IN2014DN03464A - - Google Patents
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- Publication number
- IN2014DN03464A IN2014DN03464A IN3464DEN2014A IN2014DN03464A IN 2014DN03464 A IN2014DN03464 A IN 2014DN03464A IN 3464DEN2014 A IN3464DEN2014 A IN 3464DEN2014A IN 2014DN03464 A IN2014DN03464 A IN 2014DN03464A
- Authority
- IN
- India
- Prior art keywords
- providing neuroprotection
- stroke
- mirna
- administering
- variant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
- C12N2310/141—MicroRNAs, miRNAs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3231—Chemical structure of the sugar modified ring structure having an additional ring, e.g. LNA, ENA
Abstract
The invention relates to a method for providing neuroprotection comprising administering to a subject an effective amount of a miRNA or a variant thereof. By providing neuroprotection stroke or ischemic stroke can be prevented and/or treated.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161555152P | 2011-11-03 | 2011-11-03 | |
PCT/US2012/063604 WO2013067531A2 (en) | 2011-11-03 | 2012-11-05 | Methods of using microrna 195 in providing neuroprotection |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN03464A true IN2014DN03464A (en) | 2015-06-05 |
Family
ID=48193054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3464DEN2014 IN2014DN03464A (en) | 2011-11-03 | 2012-11-05 |
Country Status (7)
Country | Link |
---|---|
US (1) | US9315812B2 (en) |
EP (1) | EP2773381B1 (en) |
JP (1) | JP5888572B2 (en) |
CN (1) | CN104080910A (en) |
IN (1) | IN2014DN03464A (en) |
TW (1) | TWI462741B (en) |
WO (1) | WO2013067531A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2916989A1 (en) * | 2013-06-28 | 2014-12-31 | London Health Sciences Centre Research Inc. | Inhibition of microrna for treatment of sepsis |
CN106474549B (en) | 2016-11-21 | 2019-05-03 | 南通大学 | The novel tissue tissue-engineered nerve of MicroRNA gene mediated constructs and its in the application for repairing neurologic defect |
WO2018111784A1 (en) * | 2016-12-14 | 2018-06-21 | China Medical University | Micro-rna-195 compositions and therapeutic use in ocular diseases |
EP4100021A4 (en) * | 2020-02-03 | 2023-11-15 | Rutgers, the State University of New Jersey | Microrna-7 compositions for promoting functional recovery following spinal cord injury and methods of use thereof |
WO2022033529A1 (en) * | 2020-08-12 | 2022-02-17 | 洪明奇 | Use of sema3d antagonist in preventing or treating neurodegenerative diseases and prolonging lifespan |
CN113599540B (en) * | 2021-05-27 | 2023-05-23 | 山西医科大学 | Application of miRNA-195-5p in preparation of reagent for inhibiting or reducing nerve cell damage caused by aluminum maltol |
CN113308535A (en) * | 2021-06-11 | 2021-08-27 | 中国人民解放军空军军医大学 | PD diagnosis and staging kit based on serum exosome miRNA |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
CA2533701A1 (en) | 2003-07-31 | 2005-02-17 | Isis Pharmaceuticals, Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding rnas |
WO2005078139A2 (en) * | 2004-02-09 | 2005-08-25 | Thomas Jefferson University | DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES |
EP2111408A4 (en) * | 2007-01-17 | 2010-02-03 | Univ Johns Hopkins | Compositions and methods featuring micronas for treating neoplasia |
AU2008323652B2 (en) * | 2007-11-09 | 2014-02-20 | Board Of Regents, The University Of Texas System | Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair |
US20110117111A1 (en) | 2008-03-26 | 2011-05-19 | Johns Hopkins University | Microrna-based diagnostic testing and therapies for inflammatory bowel disease and related diseases |
EP2112235A1 (en) * | 2008-04-24 | 2009-10-28 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Compositions and methods for microRNA expression profiling of nasopharyngeal carcinoma |
EP2239675A1 (en) * | 2009-04-07 | 2010-10-13 | BIOCRATES Life Sciences AG | Method for in vitro diagnosing a complex disease |
US8486909B2 (en) | 2009-06-24 | 2013-07-16 | Board Of Regents Of The University Of Nebraska | Compositions and methods for the diagnosis and treatment of inflammatory disorders and fibrotic disease |
US8354520B2 (en) * | 2009-12-10 | 2013-01-15 | Kaohsiung Medical University | Composition and method for treating atherosclerosis, method for determining if a subject has atherosclerosis and method of screening an anti-atherosclerotic drug |
-
2012
- 2012-11-05 TW TW101141016A patent/TWI462741B/en not_active IP Right Cessation
- 2012-11-05 EP EP12845133.3A patent/EP2773381B1/en active Active
- 2012-11-05 JP JP2014540189A patent/JP5888572B2/en not_active Expired - Fee Related
- 2012-11-05 CN CN201280053577.8A patent/CN104080910A/en active Pending
- 2012-11-05 WO PCT/US2012/063604 patent/WO2013067531A2/en active Application Filing
- 2012-11-05 US US14/354,928 patent/US9315812B2/en active Active
- 2012-11-05 IN IN3464DEN2014 patent/IN2014DN03464A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013067531A2 (en) | 2013-05-10 |
JP5888572B2 (en) | 2016-03-22 |
US20140294943A1 (en) | 2014-10-02 |
EP2773381A4 (en) | 2015-07-08 |
WO2013067531A3 (en) | 2014-07-03 |
EP2773381B1 (en) | 2020-06-03 |
TWI462741B (en) | 2014-12-01 |
CN104080910A (en) | 2014-10-01 |
EP2773381A2 (en) | 2014-09-10 |
JP2014533248A (en) | 2014-12-11 |
TW201322987A (en) | 2013-06-16 |
US9315812B2 (en) | 2016-04-19 |
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