IN2014CN03886A - - Google Patents
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- Publication number
- IN2014CN03886A IN2014CN03886A IN3886CHN2014A IN2014CN03886A IN 2014CN03886 A IN2014CN03886 A IN 2014CN03886A IN 3886CHN2014 A IN3886CHN2014 A IN 3886CHN2014A IN 2014CN03886 A IN2014CN03886 A IN 2014CN03886A
- Authority
- IN
- India
- Prior art keywords
- primycin
- antibotic
- mupirocin
- methicillin
- vancomycin
- Prior art date
Links
- NYWSLZMTZNODJM-MCGDBQAWSA-N 2-[5-[(4e,20e)-35-butyl-19-[(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-10,12,14,16,18,22,26,30,34-nonahydroxy-3,5,21,33-tetramethyl-36-oxo-1-oxacyclohexatriaconta-4,20-dien-2-yl]-4-hydroxyhexyl]guanidine Chemical compound OC1CC(O)CC(O)CC(O)CC(O)CCCC\C(C)=C\C(C)C(C(C)C(O)CCCN=C(N)N)OC(=O)C(CCCC)C(O)C(C)CCC(O)CCCC(O)CCCC(O)\C(C)=C\C1O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 NYWSLZMTZNODJM-MCGDBQAWSA-N 0.000 abstract 3
- 229950010664 primycin Drugs 0.000 abstract 3
- NYWSLZMTZNODJM-SDUQVVOESA-N primycin Natural products CCCC[C@H]1[C@H](O)[C@H](C)CC[C@@H](O)CCC[C@@H](O)CCC[C@@H](O)C(=C[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)C[C@H](O)CCCCC(=C[C@@H](C)[C@@H](OC1=O)[C@H](C)[C@H](O)CCCNC(=N)N)C)C NYWSLZMTZNODJM-SDUQVVOESA-N 0.000 abstract 3
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 108010059993 Vancomycin Proteins 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229960003085 meticillin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960003128 mupirocin Drugs 0.000 abstract 1
- 229930187697 mupirocin Natural products 0.000 abstract 1
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 abstract 1
- 229960003165 vancomycin Drugs 0.000 abstract 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention refers to primycin or a primycin component or a combination of primycin components for use in the treatment or prevention of infections caused by Gram positive bacteria resistant to methicillin and/or vancomycin and/or mupirocin or by penicillin resistant streptococci. The invention also covers antibotic compositions containing these active agents.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU1100597A HU230455B1 (en) | 2011-10-25 | 2011-10-25 | Primycin or its components or combination thereof for the treatment or prevention of infestations by special organisms |
| PCT/HU2012/000111 WO2013061101A1 (en) | 2011-10-25 | 2012-10-25 | Primycin and components thereof for use in the treatment or prevention of infections caused by specific pathogens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN03886A true IN2014CN03886A (en) | 2015-10-16 |
Family
ID=89990487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3886CHN2014 IN2014CN03886A (en) | 2011-10-25 | 2012-10-25 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20140303105A1 (en) |
| EP (1) | EP2771016B1 (en) |
| CA (1) | CA2853407C (en) |
| DK (1) | DK2771016T3 (en) |
| HR (1) | HRP20160833T1 (en) |
| HU (1) | HU230455B1 (en) |
| IN (1) | IN2014CN03886A (en) |
| PL (1) | PL2771016T3 (en) |
| SI (1) | SI2771016T1 (en) |
| WO (1) | WO2013061101A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112175027B (en) * | 2020-10-23 | 2021-10-22 | 中国医学科学院医药生物技术研究所 | Preparation method of oleanolic acid derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE756856A (en) | 1969-09-30 | 1971-03-01 | Chinoin Gyogyszer Es Vegyeszet | NEW ANTIBIOTIC COMPOSITIONS WITH AN INCREASED THERAPEUTIC EFFECT AND THEIR PREPARATION |
| US4404189A (en) | 1981-01-21 | 1983-09-13 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Synergistic antimicrobial compositions |
| CA1274508A (en) | 1984-05-31 | 1990-09-25 | Imre Szilagyi | Primycin components and process for the separation of the antibiotic complex |
| HU196425B (en) | 1984-07-26 | 1988-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing components of primicin and pharmaceutical compositions containing them |
| HU195514B (en) | 1984-05-31 | 1988-05-30 | Chinoin Gyogyszer Es Vegyeszet | Process for the digestion of triamycine, an antibioticcomplex |
| HU196822B (en) | 1984-07-03 | 1989-01-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing primicin salts |
| HU196309B (en) | 1985-05-29 | 1988-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing primicin |
| HU229804B1 (en) * | 2009-10-29 | 2014-07-28 | Pannonpharma Gyogyszergyarto Kft | Method of production of primycin, primycin components, and/or precursors and metabolites of primycin via fementation by the use of bacterial species saccharomonospora azurea |
-
2011
- 2011-10-25 HU HU1100597A patent/HU230455B1/en unknown
-
2012
- 2012-10-25 CA CA2853407A patent/CA2853407C/en not_active Expired - Fee Related
- 2012-10-25 US US14/353,800 patent/US20140303105A1/en not_active Abandoned
- 2012-10-25 PL PL12788250.4T patent/PL2771016T3/en unknown
- 2012-10-25 EP EP12788250.4A patent/EP2771016B1/en not_active Not-in-force
- 2012-10-25 DK DK12788250.4T patent/DK2771016T3/en active
- 2012-10-25 WO PCT/HU2012/000111 patent/WO2013061101A1/en active Application Filing
- 2012-10-25 SI SI201230625A patent/SI2771016T1/en unknown
- 2012-10-25 IN IN3886CHN2014 patent/IN2014CN03886A/en unknown
-
2016
- 2016-07-11 HR HRP20160833TT patent/HRP20160833T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2771016A1 (en) | 2014-09-03 |
| SI2771016T1 (en) | 2016-10-28 |
| DK2771016T3 (en) | 2016-08-01 |
| CA2853407C (en) | 2019-08-27 |
| EP2771016B1 (en) | 2016-04-20 |
| HRP20160833T1 (en) | 2016-09-23 |
| HUP1100597A2 (en) | 2013-04-29 |
| WO2013061101A1 (en) | 2013-05-02 |
| HU230455B1 (en) | 2016-07-28 |
| US20140303105A1 (en) | 2014-10-09 |
| CA2853407A1 (en) | 2013-05-02 |
| WO2013061101A9 (en) | 2013-06-06 |
| PL2771016T3 (en) | 2016-11-30 |
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