IN2014CH00475A - - Google Patents

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Publication number
IN2014CH00475A
IN2014CH00475A IN475CH2014A IN2014CH00475A IN 2014CH00475 A IN2014CH00475 A IN 2014CH00475A IN 475CH2014 A IN475CH2014 A IN 475CH2014A IN 2014CH00475 A IN2014CH00475 A IN 2014CH00475A
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IN
India
Prior art keywords
accurate
cervical
detecting
sandwich elisa
cervical cancer
Prior art date
Application number
Inventor
Rajkumar Dr Thangarajan
Mayil Vahanan Bose Mr
Original Assignee
Cancer Inst Wia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Inst Wia filed Critical Cancer Inst Wia
Priority to IN475CH2014 priority Critical patent/IN2014CH00475A/en
Publication of IN2014CH00475A publication Critical patent/IN2014CH00475A/en

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Abstract

TITLE: DETECTION OF CERVICAL PRE-CANCERS USING A NOVEL SANDWICH ELISA APPLICANT NAME: CANCER INSTITUTE ABSTRACT The present invention shall disclose an accurate and reliable method for the early detection of cervical cancer with minimal false result. The method involves collecting the cervical smear samples and detecting the presence of p16 in the collected samples by sandwich ELISA using novel monoclonal antibodies developed against recombinant p16 protein and detecting the presence of cytokeratin using direct ELISA to obtain p160D and cytokeratin OD. From the values of both the ODs the results were ascertained for the accurate presence or absence of cervical cancer. The invention also discloses the method of developing novel monoclonal antibodies against recombinant p16 protein for use in sandwich ELISA and thereby reliably detecting p16 even at 2 picogram level. The invention also discloses a kit for accurate, reliable and early detection of cervical cancer in a subject with minimal false results and avoiding the need for trained Pathologists or CytoPathologists or Cyto-Technologists.
IN475CH2014 2014-02-03 2014-02-03 IN2014CH00475A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN475CH2014 IN2014CH00475A (en) 2014-02-03 2014-02-03

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN475CH2014 IN2014CH00475A (en) 2014-02-03 2014-02-03

Publications (1)

Publication Number Publication Date
IN2014CH00475A true IN2014CH00475A (en) 2015-08-07

Family

ID=54393869

Family Applications (1)

Application Number Title Priority Date Filing Date
IN475CH2014 IN2014CH00475A (en) 2014-02-03 2014-02-03

Country Status (1)

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IN (1) IN2014CH00475A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110501497A (en) * 2019-08-28 2019-11-26 深圳市森盈生物科技有限公司 A kind of p16 cytochemical labeling colour reagent box

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110501497A (en) * 2019-08-28 2019-11-26 深圳市森盈生物科技有限公司 A kind of p16 cytochemical labeling colour reagent box

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