IN2014DN02047A - - Google Patents

Info

Publication number
IN2014DN02047A
IN2014DN02047A IN2047DEN2014A IN2014DN02047A IN 2014DN02047 A IN2014DN02047 A IN 2014DN02047A IN 2047DEN2014 A IN2047DEN2014 A IN 2047DEN2014A IN 2014DN02047 A IN2014DN02047 A IN 2014DN02047A
Authority
IN
India
Prior art keywords
monomers
biocompatible
curable composition
vinyl ester
vinylcarbonate
Prior art date
Application number
Inventor
Robert Liska
Xiaohua Qin
Andreas Mautner
Original Assignee
Synthes Gmbh
Univ Wien Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes Gmbh, Univ Wien Tech filed Critical Synthes Gmbh
Publication of IN2014DN02047A publication Critical patent/IN2014DN02047A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L35/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L35/02—Homopolymers or copolymers of esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F18/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid or of a haloformic acid
    • C08F18/02—Esters of monocarboxylic acids
    • C08F18/04—Vinyl esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F18/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid or of a haloformic acid
    • C08F18/24—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F263/00—Macromolecular compounds obtained by polymerising monomers on to polymers of esters of unsaturated alcohols with saturated acids as defined in group C08F18/00
    • C08F263/02—Macromolecular compounds obtained by polymerising monomers on to polymers of esters of unsaturated alcohols with saturated acids as defined in group C08F18/00 on to polymers of vinyl esters with monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Thermal Sciences (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polymerisation Methods In General (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

The present disclosure is directed in part to a curable composition a method for augmenting a structure in a patient with a resorbable biocompatible polymer and a biodegradable resorbable implant comprising a biocompatible copolymer. An exemplary embodiment of the curable composition comprises (a) 60 wt.% to 95 wt.% of one or more vinyl ester monomers and/or vinylcarbonate monomers wherein said one or more vinyl ester monomers and/or vinylcarbonate monomers are respectively selected from compounds of the general formulas (I) and (II) below: wherein n m R and R have the meaning defined herein; (b) 0.1 to 40 wt.% of one or more multifunctional thiols; and (c) 0 to 10 wt.% of a biocompatible polymerization initiator.
IN2047DEN2014 2011-10-03 2012-09-26 IN2014DN02047A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161542522P 2011-10-03 2011-10-03
PCT/US2012/057295 WO2013052328A1 (en) 2011-10-03 2012-09-26 Thiol-ene polymerization with vinylesters and vinylcarbonate

Publications (1)

Publication Number Publication Date
IN2014DN02047A true IN2014DN02047A (en) 2015-05-15

Family

ID=47010781

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2047DEN2014 IN2014DN02047A (en) 2011-10-03 2012-09-26

Country Status (9)

Country Link
US (2) US9623145B2 (en)
EP (2) EP2764049B1 (en)
JP (1) JP6101271B2 (en)
KR (1) KR101964033B1 (en)
CN (2) CN103975014A (en)
BR (1) BR112014007993A2 (en)
CA (2) CA3004569A1 (en)
IN (1) IN2014DN02047A (en)
WO (1) WO2013052328A1 (en)

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EP2764049B1 (en) 2011-10-03 2016-08-17 Synthes GmbH Thiol-ene polymerization with vinylesters and vinylcarbonate
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US20160230014A1 (en) * 2013-09-13 2016-08-11 Basf Se Scratch-resistant radiation-cured coatings
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WO2015164524A1 (en) 2014-04-22 2015-10-29 Ariste Medical, Inc. Methods and processes for application of drug delivery polymeric coatings
CN106463678B (en) * 2014-05-30 2020-01-03 巴斯夫欧洲公司 Polymers for use as protective layers and other components in electrochemical cells
KR101597804B1 (en) * 2014-06-03 2016-02-25 포항공과대학교 산학협력단 Compound containing catechol and thiol group, and preparation method and use thereof
EP3237494B1 (en) 2014-12-23 2021-06-16 3M Innovative Properties Company Dual cure polythioether
US10492888B2 (en) * 2015-07-07 2019-12-03 Align Technology, Inc. Dental materials using thermoset polymers
KR20180095853A (en) 2015-12-16 2018-08-28 너바시브 인코퍼레이티드 Porous Spine Fusion Implant
TWI654246B (en) 2016-03-28 2019-03-21 國立陽明大學 Biodegradable and light-cured composition for three dimensional printing
TWI614280B (en) * 2016-03-28 2018-02-11 國立陽明大學 Light-cured biodegradable polymer and method for manufacturing thereof
JP6929930B2 (en) * 2016-07-14 2021-09-01 エスケーシー カンパニー，リミテッド Aromatic polythiol compounds for optical materials
EP3541440A1 (en) * 2016-11-16 2019-09-25 Ecole Polytechnique Federale de Lausanne (EPFL) Photopolymerizable bone filler material
US10851264B2 (en) * 2017-02-27 2020-12-01 Nufern Optical fiber coating composition
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JP7282105B2 (en) * 2018-05-15 2023-05-26 ボシュ・アンド・ロム・インコーポレイテッド Water extractable ophthalmic device
JP2021524395A (en) * 2018-05-22 2021-09-13 スリーエム イノベイティブ プロパティズ カンパニー Processing process of radiation-curable thiol-based composition using laminated molding technology
AU2019276160B2 (en) * 2018-05-31 2022-08-18 Universiteit Gent Bifunctional modified biopolymer based polymers and hydrogels obtainable from such bifunctional modified biopolymer based polymers
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CN109232839B (en) * 2018-08-06 2021-04-06 浙江工业大学 3D printing degradable material with photoresponse and preparation method thereof
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Also Published As

Publication number Publication date
CN110478526A (en) 2019-11-22
CN103975014A (en) 2014-08-06
US9623145B2 (en) 2017-04-18
KR101964033B1 (en) 2019-08-07
US20130084543A1 (en) 2013-04-04
CA2851060A1 (en) 2013-04-11
JP6101271B2 (en) 2017-03-22
EP3091050B1 (en) 2018-07-18
US9814801B2 (en) 2017-11-14
WO2013052328A1 (en) 2013-04-11
EP3091050A1 (en) 2016-11-09
EP2764049A1 (en) 2014-08-13
JP2014531503A (en) 2014-11-27
EP2764049B1 (en) 2016-08-17
KR20140076608A (en) 2014-06-20
CA2851060C (en) 2019-01-29
US20160243279A1 (en) 2016-08-25
CA3004569A1 (en) 2013-04-11
BR112014007993A2 (en) 2017-04-04

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