IN2013MU02370A - - Google Patents

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Publication number
IN2013MU02370A
IN2013MU02370A IN2370MU2013A IN2013MU02370A IN 2013MU02370 A IN2013MU02370 A IN 2013MU02370A IN 2370MU2013 A IN2370MU2013 A IN 2370MU2013A IN 2013MU02370 A IN2013MU02370 A IN 2013MU02370A
Authority
IN
India
Prior art keywords
present
inflammation
prevention
formula
pharmaceutical composition
Prior art date
Application number
Inventor
Rajiv Indravadan Modi
Chandan Hardhan Singh
Niravkumar Sureshbhai Sagar
Sunilkumar Ramsuratbhai Tivari
Bipin Dhanajibhai Gadhiya
Original Assignee
Cadila Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Pharmaceuticals Ltd filed Critical Cadila Pharmaceuticals Ltd
Priority to US14/904,734 priority Critical patent/US9708258B2/en
Priority to AU2014291683A priority patent/AU2014291683B2/en
Priority to JP2016526736A priority patent/JP6293271B2/en
Priority to EP14759311.5A priority patent/EP3022177B1/en
Priority to IN2370MU2013 priority patent/IN2013MU02370A/en
Priority to CA2918277A priority patent/CA2918277C/en
Priority to EA201690236A priority patent/EA030692B1/en
Priority to PCT/IB2014/063031 priority patent/WO2015008202A1/en
Priority to ES14759311.5T priority patent/ES2671998T3/en
Publication of IN2013MU02370A publication Critical patent/IN2013MU02370A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

The present invention relates to novel stable indole-3-carbinol derivatives of Formula-I and its pharmaceutical composition and biological activity. The present invention includes compositions and methods for the treatment and prevention of conditions associated with Inflammation.
IN2370MU2013 2013-07-16 2014-07-11 IN2013MU02370A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
US14/904,734 US9708258B2 (en) 2013-07-16 2014-07-11 Indole 3-carbinol derivatives
AU2014291683A AU2014291683B2 (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives
JP2016526736A JP6293271B2 (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives
EP14759311.5A EP3022177B1 (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives
IN2370MU2013 IN2013MU02370A (en) 2013-07-16 2014-07-11
CA2918277A CA2918277C (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives
EA201690236A EA030692B1 (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives
PCT/IB2014/063031 WO2015008202A1 (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives
ES14759311.5T ES2671998T3 (en) 2013-07-16 2014-07-11 Indole-3-carbinol derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2370MU2013 IN2013MU02370A (en) 2013-07-16 2014-07-11

Publications (1)

Publication Number Publication Date
IN2013MU02370A true IN2013MU02370A (en) 2015-06-19

Family

ID=52345790

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2370MU2013 IN2013MU02370A (en) 2013-07-16 2014-07-11

Country Status (9)

Country Link
US (1) US9708258B2 (en)
EP (1) EP3022177B1 (en)
JP (1) JP6293271B2 (en)
AU (1) AU2014291683B2 (en)
CA (1) CA2918277C (en)
EA (1) EA030692B1 (en)
ES (1) ES2671998T3 (en)
IN (1) IN2013MU02370A (en)
WO (1) WO2015008202A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906086A (en) * 2015-06-24 2015-09-16 安徽四正医药科技有限公司 Application of indole-3-methaol, bis(indoly)methane and derivatives thereof in medicine for treating glomerulonephritis
CN113260363A (en) * 2018-09-27 2021-08-13 阿瑞斯医疗有限公司 Graplacant (GRAPIPRANT) unit dosage form

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002060382A (en) * 2000-08-22 2002-02-26 Ajinomoto Co Inc Stereoisomer of monatin and use thereof, method for producing monatins and intermediate therefor
GB0614068D0 (en) * 2006-07-14 2006-08-23 Glaxo Group Ltd Compounds
US7807705B2 (en) * 2007-05-18 2010-10-05 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents

Also Published As

Publication number Publication date
EA201690236A1 (en) 2016-07-29
EP3022177A1 (en) 2016-05-25
ES2671998T3 (en) 2018-06-12
CA2918277C (en) 2021-02-16
EA030692B1 (en) 2018-09-28
AU2014291683A1 (en) 2016-02-18
US9708258B2 (en) 2017-07-18
AU2014291683B2 (en) 2017-11-02
JP6293271B2 (en) 2018-03-14
EP3022177B1 (en) 2018-03-28
JP2016527226A (en) 2016-09-08
CA2918277A1 (en) 2015-01-22
US20160159740A1 (en) 2016-06-09
WO2015008202A1 (en) 2015-01-22

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