IN2014DE00820AIN820DE2014AIN2014DE00820AIN 2014DE00820 AIN2014DE00820 AIN 2014DE00820AIN 820DE2014 AIN820DE2014 AIN 820DE2014AIN 2014DE00820 AIN2014DE00820 AIN 2014DE00820A
Authority
IN
India
Prior art keywords
monoclonal antibody
shigella flexneri
present
seq
set forth
Prior art date
Application number
Inventor
Radhika Madan Urs
Venkataramana MUDILI
Shylaja Ramlal
Urmil TUTEJA
Harishchandra Sripathy Murali
Harsh Vardhan Batra
Original Assignee
Director General Defence Res And Dev Organization
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Publication date
Application filed by Director General Defence Res And Dev OrganizationfiledCriticalDirector General Defence Res And Dev Organization
Priority to IN820DE2014priorityCriticalpatent/IN2014DE00820A/en
Publication of IN2014DE00820ApublicationCriticalpatent/IN2014DE00820A/en
The present invention provides for a monoclonal antibody specific for Shigella flexneri and process for preparation thereof. The present invention discloses a monoclonal antibody generated against whole cell lysate of Shigella flexneri and a method of generating the same, wherein the monoclonal antibody comprises a heavy chain comprising a region as set forth in SEQ ID NO: 1 or a part thereof, and a light chain comprising a region as set forth in SEQ ID NO: 2 or a part thereof. The present invention also provides for dot ELISA method for specific detection of Shigella flexneri in contaminated food, environmental and/or clinical samples using the monoclonal antibody specific for Shigella flexneri.
anti-cd3 antibodies, isolated nucleic acid, vector, host cell, anti-cd3 antibody production method, immunoconjugate, composition, use of anti-cd3 antibody, treatment methods, methods of enhancing immune function and kit