IN2014DN09776A - - Google Patents

Info

Publication number
IN2014DN09776A
IN2014DN09776A IN9776DEN2014A IN2014DN09776A IN 2014DN09776 A IN2014DN09776 A IN 2014DN09776A IN 9776DEN2014 A IN9776DEN2014 A IN 9776DEN2014A IN 2014DN09776 A IN2014DN09776 A IN 2014DN09776A
Authority
IN
India
Prior art keywords
soluble
subject
level
methods
biological sample
Prior art date
Application number
Inventor
James V Snider
Timothy Edward Meyer
Craig Michael Stolen
Robert W Gerwien
Original Assignee
Critical Care Diagnostics Inc
Cardiac Pacemakers Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Critical Care Diagnostics Inc, Cardiac Pacemakers Inc filed Critical Critical Care Diagnostics Inc
Publication of IN2014DN09776A publication Critical patent/IN2014DN09776A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/3627Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39Heart defibrillators
    • A61N1/3956Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/715Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
    • G01N2333/7155Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/325Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/326Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Hospice & Palliative Care (AREA)
  • Surgery (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)

Abstract

Provided herein are methods that include (i) determining a level of soluble ST2 in a biological sample from a subject, (i) comparing the level of soluble ST2 in the biological sample to a reference level of soluble ST2 (e.g., a level of soluble ST2 in the subject at an earlier time point), and (iii) selecting, implanting , replacing, or reprogramming an implanted cardiac device, e.g., an ICD, CRT , or CRT- D device, for a subject having an elevated level of soluble ST2 in the biological sample compared to the reference level of soluble ST2, or selecting a subject for participation in , or stratifying a subject participating in , a clinical study of a treatment for reducing the risk of a ventricular tachyarrhythmia (VTA) event. Also provided are methods for evaluating the risk of a VTA event in a subject. Also provided are kits for performing any of these methods.
IN9776DEN2014 2012-05-18 2014-11-18 IN2014DN09776A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261649202P 2012-05-18 2012-05-18
PCT/US2013/041686 WO2013173778A1 (en) 2012-05-18 2013-05-17 Methods for treating or predicting risk of a ventricular tachyarrhythmia event

Publications (1)

Publication Number Publication Date
IN2014DN09776A true IN2014DN09776A (en) 2015-07-31

Family

ID=49584355

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9776DEN2014 IN2014DN09776A (en) 2012-05-18 2014-11-18

Country Status (11)

