IN2014DN11257A - - Google Patents
Download PDFInfo
- Publication number
- IN2014DN11257A IN2014DN11257A IN11257DEN2014A IN2014DN11257A IN 2014DN11257 A IN2014DN11257 A IN 2014DN11257A IN 11257DEN2014 A IN11257DEN2014 A IN 11257DEN2014A IN 2014DN11257 A IN2014DN11257 A IN 2014DN11257A
- Authority
- IN
- India
- Prior art keywords
- inhalation formulation
- active ingredients
- dry powder
- pharmaceutically active
- copd
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Provided is a dry powder for inhalation formulation comprising salmeterol xinafoate fluticasone propionate and tiotropium bromide as pharmaceutically active ingredients and a carrier and an inhalation formulation comprising same. The inventive dry powder inhalation formulation having good content uniformity and showing small changes in the aerodynamic size distribution in accordance with the flow rate changes can effectively deliver said pharmaceutically active ingredients to a target site upon administration and thus can be useful in the prevention or treatment of respiratory diseases particularly asthma and COPD.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020120063665A KR20130140358A (en) | 2012-06-14 | 2012-06-14 | Dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate and tiotropium bromide, and method for preparing the same |
PCT/KR2013/004880 WO2013187626A1 (en) | 2012-06-14 | 2013-06-03 | Dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate and tiotropium bromide, and method for preparing same |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN11257A true IN2014DN11257A (en) | 2015-10-09 |
Family
ID=49758405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN11257DEN2014 IN2014DN11257A (en) | 2012-06-14 | 2013-06-03 |
Country Status (19)
Country | Link |
---|---|
US (2) | US9283232B2 (en) |
EP (1) | EP2861219A4 (en) |
JP (1) | JP2015519394A (en) |
KR (1) | KR20130140358A (en) |
CN (1) | CN104363895A (en) |
AU (1) | AU2013275113A1 (en) |
BR (1) | BR112014030910A2 (en) |
CA (1) | CA2876283A1 (en) |
HK (1) | HK1206602A1 (en) |
IL (1) | IL236198A0 (en) |
IN (1) | IN2014DN11257A (en) |
MX (1) | MX2014014755A (en) |
NZ (1) | NZ703788A (en) |
PH (1) | PH12014502746B1 (en) |
RU (1) | RU2015100905A (en) |
SG (1) | SG11201408292YA (en) |
TW (1) | TWI565481B (en) |
WO (1) | WO2013187626A1 (en) |
ZA (1) | ZA201500208B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2952510T3 (en) | 2014-06-30 | 2023-10-31 | Proveris Scient Corporation | Sampling apparatus for determining the quantity and uniformity of an administered dose of medication and related methods |
WO2016052897A1 (en) * | 2014-09-30 | 2016-04-07 | Hanmi Pharm. Co., Ltd. | Dry powder for inhalation formulation having improved stability of combined active ingredients |
MA41378A (en) * | 2015-01-20 | 2017-11-28 | Teva Branded Pharmaceutical Prod R & D Inc | DRY POWDER INHALER CONSISTING OF FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE |
KR20160117069A (en) * | 2015-03-31 | 2016-10-10 | 한미약품 주식회사 | Capsule for inhalation with improved stability of combined active ingredients |
BR112017023351B1 (en) * | 2015-05-01 | 2023-11-28 | Board Of Regents, The University Of Texas System | PHARMACEUTICAL COMPOSITION AND USE OF THE PHARMACEUTICAL COMPOSITION |
CA3016890A1 (en) | 2016-03-09 | 2017-09-14 | Proveris Scientific Corporation | Methods for measuring dose content uniformity performance of inhaler and nasal devices |
CN108066329B (en) * | 2016-11-11 | 2021-11-16 | 江苏恒瑞医药股份有限公司 | Preparation method of microparticles of fluticasone or derivatives thereof for inhalation |
KR102330428B1 (en) * | 2019-10-14 | 2021-11-24 | 한미약품 주식회사 | Dry powder for inhalation formulation and preparation method thereof |
CN116033893A (en) * | 2020-06-26 | 2023-04-28 | 迈兰制药英国有限公司 | Formulations comprising 5- [3- (3-hydroxyphenoxy) azetidin-1-yl ] -5-methyl-2, 2-diphenylhexanamide |
CN115266987B (en) * | 2022-07-31 | 2023-06-30 | 浙江知一药业有限责任公司 | Pharmaceutical composition for treating respiratory diseases |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9322014D0 (en) | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
GB0003935D0 (en) * | 2000-02-08 | 2000-04-12 | King S College London | Formulation for dry powder inhaler |
DE10130371A1 (en) | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | New drug compositions based on anticholinergics, corticosteroids and betamimetics |
GB0312148D0 (en) | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
SE527190C2 (en) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Administration of metered dry powder combined doses of finely divided dry medication powders involves selecting first and second medicaments for forming of pharmaceutical, combined doses |
GB0326632D0 (en) | 2003-11-14 | 2003-12-17 | Jagotec Ag | Dry powder formulations |
PE20081788A1 (en) * | 2007-02-19 | 2008-12-18 | Cipla Ltd | PHARMACEUTICAL COMBINATIONS |
BRPI0816255A2 (en) * | 2007-09-12 | 2015-03-17 | Glaxo Group Ltd | Pharmaceutical product, use of the product, method for the prophylaxis or treatment of diseases, and pharmaceutically acceptable composition. |
