IN2014CN03925A - - Google Patents
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- Publication number
- IN2014CN03925A IN2014CN03925A IN3925CHN2014A IN2014CN03925A IN 2014CN03925 A IN2014CN03925 A IN 2014CN03925A IN 3925CHN2014 A IN3925CHN2014 A IN 3925CHN2014A IN 2014CN03925 A IN2014CN03925 A IN 2014CN03925A
- Authority
- IN
- India
- Prior art keywords
- chimeric protein
- dengue virus
- create
- virus
- protein
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Described here is a method to produce a chimeric protein having portions of yellow fever virus and dengue virus. A small portion of the yellow fever virus 17D vaccine strain envelope protein (or other related flavivirus) can be replaced by the corresponding portion from the dengue virus envelope protein. In some embodiments the chimeric protein may be used to create a treatment composition for DENV infection. In others the chimeric protein may be used to create a vaccine that will induce broadly protective antibodies against dengue virus and reduce the induction of non neutralizing antibodies that will cause enhancement.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161550982P | 2011-10-25 | 2011-10-25 | |
PCT/US2012/061893 WO2013063248A1 (en) | 2011-10-25 | 2012-10-25 | Vaccines and methods for creating a vaccine for inducing immunity to all dengue virus serotypes |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN03925A true IN2014CN03925A (en) | 2015-07-03 |
Family
ID=48168485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3925CHN2014 IN2014CN03925A (en) | 2011-10-25 | 2012-10-25 |
Country Status (9)
Country | Link |
---|---|
US (2) | US20150265694A1 (en) |
EP (1) | EP2771366A4 (en) |
CN (1) | CN104736568A (en) |
BR (1) | BR112014009887A2 (en) |
CR (1) | CR20140189S (en) |
HK (2) | HK1198770A1 (en) |
IN (1) | IN2014CN03925A (en) |
SG (1) | SG11201401733VA (en) |
WO (1) | WO2013063248A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201404711WA (en) | 2012-02-16 | 2014-09-26 | Vlp Therapeutics Llc | Virus like particle composition |
TWI676636B (en) | 2013-07-12 | 2019-11-11 | Vlp醫療股份有限公司 | Virus like particle comprising pd-1 antigen or pd-1 ligand antigen |
US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
TWI720946B (en) | 2014-08-08 | 2021-03-11 | 美商Vlp醫療股份有限公司 | Virus like particle comprising modified envelope protein e3 |
AU2015313650B2 (en) * | 2014-09-11 | 2021-07-08 | Vlp Therapeutics, Inc. | Flavivirus virus like particle |
CN105732777B (en) * | 2016-05-05 | 2019-06-04 | 中国人民解放军军事医学科学院微生物流行病研究所 | Yellow fever virus specific detection antigen and its application |
WO2018208547A1 (en) * | 2017-05-10 | 2018-11-15 | University Of Massachusetts | Bivalent dengue/hepatitis b vaccines |
CN113429479B (en) * | 2018-04-04 | 2023-03-10 | 中国科学院微生物研究所 | High-sensitivity yellow fever virus humanized monoclonal antibody and application thereof |
CN109627294B (en) * | 2018-12-29 | 2020-10-09 | 四川大学 | Correctly folded recombinant rabies virus G protein extracellular domain and potential application thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2372991B (en) * | 2001-03-09 | 2004-11-17 | Fiocruz Fundacao Oswaldo Cruz | Flavivirus expression vector |
BR0210907A (en) * | 2001-06-01 | 2004-12-21 | Acambis Inc | Chimeric Flavivirus Vectors |
ZA200802176B (en) * | 2005-08-10 | 2009-08-26 | Acambis Inc | Vaccination against dengue virus infection |
-
2012
- 2012-10-25 WO PCT/US2012/061893 patent/WO2013063248A1/en active Application Filing
- 2012-10-25 IN IN3925CHN2014 patent/IN2014CN03925A/en unknown
- 2012-10-25 SG SG11201401733VA patent/SG11201401733VA/en unknown
- 2012-10-25 BR BR112014009887A patent/BR112014009887A2/en not_active IP Right Cessation
- 2012-10-25 CN CN201280052904.8A patent/CN104736568A/en active Pending
- 2012-10-25 US US13/660,653 patent/US20150265694A1/en not_active Abandoned
- 2012-10-25 EP EP12842872.9A patent/EP2771366A4/en not_active Withdrawn
-
2014
- 2014-04-25 CR CR20140189F patent/CR20140189S/en unknown
- 2014-12-05 HK HK14112282.6A patent/HK1198770A1/en unknown
-
2015
- 2015-07-21 HK HK15106951.7A patent/HK1206366A1/en unknown
-
2017
- 2017-01-23 US US15/413,347 patent/US10124053B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2771366A4 (en) | 2015-06-03 |
EP2771366A1 (en) | 2014-09-03 |
SG11201401733VA (en) | 2014-09-26 |
CN104736568A (en) | 2015-06-24 |
CR20140189S (en) | 2014-09-24 |
HK1198770A1 (en) | 2015-07-31 |
WO2013063248A1 (en) | 2013-05-02 |
US20150265694A1 (en) | 2015-09-24 |
US20170202945A1 (en) | 2017-07-20 |
HK1206366A1 (en) | 2016-01-08 |
US10124053B2 (en) | 2018-11-13 |
BR112014009887A2 (en) | 2017-04-25 |
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