Country Link
US (3) US20130345805A1 (en)
EP (2) EP2849729B1 (en)
JP (2) JP6302896B2 (en)
CN (2) CN104507383B (en)
AU (2) AU2013262515B2 (en)
CA (1) CA2873896A1 (en)
ES (1) ES2709697T3 (en)
HK (1) HK1208624A1 (en)
IN (1) IN2014DN09776A (en)
MX (1) MX357740B (en)
WO (1) WO2013173778A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002218026A1 (en) 2000-11-09 2002-05-21 The Brigham And Women's Hospital, Inc. Cardiovascular disease diagnostic and therapeutic targets
DK2336359T3 (en) 2002-05-09 2016-05-30 Brigham & Womens Hospital 1L1RL-1 as cardiovascular disease marker
ATE476657T1 (en) 2006-04-24 2010-08-15 Critical Care Diagnostics Inc PREDICTION OF LETHALITY AND DETECTION OF SERIOUS DISEASES
ATE517341T1 (en) * 2006-04-27 2011-08-15 Critical Care Diagnostics Inc INTERLEUKIN-33 (IL-33) FOR THE DIAGNOSIS AND PREDICTION OF CARDIOVASCULAR DISEASES
EP2482078B1 (en) 2006-05-01 2016-02-03 Critical Care Diagnostics, Inc. Diagnosis of cardiovascular disease
ES2443125T3 (en) 2008-04-18 2014-02-17 Critical Care Diagnostics, Inc. Prediction of the risk of serious adverse cardiac events
CN103154027B (en) 2010-04-09 2016-06-29 重症监护诊断股份有限公司 Soluble human ST-2 antibody and analytic process
JP6215713B2 (en) 2011-03-17 2017-10-18 クリティカル ケア ダイアグノスティクス インコーポレイテッド How to predict the risk of adverse clinical outcomes
AU2012284039B2 (en) 2011-07-18 2017-03-30 Critical Care Diagnostics, Inc. Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy
EP2809392B1 (en) * 2012-01-31 2016-09-14 Cardiac Pacemakers, Inc. Implantable device and methods for diagnosing heart failure using biomarker panel data
WO2013116544A1 (en) 2012-01-31 2013-08-08 Cardiac Pacemakers, Inc. Systems and methods for controlling a cardiac resynchronisation device/therapy using biomarker panel data
MX357740B (en) * 2012-05-18 2018-07-23 Critical Care Diagnostics Inc Methods for treating or predicting risk of a ventricular tachyarrhythmia event.
RU2019107598A (en) 2012-08-16 2019-03-28 Критикал Кэа Дайэгностикс, Инк. METHODS FOR FORECASTING THE RISK OF DEVELOPMENT OF HYPERTENSION
RU2015110054A (en) 2012-08-21 2016-10-10 Критикал Кэа Дайэгностикс, Инк. MULTIMARKER STRATIFICATION OF RISK
CA3103560C (en) 2014-09-26 2023-01-17 Somalogic, Inc. Cardiovascular risk event prediction and uses thereof
US10079073B2 (en) 2014-12-11 2018-09-18 Critical Care Diagnostics, Inc. Test apparatus and methods for ST2 cardiac biomarker
US10324089B2 (en) 2014-12-11 2019-06-18 Critical Care Diagnostics, Inc. Test apparatus and methods for ST2 cardiac biomarker
US10188863B2 (en) * 2015-02-26 2019-01-29 Medtronic, Inc. Therapy program selection for electrical stimulation therapy based on a volume of tissue activation
JP7009977B2 (en) * 2017-12-25 2022-01-26 国立大学法人東海国立大学機構 Methods, devices and computer programs for predicting the severity and prognosis of heart disease using measurements of the subject's blood VEGF-A.
WO2020097190A1 (en) * 2018-11-06 2020-05-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Method of personalized treatment for cardiomyopathy and heart failure and associated diseases by measuring edema and cachexia/sarcopenia
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001218871A1 (en) 2000-03-21 2001-10-03 Takao Arai Monoclonal antibody and method and kit for the immunoassay of soluble human st2 with the use of the same
AU2002218026A1 (en) 2000-11-09 2002-05-21 The Brigham And Women's Hospital, Inc. Cardiovascular disease diagnostic and therapeutic targets
DK2336359T3 (en) 2002-05-09 2016-05-30 Brigham & Womens Hospital 1L1RL-1 as cardiovascular disease marker
US20060257558A1 (en) 2003-10-31 2006-11-16 Hiroshi Nomura Plasma polymerization of atomically modified surfaces
JP2007523324A (en) * 2004-02-05 2007-08-16 メドトロニック・インコーポレーテッド Method and apparatus for identifying a patient at risk for a life-threatening arrhythmia
ATE476657T1 (en) 2006-04-24 2010-08-15 Critical Care Diagnostics Inc PREDICTION OF LETHALITY AND DETECTION OF SERIOUS DISEASES
ATE517341T1 (en) 2006-04-27 2011-08-15 Critical Care Diagnostics Inc INTERLEUKIN-33 (IL-33) FOR THE DIAGNOSIS AND PREDICTION OF CARDIOVASCULAR DISEASES
EP2482078B1 (en) 2006-05-01 2016-02-03 Critical Care Diagnostics, Inc. Diagnosis of cardiovascular disease
US20100055683A1 (en) 2006-05-02 2010-03-04 Critical Care Diagnostics, Inc. Diagnosis of pulmonary and/or cardiovascular disease
EP2315034A3 (en) 2006-08-04 2011-08-17 Medizinische Hochschule Hannover Means and methods for assessing the risk of cardiac interventions based on GDF-15
EP1884777A1 (en) * 2006-08-04 2008-02-06 Medizinische Hochschule Hannover Means and methods for assessing the risk of cardiac interventions based on GDF-15
ATE533061T1 (en) * 2007-08-03 2011-11-15 Brahms Gmbh METHOD FOR DIAGNOSING BACTERIAL INFECTIONS
WO2009036011A2 (en) * 2007-09-11 2009-03-19 The Department Of Veterans Affairs Markers for ventricular arrhythmia
EP2107377A1 (en) * 2008-04-04 2009-10-07 BRAHMS Aktiengesellschaft Pro-endothelin-1 levels for the prediction of risk of tachyarrhytmic events
ES2443125T3 (en) 2008-04-18 2014-02-17 Critical Care Diagnostics, Inc. Prediction of the risk of serious adverse cardiac events
GB0818650D0 (en) 2008-10-10 2008-11-19 Uni I Oslo Methods
EP3178846B1 (en) * 2010-02-17 2018-08-22 Cedars-Sinai Medical Center Novel phosphorylation of cardiac troponin i as a monitor for cardiac injury
CN103154027B (en) 2010-04-09 2016-06-29 重症监护诊断股份有限公司 Soluble human ST-2 antibody and analytic process
JP6215713B2 (en) 2011-03-17 2017-10-18 クリティカル ケア ダイアグノスティクス インコーポレイテッド How to predict the risk of adverse clinical outcomes
AU2012284039B2 (en) 2011-07-18 2017-03-30 Critical Care Diagnostics, Inc. Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy
MX357740B (en) * 2012-05-18 2018-07-23 Critical Care Diagnostics Inc Methods for treating or predicting risk of a ventricular tachyarrhythmia event.
RU2019107598A (en) 2012-08-16 2019-03-28 Критикал Кэа Дайэгностикс, Инк. METHODS FOR FORECASTING THE RISK OF DEVELOPMENT OF HYPERTENSION
RU2015110054A (en) 2012-08-21 2016-10-10 Критикал Кэа Дайэгностикс, Инк. MULTIMARKER STRATIFICATION OF RISK

