IN2014CH00304A - - Google Patents

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Publication number
IN2014CH00304A
IN2014CH00304A IN304CH2014A IN2014CH00304A IN 2014CH00304 A IN2014CH00304 A IN 2014CH00304A IN 304CH2014 A IN304CH2014 A IN 304CH2014A IN 2014CH00304 A IN2014CH00304 A IN 2014CH00304A
Authority
IN
India
Prior art keywords
preparation
trifluoroethanone
efavirenz
chlorophenyl
formula
Prior art date
Application number
Inventor
Gudla Dhanajaya
Rao Kota Kondala
Rao Ala Srinivasa
Manne Prashanth
Original Assignee
Discovery Intermediates Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Discovery Intermediates Pvt Ltd filed Critical Discovery Intermediates Pvt Ltd
Priority to PCT/IB2015/050533 priority Critical patent/WO2015111004A2/en
Priority to IN304CH2014 priority patent/IN2014CH00304A/en
Publication of IN2014CH00304A publication Critical patent/IN2014CH00304A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Abstract

The present invention relates to an improved process for the preparation of chlorophenyl trifluoroethanone of formula I, an intermediate used in the preparation of Efavirenz.
IN304CH2014 2014-01-24 2015-01-24 IN2014CH00304A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/IB2015/050533 WO2015111004A2 (en) 2014-01-24 2015-01-24 Improved process for the preparation of chlorophenyl trifluoroethanone
IN304CH2014 IN2014CH00304A (en) 2014-01-24 2015-01-24

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN304CH2014 IN2014CH00304A (en) 2014-01-24 2015-01-24

Publications (1)

Publication Number Publication Date
IN2014CH00304A true IN2014CH00304A (en) 2015-09-04

Family

ID=53682064

Family Applications (1)

Application Number Title Priority Date Filing Date
IN304CH2014 IN2014CH00304A (en) 2014-01-24 2015-01-24

Country Status (2)

Country Link
IN (1) IN2014CH00304A (en)
WO (1) WO2015111004A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105777610B (en) * 2015-10-16 2018-10-09 浙江沙星科技有限公司 A method of preparing 4- chloro- 2- (trifluoroacetyl group) anilinechloride hydrate
CN106518636A (en) * 2016-10-18 2017-03-22 浙江天宇药业股份有限公司 Method for preparing 4-chloro-2-(trifluoroacetyl)aniline hydrochloride hydrate and free alkalis thereof
CN108821938A (en) * 2018-08-06 2018-11-16 江苏沙星化工有限公司 It is a kind of to prepare the chloro- 2- of 4-（Trifluoroacetyl）The separation method of anilinechloride by-product
CN108997150B (en) * 2018-08-31 2021-01-12 江苏沙星化工有限公司 Preparation method of efavirenz intermediate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE527243T1 (en) * 2005-03-09 2011-10-15 Merck Sharp & Dohme CALCIUM CHANNEL ANTAGONISTS OF THE QUINAZOLINONE T TYPE

Also Published As

Publication number Publication date
WO2015111004A2 (en) 2015-07-30
WO2015111004A3 (en) 2017-05-11

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