IN2013MU03765AIN3765MU2013AIN2013MU03765AIN 2013MU03765 AIN2013MU03765 AIN 2013MU03765AIN 3765MU2013 AIN3765MU2013 AIN 3765MU2013AIN 2013MU03765 AIN2013MU03765 AIN 2013MU03765A
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IN
India
Prior art keywords
atorvastatin calcium
compositions
density lipoprotein
lipoprotein cholesterol
faster
Prior art date
Application number
Inventor
Gayatri Chhaganbhai Patel
Manali Manubhai Malaviya
Akash Rajendrakumar Patel
Brijesh Vallabhbhai Navadiya
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Charotar University Of Science & Technology
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Application filed by Charotar University Of Science & TechnologyfiledCriticalCharotar University Of Science & Technology
Priority to IN3765MU2013priorityCriticalpatent/IN2013MU03765A/en
Publication of IN2013MU03765ApublicationCriticalpatent/IN2013MU03765A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Abstract Solubilizing Compositions of Atorvastatin Calcium The present invention discloses solubilizing compositions of atorvastatin calcium which decrease low-density lipoprotein cholesterol (LDL-C) and increase high-density lipoprotein cholesterol (HDL-C). A pharmaceutical formulation of statin comprises of atorvastatin calcium, a non-aqueous vehicle, a binding agent, pharmaceutically acceptable excipients and an antioxidant. It reduces the risk for coronary heart diseases. It exerts faster dissolution in gastric fluid and leads to faster absorption which minimizes acid degradation of drug in the stomach. The compositions are formulated in the form of tablets and capsules.