltd Ion source
CN110808205B (en) * 2019-11-13 2022-03-18 宁波谱秀医疗设备有限责任公司 Ion source
GB2624012A (en) * 2022-11-04 2024-05-08 Thermo Fisher Scient Bremen Gmbh Enhancing mass spectrometer signals

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479545A (en) 1967-05-16 1969-11-18 Hughes Aircraft Co Surface ionization apparatus and electrode means for accelerating the ions in a curved path
HU191642B (en) 1984-03-21 1987-03-30 Adam Kovacs Method and instrument for discriminating from one another and separating by way of operation organic tissues
US4935624A (en) 1987-09-30 1990-06-19 Cornell Research Foundation, Inc. Thermal-assisted electrospray interface (TAESI) for LC/MS
US5559326A (en) 1995-07-28 1996-09-24 Hewlett-Packard Company Self generating ion device for mass spectrometry of liquids
EP0819937A3 (en) 1996-07-19 2000-03-29 The University Of Nottingham Apparatus and methods for the analysis of trace constituents in gases
US5756995A (en) 1997-07-09 1998-05-26 The United States Of America As Represented By The Secretary Of The Army Ion interface for mass spectrometer
US20020001544A1 (en) 1997-08-28 2002-01-03 Robert Hess System and method for high throughput processing of droplets
US5920068A (en) 1998-03-05 1999-07-06 Micron Technology, Inc. Analysis of semiconductor surfaces by secondary ion mass spectrometry
US7329253B2 (en) 2003-12-09 2008-02-12 Rubicor Medical, Inc. Suction sleeve and interventional devices having such a suction sleeve
WO2000036398A2 (en) 1998-12-14 2000-06-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Method and devices for detecting optical properties, especially luminescence reactions and refraction behaviour of molecules which are directly or indirectly bound on a support
US7119342B2 (en) 1999-02-09 2006-10-10 Syagen Technology Interfaces for a photoionization mass spectrometer
US6280302B1 (en) 1999-03-24 2001-08-28 Flow International Corporation Method and apparatus for fluid jet formation
US6375635B1 (en) 1999-05-18 2002-04-23 Hydrocision, Inc. Fluid jet surgical instruments
DE19934173A1 (en) * 1999-07-21 2001-01-25 Max Planck Gesellschaft Fragmenting clusters with a carrier substance, using a reagent charge which forms part of the cluster fragments to produce and manipulate electrically neutral particles effectively
US6531318B1 (en) 1999-10-08 2003-03-11 The General Hospital Corporation Methods and apparatus for cell analysis
US6777672B1 (en) 2000-02-18 2004-08-17 Bruker Daltonics, Inc. Method and apparatus for a multiple part capillary device for use in mass spectrometry
AU2001263712A1 (en) 2000-06-20 2002-01-02 Ammann-Technik Ag Device for producing a liquid jet for removing especially biological tissue, anduse thereof
WO2002014849A1 (en) 2000-08-16 2002-02-21 Vanderbilt University System and method of infrared matrix-assisted laser desorption/ionization mass spectrometry in polyacrylamide gels
US6744043B2 (en) 2000-12-08 2004-06-01 Mds Inc. Ion mobilty spectrometer incorporating an ion guide in combination with an MS device
US20030119193A1 (en) 2001-04-25 2003-06-26 Robert Hess System and method for high throughput screening of droplets
US6812030B2 (en) * 2001-04-25 2004-11-02 Biotrove, Inc. System and method for high throughput sample preparation and analysis using column chromatography
JP3725803B2 (en) 2001-06-15 2005-12-14 株式会社東芝 Semiconductor wafer impurity measurement method and semiconductor wafer impurity measurement program
EP1291659A3 (en) 2001-09-06 2008-05-21 Sysmex Corporation Automatic sample analyzer and its components
WO2003031931A2 (en) 2001-10-05 2003-04-17 Yale University Method and apparatus to produce ions and nanodrops from taylor cones of volatile liquids at reduced pressures
