IN2014DN08495A - - Google Patents

Info

Publication number
IN2014DN08495A
IN2014DN08495A IN8495DEN2014A IN2014DN08495A IN 2014DN08495 A IN2014DN08495 A IN 2014DN08495A IN 8495DEN2014 A IN8495DEN2014 A IN 8495DEN2014A IN 2014DN08495 A IN2014DN08495 A IN 2014DN08495A
Authority
IN
India
Prior art keywords
treatment
atypical antipsychotic
disorders amenable
amenable
disorders
Prior art date
Application number
Inventor
Deepak Phadke
Curt D Wolfgang
Mihael H Polymeropoulos
John Joseph Feeney
Gunther Birznieks
Original Assignee
Vanda Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48407766&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014DN08495(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vanda Pharmaceuticals Inc filed Critical Vanda Pharmaceuticals Inc
Publication of IN2014DN08495A publication Critical patent/IN2014DN08495A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

R P88 is used for the treatment of disorders amenable to treatment with an atypical antipsychotic.
IN8495DEN2014 2012-03-14 2013-03-14 IN2014DN08495A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261610664P 2012-03-14 2012-03-14
PCT/US2013/031413 WO2013138602A1 (en) 2012-03-14 2013-03-14 An iloperidone metabolite for use in the treatment of psychiatric disorders

Publications (1)

Publication Number Publication Date
IN2014DN08495A true IN2014DN08495A (en) 2015-05-08

Family

ID=48407766

Family Applications (1)

Application Number Title Priority Date Filing Date
IN8495DEN2014 IN2014DN08495A (en) 2012-03-14 2013-03-14

Country Status (17)

Country Link
US (3) US10874659B2 (en)
EP (2) EP3345603B1 (en)
JP (5) JP2015510893A (en)
KR (2) KR20170008327A (en)
CN (2) CN108938632A (en)
AU (2) AU2013232014B2 (en)
BR (1) BR112014022687A8 (en)
CA (1) CA2865845C (en)
CL (1) CL2014002430A1 (en)
CO (1) CO7091183A2 (en)
ES (2) ES2773711T3 (en)
IL (1) IL234412B (en)
IN (1) IN2014DN08495A (en)
MX (1) MX374067B (en)
RU (1) RU2651710C2 (en)
WO (1) WO2013138602A1 (en)
ZA (1) ZA201406369B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2870498T3 (en) 2015-02-17 2021-10-27 Vanda Pharmaceuticals Inc Iloperidone for the treatment of schizophrenia
US11214827B2 (en) * 2018-08-30 2022-01-04 Vanda Pharmaceuticals Inc. Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone
JP2026504721A (en) 2022-12-19 2026-02-09 バンダ・ファーマシューティカルズ・インコーポレイテッド Dosage regimen of iloperidone for the treatment of bipolar I disorder and schizophrenia
WO2024249952A1 (en) * 2023-06-02 2024-12-05 Vanda Pharmaceuticals Inc. Method of treatment with iloperidone

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US7029694B2 (en) 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
DK2305656T3 (en) 2001-08-31 2013-02-11 Novartis Ag Optical isomers or a iloperidone metabolite
PT1458888E (en) 2001-12-10 2011-06-01 Novartis Ag Methods of treating psychosis and schizophrenia based on polymorphisms in the cntf gene
TW200410955A (en) 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
GB0322994D0 (en) * 2003-10-01 2003-11-05 Novartis Ag Organic compounds
CA3113166A1 (en) 2004-09-30 2006-04-13 Vanda Pharmaceuticals Inc. Methods for the administration of iloperidone
US20100063093A1 (en) * 2007-03-28 2010-03-11 Curt Wolfgang Methods for the administration of iloperidone
AU2007253684A1 (en) * 2006-05-22 2007-11-29 Vanda Pharmaceuticals, Inc. Treatment for depressive disorders
EP2134873B1 (en) 2007-03-29 2015-05-06 Vanda Pharmaceuticals Inc. Method of predicting a predisposition to qt prolongation
EP2198048A2 (en) 2007-09-10 2010-06-23 Vanda Pharmaceuticals Inc. Prediction of qt prolongation based on snp genotype
WO2009036056A1 (en) 2007-09-10 2009-03-19 Vanda Pharmaceuticals, Inc. Antipsychotic treatment based on snp genotype
CA2757723C (en) 2009-04-06 2018-07-24 Vanda Pharmaceuticals, Inc. Method of predicting a predisposition to qt prolongation based on abcc2 gene sequence or product thereof
HUE037724T2 (en) 2009-04-06 2018-09-28 Vanda Pharmaceuticals Inc Method of treatment based on polymorphisms of the kcnq1 gene
EP2417266B1 (en) 2009-04-06 2016-03-09 Vanda Pharmaceuticals Inc. Method of predicting a predisposition to qt prolongation
US9072742B2 (en) 2009-04-06 2015-07-07 Vanda Pharmaceuticals, Inc. Method of predicting a predisposition to QT prolongation
CA2760474C (en) 2009-05-15 2020-08-18 Vanda Pharmaceuticals Inc. Antipsychotic treatment based on drd2 or ankk1 snp genotype

Also Published As

Publication number Publication date
JP2021001221A (en) 2021-01-07
ES2677474T3 (en) 2018-08-02
BR112014022687A2 (en) 2017-06-20
JP2017061506A (en) 2017-03-30
US20210015809A1 (en) 2021-01-21
US20150045390A1 (en) 2015-02-12
EP2825167B1 (en) 2018-05-09
KR20140121487A (en) 2014-10-15
EP3345603B1 (en) 2019-12-18
JP2015510893A (en) 2015-04-13
CN104203240A (en) 2014-12-10
JP2023022243A (en) 2023-02-14
CO7091183A2 (en) 2014-10-21
AU2013232014A1 (en) 2014-09-18
US10874659B2 (en) 2020-12-29
AU2016203591A1 (en) 2016-06-16
ES2773711T3 (en) 2020-07-14
KR20170008327A (en) 2017-01-23
JP2018203774A (en) 2018-12-27
IL234412B (en) 2018-04-30
CN108938632A (en) 2018-12-07
WO2013138602A1 (en) 2013-09-19
ZA201406369B (en) 2023-10-25
RU2651710C2 (en) 2018-04-23
EP3345603A1 (en) 2018-07-11
AU2016203591B2 (en) 2018-03-08
RU2014141112A (en) 2016-05-10
US20240016791A1 (en) 2024-01-18
CA2865845A1 (en) 2013-09-19
JP7151029B2 (en) 2022-10-12
CL2014002430A1 (en) 2015-04-17
MX2014010989A (en) 2015-03-10
MX374067B (en) 2020-07-30
CA2865845C (en) 2020-02-18
BR112014022687A8 (en) 2021-07-06
AU2013232014B2 (en) 2016-06-16
EP2825167A1 (en) 2015-01-21

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