IN2014DN06807A - - Google Patents

Info

Publication number
IN2014DN06807A
IN2014DN06807A IN6807DEN2014A IN2014DN06807A IN 2014DN06807 A IN2014DN06807 A IN 2014DN06807A IN 6807DEN2014 A IN6807DEN2014 A IN 6807DEN2014A IN 2014DN06807 A IN2014DN06807 A IN 2014DN06807A
Authority
IN
India
Prior art keywords
glycerol
transporter polypeptides
bacteria
variant
sucrose transporter
Prior art date
Application number
Inventor
Dana M Walters Pollak
Tina K Van Dyk
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IN2014DN06807A publication Critical patent/IN2014DN06807A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C12P7/20—Glycerol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Variant sucrose transporter polypeptides that enable bacterial growth over a wide range of gene expression levels and sucrose concentrations are described. Additionally recombinant bacteria comprising these variant sucrose transporter polypeptides and methods of utilizing the bacteria to produce products such as glycerol and glycerol derived products are provided.
IN6807DEN2014 2012-03-05 2013-03-05 IN2014DN06807A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/412,124 US8686114B2 (en) 2012-03-05 2012-03-05 Variant sucrose transporter polypeptides
PCT/US2013/028958 WO2013134167A1 (en) 2012-03-05 2013-03-05 Variant sucrose transporter polypeptides

Publications (1)

Publication Number Publication Date
IN2014DN06807A true IN2014DN06807A (en) 2015-05-22

Family

ID=47884597

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6807DEN2014 IN2014DN06807A (en) 2012-03-05 2013-03-05

Country Status (10)

Country Link
US (3) US8686114B2 (en)
EP (1) EP2822959A1 (en)
JP (1) JP2015509378A (en)
KR (1) KR20140135803A (en)
CN (1) CN104245723A (en)
AU (1) AU2013230227A1 (en)
CA (1) CA2866374A1 (en)
IN (1) IN2014DN06807A (en)
SG (1) SG11201405095QA (en)
WO (1) WO2013134167A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
WO2022129470A1 (en) 2020-12-18 2022-06-23 Inbiose N.V. Variant sucrose permease polypeptides
CN114231509B (en) * 2021-12-31 2023-07-25 南京诺云生物科技有限公司 Sucrose phosphorylase and glucosyl glycerol production process
WO2024248535A1 (en) * 2023-06-02 2024-12-05 아주대학교산학협력단 Glycerol dehydratase variant and use thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DE69739715D1 (en) 1996-11-13 2010-02-04 Du Pont PREPARATION OF 1,3-PROPANGLIUM BY RECOMBINANT ORGANISMS
CA2311601C (en) 1997-12-02 2008-07-08 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
US7041814B1 (en) 1998-02-18 2006-05-09 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Enterobacter cloacae for diagnostics and therapeutics
US6610836B1 (en) 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics
ATE335823T1 (en) 1999-08-18 2006-09-15 Du Pont METHOD FOR THE BIOLOGICAL PRODUCTION OF 1,3-PROPANEDIOL
RU2212447C2 (en) 2000-04-26 2003-09-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Strain escherichia coli as producer of amino acid (variants) and method for preparing amino acid (variants)
EP1227152A1 (en) 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Bacterial strain and genome of bifidobacterium
JP3889650B2 (en) 2002-03-28 2007-03-07 三洋電機株式会社 Image processing method, image processing apparatus, computer program, and recording medium
EP2374879A3 (en) 2002-04-22 2012-01-11 E. I. du Pont de Nemours and Company Promoter and plasmid system for genetic engineering
CA2501574C (en) 2002-10-04 2013-12-03 E. I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
AU2008339217A1 (en) 2007-12-18 2009-06-25 Korea Advanced Institute Of Science And Technology Recombinant microorganism having an ability of using sucrose as a carbon source
DK2346999T3 (en) 2008-11-07 2013-09-30 Metabolic Explorer Sa Use of sucrose as a substrate for fermentation production of 1,2-propanediol
KR101083136B1 (en) 2009-02-13 2011-11-11 씨제이제일제당 (주) Microorganisms for producing l-amino acids and process for producing l-amino acids using them
KR101058893B1 (en) 2009-03-03 2011-08-23 씨제이제일제당 (주) L-amino acid producing microorganisms and L-amino acid production method using the same
KR101058894B1 (en) 2009-03-03 2011-08-23 씨제이제일제당 (주) L-amino acid producing microorganisms and L-amino acid production method using the same
US20110144377A1 (en) 2009-06-16 2011-06-16 E. I. Du Pont Nemours And Company Process for the biological production of 3-hydroxypropionic acid with high yield
US20110136190A1 (en) 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
DE102010029973A1 (en) * 2010-06-11 2011-12-15 Evonik Degussa Gmbh Microbiological production of C4 bodies from sucrose and carbon dioxide
US8222000B2 (en) 2010-12-06 2012-07-17 E I Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
US8673602B2 (en) * 2011-08-16 2014-03-18 E I Du Pont De Nemours And Company Recombinant bacteria having improved sucrose utilization
US8629243B2 (en) * 2011-08-16 2014-01-14 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria

Also Published As

Publication number Publication date
CN104245723A (en) 2014-12-24
SG11201405095QA (en) 2014-09-26
WO2013134167A1 (en) 2013-09-12
JP2015509378A (en) 2015-03-30
KR20140135803A (en) 2014-11-26
US20140147899A1 (en) 2014-05-29
AU2013230227A1 (en) 2014-08-28
EP2822959A1 (en) 2015-01-14
US20130230892A1 (en) 2013-09-05
US20140155578A1 (en) 2014-06-05
US8686114B2 (en) 2014-04-01
CA2866374A1 (en) 2013-09-12

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