US6756586B2 (en) 2001-10-15 2004-06-29 Vanderbilt University Methods and apparatus for analyzing biological samples by mass spectrometry
EP1448769A4 (en) 2001-10-31 2006-02-01 Ionfinity Llc Soft ionization device and applications thereof
US7005633B2 (en) 2002-02-08 2006-02-28 Ionalytics Corporation Method and apparatus for desolvating ions for introduction into a FAIMS analyzer region
KR101011168B1 (en) 2002-04-26 2011-01-26 토탈 페트로케미칼스 리서치 펠루이 Rotomolded articles made of polyethylene
AU2003295316A1 (en) 2002-05-31 2004-04-19 University Of Florida Research Foundation, Inc. Methods and devices for laser desorption chemical ionization
WO2004034011A2 (en) 2002-10-10 2004-04-22 Universita' Degli Studi Di Milano Ionization source for mass spectrometry analysis
EP1555954B1 (en) 2002-10-17 2010-04-14 Braun GmbH Mouth rinse and spray nozzle for creating a liquid jet and teeth-cleaning system
JP2004212073A (en) 2002-12-27 2004-07-29 Hitachi Ltd Dangerous goods detection device and dangerous goods detection method
JP2004264043A (en) 2003-01-31 2004-09-24 National Institute Of Advanced Industrial & Technology Ionizer and micro area analyzer
KR100466866B1 (en) 2003-04-24 2005-01-24 전명기 Electrode for radiofrequency tissue ablation
CA2470452C (en) 2003-06-09 2017-10-03 Ionics Mass Spectrometry Group, Inc. Mass spectrometer interface
US7025196B2 (en) 2003-07-21 2006-04-11 Fmc Technologies, Inc. Friction drive conveyor
US20050017091A1 (en) 2003-07-22 2005-01-27 Omax Corporation Abrasive water-jet cutting nozzle having a vented water-jet pathway
US20050077644A1 (en) 2003-08-14 2005-04-14 Bryan David E. High pressure liquid jet cutting system and method for forming polymer pellets
US7217919B2 (en) 2004-11-02 2007-05-15 Analytica Of Branford, Inc. Method and apparatus for multiplexing plural ion beams to a mass spectrometer
US7260914B2 (en) 2003-12-27 2007-08-28 Floral Transport Systems, Llc Method and apparatus for packaging horticultural products
AU2005200016B2 (en) 2004-01-09 2010-12-09 John Bean Technologies Corporation Method and system for portioning workpieces to user-scanned shape and other specifications
US20070023631A1 (en) 2004-03-30 2007-02-01 Zoltan Takats Parallel sample handling for high-throughput mass spectrometric analysis
US7335897B2 (en) 2004-03-30 2008-02-26 Purdue Research Foundation Method and system for desorption electrospray ionization
US7199364B2 (en) 2004-05-21 2007-04-03 Thermo Finnigan Llc Electrospray ion source apparatus
WO2006013573A2 (en) 2004-08-06 2006-02-09 Mendy Erad Ltd. Early detection of harmful agents: method, system and kit
US7094135B2 (en) 2004-08-10 2006-08-22 International Waterjet Parts, Inc. Abrasivejet cutting head with back-flow prevention valve
DE102004053064B4 (en) * 2004-11-03 2007-11-08 Bruker Daltonik Gmbh Ionization by droplet impact
US6998622B1 (en) 2004-11-17 2006-02-14 Agilent Technologies, Inc. On-axis electron impact ion source
IL166115A (en) 2005-01-03 2012-06-28 Dan Adam Interactive ultrasound-based depth measurement for medical applications
WO2006081240A1 (en) 2005-01-27 2006-08-03 The George Washington University Protein microscope
US7196525B2 (en) 2005-05-06 2007-03-27 Sparkman O David Sample imaging
US7351960B2 (en) 2005-05-16 2008-04-01 Thermo Finnigan Llc Enhanced ion desolvation for an ion mobility spectrometry device
US20070023677A1 (en) 2005-06-29 2007-02-01 Perkins Patrick D Multimode ionization source and method for screening molecules
WO2007041452A2 (en) 2005-09-30 2007-04-12 New York University Methods for preparation of live body tissue for examination
