IN2013MU03122A - - Google Patents

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Publication number
IN2013MU03122A
IN2013MU03122A IN3122MU2013A IN2013MU03122A IN 2013MU03122 A IN2013MU03122 A IN 2013MU03122A IN 3122MU2013 A IN3122MU2013 A IN 3122MU2013A IN 2013MU03122 A IN2013MU03122 A IN 2013MU03122A
Authority
IN
India
Prior art keywords
provides
present
levomilnacipran hydrochloride
amorphous form
levomilnacipran
Prior art date
Application number
Inventor
Shri Prakash Dhar Dwivedi
Brij Khera
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Priority to IN3122MU2013 priority Critical patent/IN2013MU03122A/en
Priority to PCT/IN2014/000632 priority patent/WO2015044962A1/en
Publication of IN2013MU03122A publication Critical patent/IN2013MU03122A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Abstract

ABSTRACT AMORPHOUS FORM OF LEVOMILNACIPRAN HYDROCHLORIDE AND HYDRATES THEREOF The present invention provides an amorphous form of levomilnacipran hydrochloride and process of preparation thereof. The present invention also provides an amorphous solid dispersion comprising levomilnacipran hydrochloride and a polymer.
IN3122MU2013 2013-09-30 2014-09-30 IN2013MU03122A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN3122MU2013 IN2013MU03122A (en) 2013-09-30 2014-09-30
PCT/IN2014/000632 WO2015044962A1 (en) 2013-09-30 2014-09-30 Amorphous form of levomilnacipran hydrochloride and hydrates thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3122MU2013 IN2013MU03122A (en) 2013-09-30 2014-09-30

Publications (1)

Publication Number Publication Date
IN2013MU03122A true IN2013MU03122A (en) 2015-07-17

Family

ID=52117937

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3122MU2013 IN2013MU03122A (en) 2013-09-30 2014-09-30

Country Status (2)

Country Link
IN (1) IN2013MU03122A (en)
WO (1) WO2015044962A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508035A1 (en) 1981-06-23 1982-12-24 Fabre Sa Pierre ARYL-1-AMINOMETHYL-2 CYCLOPROPANES CARBOXAMIDE (Z) DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
FR2851163B1 (en) 2003-02-14 2007-04-27 USE OF DEXTROGYAN ENANTIOMER OF MILNACIPRAN FOR THE PREPARATION OF A MEDICINAL PRODUCT
US7309799B2 (en) * 2004-06-01 2007-12-18 Collegium Pharmaceutical, Inc. Methods for the synthesis of milnacipran and congeners thereof
CA2779711C (en) 2009-11-06 2016-11-01 Forest Laboratories Holding Limited Novel crystalline forms of (1s,2r)-2-(amino methyl)-n,n-diethyl-1-phenyl cyclopropane carboxamide
WO2011158249A1 (en) * 2010-06-16 2011-12-22 Glenmark Generics Limited Process for preparation of milnacipran intermediate and its use in preparation of pure milnacipran
US20120289744A1 (en) * 2010-11-03 2012-11-15 Arch Pharmalabs Limited Process for preparing optically pure milnacipran and its pharmaceutically acceptable salts

Also Published As

Publication number Publication date
WO2015044962A1 (en) 2015-04-02

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