IN2013MU02699A - - Google Patents
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- Publication number
- IN2013MU02699A IN2013MU02699A IN2699MU2013A IN2013MU02699A IN 2013MU02699 A IN2013MU02699 A IN 2013MU02699A IN 2699MU2013 A IN2699MU2013 A IN 2699MU2013A IN 2013MU02699 A IN2013MU02699 A IN 2013MU02699A
- Authority
- IN
- India
- Prior art keywords
- rivaroxaban
- preparation
- isomeric
- intermediates
- advantage
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Described is an improved, industrially feasible and environmental friendly process for the preparation of Rivaroxaban. The process also has the advantage of avoiding formation of isomeric and process related impurities. Also described are novel compounds which are used as intermediates in preparation of Rivaroxaban.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2699MU2013 IN2013MU02699A (en) | 2013-08-19 | 2014-08-19 | |
US14/911,914 US9598403B2 (en) | 2013-08-19 | 2014-08-19 | Process for the preparation of rivaroxaban |
PCT/US2014/051583 WO2015026761A1 (en) | 2013-08-19 | 2014-08-19 | A process for the preparation of rivaroxaban |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2699MU2013 IN2013MU02699A (en) | 2013-08-19 | 2014-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2013MU02699A true IN2013MU02699A (en) | 2015-06-19 |
Family
ID=52484087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN2699MU2013 IN2013MU02699A (en) | 2013-08-19 | 2014-08-19 |
Country Status (3)
Country | Link |
---|---|
US (1) | US9598403B2 (en) |
IN (1) | IN2013MU02699A (en) |
WO (1) | WO2015026761A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110320306A (en) * | 2019-08-09 | 2019-10-11 | 南京科宁检测科技有限公司 | The method of derivatization HPLC-DAD measurement razaxaban gene poison impurity |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19962924A1 (en) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituted oxazolidinones and their use |
DE10300111A1 (en) | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Process for the preparation of 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4-morpholinyl) phenyl] -1,3-oxazolidin-5-yl} methyl ) -2-thiophenecarboxamide |
US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof |
CA2815063C (en) | 2010-10-18 | 2016-11-22 | Apotex Pharmachem Inc. | Processes for the preparation of rivaroxaban and intermediates thereof |
WO2013046211A1 (en) * | 2011-09-27 | 2013-04-04 | Symed Labs Limited | Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof |
-
2014
- 2014-08-19 US US14/911,914 patent/US9598403B2/en not_active Expired - Fee Related
- 2014-08-19 WO PCT/US2014/051583 patent/WO2015026761A1/en active Application Filing
- 2014-08-19 IN IN2699MU2013 patent/IN2013MU02699A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2015026761A1 (en) | 2015-02-26 |
US20160194309A1 (en) | 2016-07-07 |
US9598403B2 (en) | 2017-03-21 |
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