US7828948B1 (en) 2005-10-06 2010-11-09 Sandia Corporation Preconcentration and separation of analytes in microchannels
US20070094389A1 (en) 2005-10-23 2007-04-26 Bill Nussey Provision of rss feeds based on classification of content
US7459676B2 (en) 2005-11-21 2008-12-02 Thermo Finnigan Llc MALDI/LDI source
JP2007170870A (en) 2005-12-19 2007-07-05 Protosera Inc Insitu detection method using mass analysis
US7687772B2 (en) 2006-01-27 2010-03-30 National Sun Yat-Sen University Mass spectrometric imaging method under ambient conditions using electrospray-assisted laser desorption ionization mass spectrometry
TWI271771B (en) 2006-01-27 2007-01-21 Univ Nat Sun Yat Sen Electrospray-assisted laser desorption ionization devices, mass spectrometers, and methods for mass spectrometry
US7462824B2 (en) 2006-04-28 2008-12-09 Yang Wang Combined ambient desorption and ionization source for mass spectrometry
EP1855306B1 (en) 2006-05-11 2019-11-13 ISB - Ion Source & Biotechnologies S.R.L. Ionization source and method for mass spectrometry
EP2035122A4 (en) 2006-05-26 2010-05-05 Ionsense Inc OPEN FLEXIBLE TUBE SAMPLING SYSTEM FOR USE WITH SURFACE IONIZATION TECHNOLOGY
HU226837B1 (en) 2006-05-31 2009-12-28 Semmelweis Egyetem Flow-ray desorption ionization method and device
JP5142580B2 (en) 2006-06-29 2013-02-13 キヤノン株式会社 Surface analysis method and surface analysis apparatus
CA2659830A1 (en) 2006-07-11 2008-01-17 Excellims Corporation Methods and apparatus for the ion mobility based separation and collection of molecules
US7928364B2 (en) 2006-10-13 2011-04-19 Ionsense, Inc. Sampling system for containment and transfer of ions into a spectroscopy system
JP2008147165A (en) 2006-10-30 2008-06-26 National Sun Yat-Sen Univ Laser desorption equipment, mass spectrometer assembly and environmental liquid mass spectrometry
US20090283674A1 (en) * 2006-11-07 2009-11-19 Reinhold Pesch Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method
CN101606219B (en) * 2006-11-07 2012-06-20 塞莫费雪科学（不来梅）有限公司 ion transport device
US7718958B2 (en) 2006-11-17 2010-05-18 National Sun Yat-Sen University Mass spectroscopic reaction-monitoring method
US20090065714A1 (en) 2006-11-30 2009-03-12 Keady John P Eletrofluid collisional accelerator and fusion reactor
US8193487B2 (en) 2007-03-16 2012-06-05 Inficon, Inc. Portable light emitting sampling probe
US7564028B2 (en) 2007-05-01 2009-07-21 Virgin Instruments Corporation Vacuum housing system for MALDI-TOF mass spectrometry
US20080312651A1 (en) 2007-06-15 2008-12-18 Karl Pope Apparatus and methods for selective heating of tissue
US8901487B2 (en) 2007-07-20 2014-12-02 George Washington University Subcellular analysis by laser ablation electrospray ionization mass spectrometry
US20100186524A1 (en) 2008-02-05 2010-07-29 Enertechnix, Inc Aerosol Collection and Microdroplet Delivery for Analysis
US20100096546A1 (en) 2008-06-23 2010-04-22 Northrop Grumman Systems Corporation Solution Analysis Using Atmospheric Pressure Ionization Techniques
US8253098B2 (en) 2008-06-27 2012-08-28 University Of Yamanashi Ionization analysis method and apparatus
US20100280409A1 (en) 2008-09-30 2010-11-04 Mark Joseph L Real-time pathology
US8203117B2 (en) 2008-09-30 2012-06-19 Prosolia, Inc. Method and apparatus for embedded heater for desorption and ionization of analytes
EP2338160A4 (en) 2008-10-13 2015-12-23 Purdue Research Foundation SYSTEMS AND METHODS FOR ION TRANSFER FOR ANALYSIS
EP2415067B1 (en) 2009-04-01 2017-12-20 Prosolia, Inc. Method and system for surface sampling
KR101787016B1 (en) * 2009-05-27 2017-10-18 마이크로매스 유케이 리미티드 System and method for identification of biological tissues