Also Published As

Publication number Publication date
AU2018204145A1 (en) 2018-06-28
CN104507383A (en) 2015-04-08
US20190391162A1 (en) 2019-12-26
CN109212223B (en) 2021-11-12
JP2018119976A (en) 2018-08-02
JP6600709B2 (en) 2019-10-30
WO2013173778A1 (en) 2013-11-21
AU2013262515A1 (en) 2014-12-04
US20130345805A1 (en) 2013-12-26
AU2013262515B2 (en) 2018-03-15
CN109212223A (en) 2019-01-15
EP2849729A1 (en) 2015-03-25
CA2873896A1 (en) 2013-11-21
EP2849729A4 (en) 2016-01-20
EP2849729B1 (en) 2018-11-14
EP3434260A1 (en) 2019-01-30
US20170146552A1 (en) 2017-05-25
JP6302896B2 (en) 2018-03-28
JP2015520371A (en) 2015-07-16
CN104507383B (en) 2018-08-28
US11340236B2 (en) 2022-05-24
ES2709697T3 (en) 2019-04-17
US10408845B2 (en) 2019-09-10
HK1208624A1 (en) 2016-03-11
MX2014013995A (en) 2015-09-04
MX357740B (en) 2018-07-23

Similar Documents

Publication Publication Date Title
IN2014DN09776A (en)
AU2017225061B2 (en) Biomarkers and methods of treating PD-1 and PD-L1 related conditions
MX362514B (en) Diagnostic assays and kits for detection of folate receptor 1.
WO2016196298A8 (en) Therapeutic and diagnostic methods for cancer
MX2014005800A (en) Human notch receptor mutations and their use.
EP3839510A3 (en) Blood-based biomarkers of tumor sensitivity to pd-1 antagonists
WO2012141844A3 (en) Methods predicting risk of an adverse clinical outcome
AU2017245629A1 (en) Diagnostic methods for patient specific therapeutic decision making in cancer care
ATE510583T1 (en) DEVICE FOR IDENTIFYING ELECTRODE COMBINATIONS IN NEUROSTIMULATION THERAPY
EP4406589A3 (en) Method for adjusting a system for stimulating a hypoglossal nerve
MX2016013910A (en) Cancer treatment.
WO2015014794A8 (en) Use of alpha-crystallin b (cryab) in the assessment of heart failure
WO2017216323A3 (en) Marker sequences for managing the therapy of rheumatoid arthritis patients
GB2552271A (en) A method for diagnosing lung cancer
WO2015169973A3 (en) Marker sequences for diagnosing and stratifying systemic sclerosis patients
WO2015125027A3 (en) Kit and method for detecting bladder cancer
WO2019066617A3 (en) Anti-c-met antibody and uses thereof
WO2021062085A8 (en) Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
WO2014023808A3 (en) Method for evaluating a cancer patient for propensity to respond to a therapy
HK1140797A1 (en) Matrix marker model and methods for assessing and treating rheumatoid arthritis
EP2846285A3 (en) Risk stratification of suspected AMI patients
WO2012129395A3 (en) Diagnosis and treatment of prostate cancer
WO2017053763A3 (en) ANDROGEN RECEPTOR VARIANT 7 AS A BIOMARKER FOR TREATMENT SELECTION IN PATIENTS WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER (mCRPC)
WO2018200473A8 (en) Detection and targeting of tumor-promoting neutrophils
WO2014042148A8 (en) Cancer marker and application thereof