IN2013MU02145A - - Google Patents

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Publication number
IN2013MU02145A
IN2013MU02145A IN2145MU2013A IN2013MU02145A IN 2013MU02145 A IN2013MU02145 A IN 2013MU02145A IN 2145MU2013 A IN2145MU2013 A IN 2145MU2013A IN 2013MU02145 A IN2013MU02145 A IN 2013MU02145A
Authority
IN
India
Prior art keywords
monoclonal antibody
purification
provides
desired monoclonal
purity
Prior art date
Application number
Inventor
Sanjay Bandyopadhyay
Sanjeev Kumar Mendiratta
Avanish Kumar Singh
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51655799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2013MU02145(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to ARP140102380A priority Critical patent/AR096713A1/en
Priority to TW103121726A priority patent/TWI596107B/en
Priority to EA201592192A priority patent/EA201592192A1/en
Priority to CA2911874A priority patent/CA2911874A1/en
Priority to JP2015563045A priority patent/JP6039828B2/en
Priority to US14/895,432 priority patent/US9708365B2/en
Priority to KR1020157035759A priority patent/KR101683415B1/en
Priority to PCT/IN2014/000421 priority patent/WO2014207763A1/en
Priority to IN2145MU2013 priority patent/IN2013MU02145A/en
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Priority to CN201480031532.XA priority patent/CN105263947A/en
Priority to MX2015016586A priority patent/MX350610B/en
Priority to NZ714079A priority patent/NZ714079A/en
Priority to BR112015031196A priority patent/BR112015031196A2/en
Priority to EP14777867.4A priority patent/EP3013849B1/en
Priority to AU2014300486A priority patent/AU2014300486B2/en
Priority to SG11201509502XA priority patent/SG11201509502XA/en
Publication of IN2013MU02145A publication Critical patent/IN2013MU02145A/en
Priority to ZA2015/08258A priority patent/ZA201508258B/en
Priority to IL242649A priority patent/IL242649A/en
Priority to HK16105366.7A priority patent/HK1217344A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)

Abstract

The present invention provides an improved method for the purification of monoclonal antibody from cell culture. Process of purification of the desired monoclonal antibody comprises affinity, hydrophobic interaction and optionally ion exchange column chromatography. It provides more than 99% purity of the desired monoclonal antibody.
IN2145MU2013 2013-06-25 2014-06-25 IN2013MU02145A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
ARP140102380A AR096713A1 (en) 2013-06-25 2014-06-24 PURIFICATION PROCESS FOR MONOCLONAL ANTIBODIES
TW103121726A TWI596107B (en) 2013-06-25 2014-06-24 Novel purification process for monoclonal antibodies
SG11201509502XA SG11201509502XA (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
MX2015016586A MX350610B (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies.
JP2015563045A JP6039828B2 (en) 2013-06-25 2014-06-25 Method for purifying monoclonal antibodies
US14/895,432 US9708365B2 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
KR1020157035759A KR101683415B1 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
PCT/IN2014/000421 WO2014207763A1 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
IN2145MU2013 IN2013MU02145A (en) 2013-06-25 2014-06-25
EA201592192A EA201592192A1 (en) 2013-06-25 2014-06-25 METHOD OF CLEANING MONOCLONAL ANTIBODIES
CN201480031532.XA CN105263947A (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
CA2911874A CA2911874A1 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
NZ714079A NZ714079A (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
BR112015031196A BR112015031196A2 (en) 2013-06-25 2014-06-25 “Monoclonal antibody purification process”
EP14777867.4A EP3013849B1 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
AU2014300486A AU2014300486B2 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies
ZA2015/08258A ZA201508258B (en) 2013-06-25 2015-11-09 Purification process for monoclonal antibodies
IL242649A IL242649A (en) 2013-06-25 2015-11-18 Purification process for monoclonal antibodies
HK16105366.7A HK1217344A1 (en) 2013-06-25 2016-05-11 Purification process for monoclonal antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2145MU2013 IN2013MU02145A (en) 2013-06-25 2014-06-25

Publications (1)

Publication Number Publication Date
IN2013MU02145A true IN2013MU02145A (en) 2015-06-05

Family

ID=51655799

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2145MU2013 IN2013MU02145A (en) 2013-06-25 2014-06-25

Country Status (19)

Country Link
US (1) US9708365B2 (en)
EP (1) EP3013849B1 (en)
JP (1) JP6039828B2 (en)
KR (1) KR101683415B1 (en)
CN (1) CN105263947A (en)
AR (1) AR096713A1 (en)
AU (1) AU2014300486B2 (en)
BR (1) BR112015031196A2 (en)
CA (1) CA2911874A1 (en)
EA (1) EA201592192A1 (en)
HK (1) HK1217344A1 (en)
IL (1) IL242649A (en)
IN (1) IN2013MU02145A (en)
MX (1) MX350610B (en)
NZ (1) NZ714079A (en)
SG (1) SG11201509502XA (en)
TW (1) TWI596107B (en)
WO (1) WO2014207763A1 (en)
ZA (1) ZA201508258B (en)

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Also Published As

Publication number Publication date
TWI596107B (en) 2017-08-21
KR20160003311A (en) 2016-01-08
NZ714079A (en) 2017-05-26
JP6039828B2 (en) 2016-12-07
JP2016525500A (en) 2016-08-25
WO2014207763A1 (en) 2014-12-31
SG11201509502XA (en) 2015-12-30
KR101683415B1 (en) 2016-12-06
AR096713A1 (en) 2016-01-27
AU2014300486A1 (en) 2015-11-26
ZA201508258B (en) 2017-03-29
BR112015031196A2 (en) 2017-07-25
US20160115195A1 (en) 2016-04-28
EA201592192A1 (en) 2016-07-29
CA2911874A1 (en) 2014-12-31
CN105263947A (en) 2016-01-20
AU2014300486B2 (en) 2016-06-30
EP3013849A1 (en) 2016-05-04
US9708365B2 (en) 2017-07-18
MX2015016586A (en) 2016-03-16
IL242649A (en) 2016-03-31
EP3013849B1 (en) 2017-09-13
TW201512217A (en) 2015-04-01
MX350610B (en) 2017-09-11
HK1217344A1 (en) 2017-01-06

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