IN2014MN01484A - - Google Patents
Info
- Publication number
- IN2014MN01484A IN2014MN01484A IN1484MUN2014A IN2014MN01484A IN 2014MN01484 A IN2014MN01484 A IN 2014MN01484A IN 1484MUN2014 A IN1484MUN2014 A IN 1484MUN2014A IN 2014MN01484 A IN2014MN01484 A IN 2014MN01484A
- Authority
- IN
- India
- Prior art keywords
- composition
- ingredients
- insulin
- acylated
- level
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to pharmaceutics and medicine and more specifically to compositions of a biologically active substance in particular supramolecular assemblies of acylated insulin oligopeptides for oral administration in the treatment of diabetes mellitus and complications thereof. The proposed system makes it possible using a single oral dose to maintain the level of glucose in the blood at a physiological level for 24 hours (super effect) and the ingredients of the system acquire resistance to enzymatic action have small dimensions and can be easily absorbed from the intestines. Essence of the invention: The principle active agents are in the form of a supramolecular composition namely an assembly consisting of acylated oligopeptide products of the enzymatic hydrolysis of insulin. The composition can be produced industrially in sufficient amounts on account of the availability of all of the ingredients of the composition.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU2011/001061 WO2013100793A1 (en) | 2011-12-28 | 2011-12-28 | Insulsin derivative with antihyperglycemic activity and method for the production thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN01484A true IN2014MN01484A (en) | 2015-05-01 |
Family
ID=48698085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1484MUN2014 IN2014MN01484A (en) | 2011-12-28 | 2011-12-28 |
Country Status (3)
| Country | Link |
|---|---|
| EA (1) | EA023447B1 (en) |
| IN (1) | IN2014MN01484A (en) |
| WO (1) | WO2013100793A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11191767B2 (en) | 2017-11-15 | 2021-12-07 | Boris Slavinovich FARBER | Pharmaceutical composition for stimulating stem cell division and suppressing bacterial virulence |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1226104B1 (en) * | 1999-11-05 | 2009-04-08 | Emisphere Technologies, Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| US20110293714A1 (en) * | 2008-11-28 | 2011-12-01 | Novo Nordisk A/S | Pharmaceutical compositions suitable for oral administration of derivatized insulin peptides |
-
2011
- 2011-12-28 IN IN1484MUN2014 patent/IN2014MN01484A/en unknown
- 2011-12-28 WO PCT/RU2011/001061 patent/WO2013100793A1/en active Application Filing
- 2011-12-28 EA EA201300207A patent/EA023447B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013100793A1 (en) | 2013-07-04 |
| EA023447B1 (en) | 2016-06-30 |
| EA201300207A1 (en) | 2014-01-30 |
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