DE102009050040B4 (en) 2009-08-28 2014-10-30 Bruker Daltonik Gmbh Inlet of ions in mass spectrometer through Laval nozzles
US8299444B2 (en) 2009-09-02 2012-10-30 Shimadzu Research Laboratory (Shanghai) Co. Ltd. Ion source
GB2466350B (en) 2009-11-30 2011-06-08 Microsaic Systems Ltd Mass spectrometer system
US8591459B2 (en) 2009-12-21 2013-11-26 Ethicon Endo-Surgery, Inc. Use of biomarkers and therapeutic agents with surgical devices
JP5521177B2 (en) 2010-04-28 2014-06-11 株式会社島津製作所 Mass spectrometer
US8834462B2 (en) 2010-06-01 2014-09-16 Covidien Lp System and method for sensing tissue characteristics
CN103370615A (en) 2010-10-25 2013-10-23 华盛顿大学商业中心 Method and system for simultaneously finding and measuring multiple analytes from complex samples
GB201109414D0 (en) 2011-06-03 2011-07-20 Micromass Ltd Diathermy -ionisation technique
US8723111B2 (en) 2011-09-29 2014-05-13 Morpho Detection, Llc Apparatus for chemical sampling and method of assembling the same
EP3699950B1 (en) * 2011-12-28 2026-01-28 Micromass UK Limited Collision ion generator and separator

Also Published As

Publication number Publication date
CN108511315B (en) 2021-01-08
US10242858B2 (en) 2019-03-26
CN108511315A (en) 2018-09-07
EP2798657B1 (en) 2020-05-06
CN104254901A (en) 2014-12-31
US9287100B2 (en) 2016-03-15
CN104254901B (en) 2018-05-04
JP2015504160A (en) 2015-02-05
US20160247668A1 (en) 2016-08-25
EP2798657A2 (en) 2014-11-05
EP3699950B1 (en) 2026-01-28
WO2013098642A3 (en) 2014-01-03
IL233401A0 (en) 2014-08-31
EP3699950A1 (en) 2020-08-26
US20140353489A1 (en) 2014-12-04
WO2013098642A2 (en) 2013-07-04
JP6320933B2 (en) 2018-05-09

Similar Documents

Publication Publication Date Title
IN2014MN01506A (en)
WO2013005061A3 (en) Photo-dissociation of proteins and peptides in a mass spectrometer
GB201308854D0 (en) Excitation of reagent molecules within a RF confined ion guide or ion trap to perform ion molecule, ion radical or ion-ion interaction experiments
IN2012DN02538A (en)
WO2013098645A3 (en) System and method for rapid evaporative ionization of liquid phase samples
WO2011106750A3 (en) Method and apparatus for enhanced lifetime and performance of ion source in an ion implantation system
GB2546060A8 (en) Multi detector mass spectrometer and spectrometry method
WO2014118122A3 (en) Method for mass spectrometric examination of gas mixtures and mass spectrometer therefor
WO2012100120A3 (en) Synchronization of ion generation with cycling of a discontinuous atmospheric interface
WO2008067395A3 (en) Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection
WO2012024468A3 (en) Time-of-flight mass spectrometer with accumulating electron impact ion source
WO2013104583A3 (en) Apparatus and method for surface processing of a substrate
GB201220008D0 (en) Data acquisition modes for ION mobility time-of-flight mass spectrometry
EP3062331A3 (en) Ambient desorption, ionization, and excitation for spectrometry
WO2012157867A3 (en) Flight time based mass miscroscope system for ultra high-speed multi mode mass analysis
WO2013171501A3 (en) Orthogonal acceleration coaxial cylinder time of flight mass analyser
MX2021014807A (en) In situ chemical transformation and ionization of inorganic perchlorates on surfaces.
GB201119059D0 (en) Improvements to tof mass spectrometers using linear accelerator devices
GB201122208D0 (en) Improved space focus time of flight mass spectrometer
WO2012028940A3 (en) Ion source for mass spectrometry
EP3268505A4 (en) Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
WO2011035260A3 (en) Distributed ion source acceleration column
GB201307089D0 (en) Ion Generation in Mass Spectrometers by Cluster Bombardment
JP2020507883A5 (en)
WO2008090600A1 (en) Mass analyzer