MX2011000405A (en) * | 2008-07-18 | 2011-03-04 | Prosonix Ltd | Process for improving crystallinity. |
AU2009276498A1 (en) * | 2008-07-30 | 2010-02-04 | Stc.Unm | Formulations containing large-size carrier particles for dry powder inhalation aerosols |
TR201000681A2 (en) * | 2010-01-29 | 2011-08-22 | B�Lg�� Mahmut | Dry powder formulations inhaled. |
-
2012
- 2012-06-14 KR KR1020120063665A patent/KR20130140358A/en not_active Application Discontinuation
-
2013
- 2013-06-03 CN CN201380030898.0A patent/CN104363895A/en active Pending
- 2013-06-03 IN IN11257DEN2014 patent/IN2014DN11257A/en unknown
- 2013-06-03 SG SG11201408292YA patent/SG11201408292YA/en unknown
- 2013-06-03 MX MX2014014755A patent/MX2014014755A/en unknown
- 2013-06-03 AU AU2013275113A patent/AU2013275113A1/en not_active Abandoned
- 2013-06-03 JP JP2015517171A patent/JP2015519394A/en active Pending
- 2013-06-03 WO PCT/KR2013/004880 patent/WO2013187626A1/en active Application Filing
- 2013-06-03 RU RU2015100905A patent/RU2015100905A/en not_active Application Discontinuation
- 2013-06-03 BR BR112014030910A patent/BR112014030910A2/en not_active IP Right Cessation
- 2013-06-03 NZ NZ703788A patent/NZ703788A/en not_active IP Right Cessation
- 2013-06-03 US US14/402,548 patent/US9283232B2/en not_active Expired - Fee Related
- 2013-06-03 CA CA2876283A patent/CA2876283A1/en not_active Abandoned
- 2013-06-03 EP EP13804439.1A patent/EP2861219A4/en not_active Withdrawn
- 2013-06-13 TW TW102120909A patent/TWI565481B/en not_active IP Right Cessation
-
2014
- 2014-12-09 PH PH12014502746A patent/PH12014502746B1/en unknown
- 2014-12-11 IL IL236198A patent/IL236198A0/en unknown
-
2015
- 2015-01-13 ZA ZA2015/00208A patent/ZA201500208B/en unknown
- 2015-06-22 US US14/746,225 patent/US9549936B2/en not_active Expired - Fee Related
- 2015-07-27 HK HK15107131.8A patent/HK1206602A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX2014014755A (en) | 2015-02-24 |
EP2861219A4 (en) | 2015-10-28 |
PH12014502746A1 (en) | 2015-02-02 |
US20150157566A1 (en) | 2015-06-11 |
PH12014502746B1 (en) | 2015-02-02 |
US9283232B2 (en) | 2016-03-15 |
CA2876283A1 (en) | 2013-12-19 |
SG11201408292YA (en) | 2015-01-29 |
KR20130140358A (en) | 2013-12-24 |
RU2015100905A (en) | 2016-08-10 |
BR112014030910A2 (en) | 2017-06-27 |
TWI565481B (en) | 2017-01-11 |
EP2861219A1 (en) | 2015-04-22 |
US9549936B2 (en) | 2017-01-24 |
IL236198A0 (en) | 2015-01-29 |
AU2013275113A1 (en) | 2015-02-05 |
NZ703788A (en) | 2016-10-28 |
JP2015519394A (en) | 2015-07-09 |
WO2013187626A1 (en) | 2013-12-19 |
TW201402154A (en) | 2014-01-16 |
US20150283151A1 (en) | 2015-10-08 |
ZA201500208B (en) | 2016-10-26 |
CN104363895A (en) | 2015-02-18 |
HK1206602A1 (en) | 2016-01-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2014DN11257A (en) | ||
TN2015000395A1 (en) | Respirable agglomerates of porous carrier particles and micronized drug | |
MX2010003935A (en) | Inhalation drug delivery. | |
TN2012000566A1 (en) | Dry powder formulation comprising an antimuscarinic drug | |
UA101653C2 (en) | Composition for inhalation comprising aclidinium for the treatment of asthma and chronic obstructive pulmonary disease | |
TR201000680A2 (en) | Pharmaceutical compositions containing tiotropium, formoterol and budesonide | |
MX2015015132A (en) | Inhalable pharmaceutical compositions and the inhaler devices containing them. | |
UA101652C2 (en) | Composition for inhalation comprising aclidinium for the treatment of asthma and chronic obstructive pulmonary disease | |
GEP201706767B (en) | Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation | |
PH12014502662A1 (en) | Novel dosage form and formulation of abediterol | |
MD20140131A2 (en) | Novel dosage and formulation for inhalation comprising aclidinium | |
EP4233874A3 (en) | Acetylsalicylic acid for reducing the risk of a thromboembolic event | |
WO2014007770A3 (en) | Inhalation compositions comprising corticosteroid and sorbitol | |
WO2014007781A3 (en) | Inhalation compositions | |
WO2011093815A3 (en) | Pharmaceutical compositions comprising formoterol and mometasone | |
WO2011093818A3 (en) | Pharmaceutical compositions comprising salmeterol and fluticasone | |
MY179794A (en) | Compound composition for inhalation used for treating asthma | |
MX2015009891A (en) | Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy. | |
WO2012030308A3 (en) | Formulation comprising cellobiose | |
MY187442A (en) | A pharmaceutical composition containing budesonide and formoterol | |
WO2011093811A3 (en) | Pharmaceutical preparations comprising formoterol and fluticasone | |
WO2011093812A3 (en) | Pharmaceutical formulation comprising tiotropium and budesonide in dry powder form | |
MY171271A (en) | Method for preparing metered dose sprayed inhaler for treating respiratory disease | |
WO2015027847A3 (en) | Administration method for preparation containing oseltamivir carboxylate guanidino analogues and/or ethyl esters thereof | |
WO2011093810A3 (en) | Dry powder pharmaceutical composition comprising tiotropium and mometasone |