IN2014MN01046A - - Google Patents

Info

Publication number
IN2014MN01046A
IN2014MN01046A IN1046MUN2014A IN2014MN01046A IN 2014MN01046 A IN2014MN01046 A IN 2014MN01046A IN 1046MUN2014 A IN1046MUN2014 A IN 1046MUN2014A IN 2014MN01046 A IN2014MN01046 A IN 2014MN01046A
Authority
IN
India
Prior art keywords
optically active
optical resolution
efficiently produced
performing optical
bicyclic compound
Prior art date
Application number
Inventor
Yoshitaka Nakamura
Takafumi Kitawaki
Takeshi Kaneda
Original Assignee
Daiichi Sankyo Companyltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Companyltd filed Critical Daiichi Sankyo Companyltd
Publication of IN2014MN01046A publication Critical patent/IN2014MN01046A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/80—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/12—Formation of amino and carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/85—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to a chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/20—All rings being cycloaliphatic the ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

An optically active bicyclic compound is efficiently produced by performing optical resolution using an optically active amine.
IN1046MUN2014 2011-12-15 2012-12-13 IN2014MN01046A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011274965 2011-12-15
PCT/JP2012/082355 WO2013089188A1 (en) 2011-12-15 2012-12-13 Optical resolution method for bicyclic compound using asymmetric catalyst

Publications (1)

Publication Number Publication Date
IN2014MN01046A true IN2014MN01046A (en) 2015-05-01

Family

ID=48612629

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1046MUN2014 IN2014MN01046A (en) 2011-12-15 2012-12-13

Country Status (13)

Country Link
US (1) US9035103B2 (en)
EP (1) EP2792664B1 (en)
JP (1) JP6017451B2 (en)
KR (1) KR101944575B1 (en)
CN (1) CN103987687B (en)
BR (1) BR112014014432B1 (en)
CA (1) CA2859003C (en)
ES (1) ES2686929T3 (en)
HU (1) HUE040225T2 (en)
IL (1) IL233104A (en)
IN (1) IN2014MN01046A (en)
TW (1) TWI546281B (en)
WO (1) WO2013089188A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI635071B (en) * 2013-07-08 2018-09-11 第一三共股份有限公司 OPTICALLY ACTIVE BICYCLIC γ-AMINO ACID AND PREPARATION METHOD FOR THE SAME
CN107667097B (en) * 2015-05-27 2021-02-12 诺瓦色生物公司 Separation of enantiomers of 3-ethylbicyclo [3.2.0] hept-3-en-6-one
WO2024134671A1 (en) * 2022-12-21 2024-06-27 Bhisaj Pharmaceuticals Pvt Ltd Preparation of 3-ethylbicyclo[3.2.0]hept-3-en-6-one
CN116903468B (en) * 2023-07-14 2024-01-26 山东新时代药业有限公司 A kind of preparation method of milopaline intermediate
CN117924061B (en) * 2024-01-17 2026-03-20 北京海步医药科技有限公司 A method for resolving 3-alkylbicyclo[3.2.0]hept-3-en-6-one
CN119798105A (en) * 2025-01-10 2025-04-11 长治医学院 Preparation method of milabalin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0074856A3 (en) * 1981-09-16 1984-02-01 Glaxo Group Limited Resolution of racemic bicycloheptenones
JPS60169434A (en) * 1984-02-14 1985-09-02 Ube Ind Ltd Preparation of optically active bicycloketone
KR100589066B1 (en) 1997-10-27 2006-06-13 워너-램버트 캄파니 엘엘씨 Cyclic Amino Acids Useful as Pharmaceuticals and Derivatives thereof
HN2000000224A (en) 1999-10-20 2001-04-11 Warner Lambert Co BICYCLE AMINO ACIDS AS PHARMACEUTICAL AGENTS
WO2002085839A1 (en) 2001-04-19 2002-10-31 Warner-Lambert Company Llc Fused bicyclic or tricyclic amino acids
AU2003248907B2 (en) 2002-07-11 2007-04-26 Merck & Co., Inc. Treatment of neuropathic pain with 6H-pyrrolo[3,4-d]pyridazine compounds
KR101409079B1 (en) * 2007-09-28 2014-06-18 다이이찌 산쿄 가부시키가이샤 BICYCLIC γ-AMINO ACID DERIVATIVE
JP5336751B2 (en) 2007-12-12 2013-11-06 日東電工株式会社 Liquid crystalline coating liquid and polarizing film
KR101674700B1 (en) 2009-03-26 2016-11-09 다이이찌 산쿄 가부시키가이샤 Method for producing 2-cyclic? -Amino acid derivatives
EP2719676B1 (en) * 2011-06-08 2017-12-13 Daiichi Sankyo Company, Limited Method for producing bicyclic compound via iminium salt

Also Published As

Publication number Publication date
EP2792664A4 (en) 2015-08-05
JPWO2013089188A1 (en) 2015-04-27
TW201332955A (en) 2013-08-16
TWI546281B (en) 2016-08-21
ES2686929T3 (en) 2018-10-22
KR101944575B1 (en) 2019-04-17
HK1199017A1 (en) 2015-06-19
CA2859003C (en) 2016-11-01
BR112014014432B1 (en) 2022-03-29
US20140296569A1 (en) 2014-10-02
CN103987687A (en) 2014-08-13
US9035103B2 (en) 2015-05-19
WO2013089188A1 (en) 2013-06-20
BR112014014432A2 (en) 2017-06-13
KR20140107250A (en) 2014-09-04
CN103987687B (en) 2015-12-02
IL233104A (en) 2016-08-31
EP2792664A1 (en) 2014-10-22
EP2792664B1 (en) 2018-07-04
JP6017451B2 (en) 2016-11-02
HUE040225T2 (en) 2019-02-28
IL233104A0 (en) 2014-08-03
CA2859003A1 (en) 2013-06-20

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