IN2014DN03429A - - Google Patents

Info

Publication number
IN2014DN03429A
IN2014DN03429A IN3429DEN2014A IN2014DN03429A IN 2014DN03429 A IN2014DN03429 A IN 2014DN03429A IN 3429DEN2014 A IN3429DEN2014 A IN 3429DEN2014A IN 2014DN03429 A IN2014DN03429 A IN 2014DN03429A
Authority
IN
India
Prior art keywords
inhibitor
matrix
allergene
whereon
adsorbed
Prior art date
Application number
Inventor
Thomas Grunwald
WEBER Carsten B SCHMIDT
Original Assignee
Pls Design Gmbh
Helmholtz Zentrum München Forschungszentrum Für Gesundheit Und Umwelt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pls Design Gmbh, Helmholtz Zentrum München Forschungszentrum Für Gesundheit Und Umwelt Gmbh filed Critical Pls Design Gmbh
Publication of IN2014DN03429A publication Critical patent/IN2014DN03429A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2026—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a pharmaceutical composition made of one or more preparations and comprising a physiologically effective dose of at least one IL 4 and/or IL 13 inhibitor and at least one allergene and a matrix wherein at least the inhibitor is solved or embedded or whereon at least the inhibitor is coated or adsorbed wherein the matrix is selected as to enable prolonged release of the inhibitor.
IN3429DEN2014 2011-11-23 2012-11-23 IN2014DN03429A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11075261.5A EP2596802A1 (en) 2011-11-23 2011-11-23 Pharmaceutical composition for treatment of allergic reactions
PCT/EP2012/004884 WO2013075846A1 (en) 2011-11-23 2012-11-23 Pharmaceutical composition for treatment of allergic reactions

Publications (1)

Publication Number Publication Date
IN2014DN03429A true IN2014DN03429A (en) 2015-06-05

Family

ID=47358079

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3429DEN2014 IN2014DN03429A (en) 2011-11-23 2012-11-23

Country Status (6)

Country Link
US (2) US20140335162A1 (en)
EP (1) EP2596802A1 (en)
CN (1) CN104039349A (en)
BR (1) BR112014012277A2 (en)
IN (1) IN2014DN03429A (en)
WO (1) WO2013075846A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2813242A1 (en) * 2013-06-13 2014-12-17 PLS-Design GmbH Low molecular weight immune-modulators as adjuvants for specific immunotherapy
EP2918262B1 (en) * 2014-03-10 2023-08-09 PLS-Design GmbH Induction of antigen-specific tolerance by peripheral phagocytosis
KR102825102B1 (en) * 2014-12-24 2025-06-26 넥스이뮨, 인크. Nanoparticle compositions and methods for immunotherapy
CN105727371B (en) * 2016-01-25 2019-04-09 北京天助畅运医疗技术股份有限公司 Ventral hernia repair material
KR102460040B1 (en) 2016-04-27 2022-11-01 애브비 인코포레이티드 Method for treating diseases in which IL-13 activity is detrimental using anti-IL-13 antibody
CN107669638B (en) * 2017-10-23 2020-05-22 华南理工大学 A kind of PEG-PCL-PEG triblock copolymer modified madecassoside liposome and its application
KR20230005880A (en) * 2020-04-22 2023-01-10 킨드레드 바이오사이언시스, 인코포레이티드 IL4/IL13 Receptor Molecule for Veterinary Use

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU643427B2 (en) 1988-10-31 1993-11-18 Immunex Corporation Interleukin-4 receptors
US5126147A (en) * 1990-02-08 1992-06-30 Biosearch, Inc. Sustained release dosage form
DE4137333A1 (en) 1991-11-13 1993-05-19 W Prof Dr Sebald THERAPEUTIC AGENTS THAT ARE ANTAGONISTS OR PARTIAL AGONISTS OF THE HUMAN INTERLEUKIN 4 OR CONTAIN THEM, HIL-4-MUTANT PROTEINS AND METHOD FOR THE PRODUCTION THEREOF
RU2235728C2 (en) 1996-06-14 2004-09-10 Байер Корпорэйшн Human il-4 mutein, polynucleotide molecule, vector, strain sf9 transformed with vector, method for selection of mutein, pharmaceutical composition for activation of t cells, method for treatment of patient suffering with disease and susceptible for treatment with il-4
US6028176A (en) 1996-07-19 2000-02-22 Bayer Corporation High-affinity interleukin-4 muteins
ATE290037T1 (en) 1997-10-03 2005-03-15 Macromed Inc BIODEGRADABLE TRIBLOCK POLY(LACTIDE-CO-GLYCOLIDE) POLYETHYLENE GLYCOL COPOLYMERS WITH REVERSE THERMAL GELATION
AU756951B2 (en) * 1998-03-02 2003-01-30 Applied Vaccine Technologies Corp. Methods and devices for modulating the immune response
IL138207A0 (en) * 1998-03-02 2001-10-31 Applied Vaccine Technologies C Methods and devices for modulating the immune response
US6841617B2 (en) * 2000-09-28 2005-01-11 Battelle Memorial Institute Thermogelling biodegradable aqueous polymer solution
US6451346B1 (en) * 1998-12-23 2002-09-17 Amgen Inc Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
AU4139801A (en) * 1999-12-06 2001-06-12 Board Of Trustees Of The University Of Arkansas, The Controlled delivery of antigens
MXPA02011682A (en) 2000-05-26 2003-05-14 Immunex Corp Use of interleukin-4 antagonists and compositions thereof.
AU2001273413A1 (en) 2000-07-12 2002-01-21 Immunex Corporation Method for treating cancer using an interleukin- 4 antagonist
US20030003074A1 (en) 2001-06-14 2003-01-02 Macromed, Inc. Formulations of lymphokines and method of use thereof for local or both local and systemic control of proliferative cell disorders
DE602005003374T2 (en) 2005-10-17 2008-09-11 Pls-Design Gmbh Method for the determination of an unknown PNS sequence and its uses
JP2009525267A (en) * 2006-01-11 2009-07-09 アエロヴァンス インコーポレイティッド Methods and compositions for treating asthma in humans and non-human primates
CA2917512C (en) * 2007-10-12 2025-08-05 President And Fellows Of Harvard College Vaccine nanotechnology
EP2245064B1 (en) 2007-12-21 2014-07-23 Medimmune Limited BINDING MEMBERS FOR INTERLEUKIN-4 RECEPTOR ALPHA (IL-4Ralpha)
TWI468191B (en) * 2009-01-28 2015-01-11 Novartis Ag Formulations of organic compounds
JP5656370B2 (en) 2009-07-01 2015-01-21 キヤノン株式会社 Image processing apparatus, image processing system, image processing method, and program

Also Published As

Publication number Publication date
US20140335162A1 (en) 2014-11-13
CN104039349A (en) 2014-09-10
WO2013075846A1 (en) 2013-05-30
US20180117143A1 (en) 2018-05-03
BR112014012277A2 (en) 2019-09-24
EP2596802A1 (en) 2013-05-29

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