IN2013MU02723AIN2723MU2013AIN2013MU02723AIN 2013MU02723 AIN2013MU02723 AIN 2013MU02723AIN 2723MU2013 AIN2723MU2013 AIN 2723MU2013AIN 2013MU02723 AIN2013MU02723 AIN 2013MU02723A
Authority
IN
India
Prior art keywords
rivaroxaban
solvent
pharmaceutically accepted
purification
avoiding
Prior art date
Application number
Inventor
Sharadchandra Pradhan Dr Nitin
Sudhir Patil Dr Nilesh
Ramchandra Walavalkar Dr Rajesh
Nilesh Subhash Kulkarni Mr
Sandip Babanrao Pawar Mr
Original Assignee
Wanbury Ltd
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Filing date
Publication date
Application filed by Wanbury LtdfiledCriticalWanbury Ltd
Priority to IN2723MU2013priorityCriticalpatent/IN2013MU02723A/en
Publication of IN2013MU02723ApublicationCriticalpatent/IN2013MU02723A/en
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
This invention mainly relates to a process for the purification of rivaroxaban and its pharmaceutically accepted salts, wherein the crude rivaroxaban treated with an acid optionally, in presence of solvent to form clear solution which further precipitates out the pure rivaroxaban or its pharmaceutically accepted salt by adding anti-solvent. The obtained rivaroxaban having the desired purity with quality by avoiding any further purification