IN2014DN07247A - - Google Patents

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Publication number
IN2014DN07247A
IN2014DN07247A IN7247DEN2014A IN2014DN07247A IN 2014DN07247 A IN2014DN07247 A IN 2014DN07247A IN 7247DEN2014 A IN7247DEN2014 A IN 7247DEN2014A IN 2014DN07247 A IN2014DN07247 A IN 2014DN07247A
Authority
IN
India
Prior art keywords
methods
individual
health
state
ratio data
Prior art date
Application number
Inventor
Hamid R Eghbalnia
Mark E Cook
Warren Paul Porter
Daniel Elmer Butz
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IN2014DN07247A publication Critical patent/IN2014DN07247A/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412—Detecting or monitoring sepsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4845—Toxicology, e.g. by detection of alcohol, drug or toxic products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4842—Monitoring progression or stage of a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The methods described herein are based on the observation that oscillations in breath isotope ratio data can be used for the purpose of identifying an 'unhealthy' state in an organism such as a human. Described herein are methods of determining the state of health of an individual such as the transition from healthy to infected by identifying changes in oscillation modes in breath isotope ratio data. Changes in the frequency and/or amplitude of the oscillation modes are correlated with the heath of the individual. The methods can advantageously be used to provide information about the health of an individual in shorter periods of time than previous methods.
IN7247DEN2014 2012-03-07 2013-01-07 IN2014DN07247A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/414,061 US8512676B1 (en) 2012-03-07 2012-03-07 Detection of rate changes in systematic oscillations of metabolic athways by monitoring isotope ratios
PCT/US2013/020496 WO2013133904A2 (en) 2012-03-07 2013-01-07 Detection of rate changes in systematic oscillations of metabolic pathways by monitoring isotope ratios

Publications (1)

Publication Number Publication Date
IN2014DN07247A true IN2014DN07247A (en) 2015-04-24

Family

ID=47628440

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7247DEN2014 IN2014DN07247A (en) 2012-03-07 2013-01-07

Country Status (8)

Country Link
US (1) US8512676B1 (en)
EP (1) EP2839277A2 (en)
JP (1) JP6396218B2 (en)
CN (1) CN104272107B (en)
AU (1) AU2013230841B2 (en)
CA (1) CA2865492C (en)
IN (1) IN2014DN07247A (en)
WO (1) WO2013133904A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104458603A (en) * 2013-09-23 2015-03-25 苏州青山生物科技有限公司 Novel helicobacter pylori detection method and device as well as application thereof
US20150196248A1 (en) 2014-01-10 2015-07-16 The United States Of America, As Represented By The Secretary Of Agriculture Methods of determining energy balance using breath carbon isotope ratios
US10226484B2 (en) 2014-12-01 2019-03-12 Peter Y Novak Pharmaceutical composition for improving health, cure abnormalities and degenerative disease, achieve anti-aging effect of therapy and therapeutic effect on mammals and method thereof
US10165965B1 (en) 2015-10-22 2019-01-01 Roy Pinchot Noninvasive method for measuring lactic acid and detection of anaerobic exercise for evaluating fitness
CN105954504B (en) * 2016-06-01 2018-10-26 苏州科技学院 Quick alcohol determining signal processing method and preliminary survey device
US10183041B2 (en) 2017-04-12 2019-01-22 Vector Vitale Ip Llc Antibacterial composition and its use in treating bacterial infections
US11484610B2 (en) 2019-11-22 2022-11-01 Vector Vitale Ip Llc Method of treating melanoma
US10799530B1 (en) 2019-12-20 2020-10-13 Vector Vitale Ip Llc Composition and method for the prevention and treatment of obesity
US11596650B2 (en) 2019-12-20 2023-03-07 Vector Vitale Ip Llc Composition and method for the treatment of type 2 diabetes
US10933091B1 (en) 2019-12-20 2021-03-02 Vector Vitale Ip Llc Composition and method for the treatment of type I diabetes
JP7718650B2 (en) * 2021-05-19 2025-08-05 国立大学法人東北大学 Infectious disease biomarkers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912178A (en) * 1994-02-16 1999-06-15 Wisconsin Alumni Research Foundation Passive measurement of isotopes to monitor health
JPH1087512A (en) * 1996-09-18 1998-04-07 Isao Nishi Method for real-time inspection of helicobacter pylori infection through urea reagent labeled with 13c
US6609068B2 (en) * 2000-02-22 2003-08-19 Dow Global Technologies Inc. Personal computer breath analyzer for health-related behavior modification and method
GB0120027D0 (en) * 2001-08-16 2001-10-10 Isis Innovation Spectroscopic breath analysis
US8512258B2 (en) * 2005-11-11 2013-08-20 Exalenz Bioscience Ltd. Breath test device and method
EP1960004A4 (en) * 2005-11-11 2011-04-20 Breathid 2006 Breath test device and method
US7465276B2 (en) * 2005-11-30 2008-12-16 Wisconsin Alumni Research Foundation Identification of disease characteristics using isotope ratios in breath
EP2092304A4 (en) * 2006-12-18 2013-04-17 Picomole Instr Inc Apparatus and method for rapid and accurate quantification of an unknown, complex mixture
US8026049B2 (en) * 2007-03-23 2011-09-27 Wisconsin Alumni Research Foundation Noninvasive measurement and identification of biomarkers in disease state
CA2715157C (en) * 2008-02-15 2015-05-12 The Science And Technology Facilities Council Infrared spectrometer
DE102009055321B4 (en) * 2009-12-24 2013-04-18 Humedics Gmbh Method for determining the liver performance of a living organism by means of quantitative measurement of the metabolism of substrates

Also Published As

Publication number Publication date
CA2865492C (en) 2021-06-01
AU2013230841A1 (en) 2014-09-11
JP6396218B2 (en) 2018-09-26
EP2839277A2 (en) 2015-02-25
US8512676B1 (en) 2013-08-20
CN104272107A (en) 2015-01-07
CN104272107B (en) 2017-05-17
AU2013230841B2 (en) 2018-09-27
WO2013133904A2 (en) 2013-09-12
JP2015511009A (en) 2015-04-13
CA2865492A1 (en) 2013-09-12
US20130236925A1 (en) 2013-09-12

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