IN2013DE03047A - - Google Patents
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- Publication number
- IN2013DE03047A IN2013DE03047A IN3047DE2013A IN2013DE03047A IN 2013DE03047 A IN2013DE03047 A IN 2013DE03047A IN 3047DE2013 A IN3047DE2013 A IN 3047DE2013A IN 2013DE03047 A IN2013DE03047 A IN 2013DE03047A
- Authority
- IN
- India
- Prior art keywords
- polysaccharide
- present
- protein
- relates
- group
- Prior art date
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The present invention relates to polysaccharide – protein conjugates with enhanced immunogenicity displaying significantly high antibody titres. The carrier protein is obtained from group of gram positive bacteria, polysaccharide fragment is obtained from group of gram negative bacteria, preferably from Haemophilus influenzae serotype b (Hib), Neisseria meningitidis serogroup A and C (MenA and MenC). The present invention also relates to a rapid and high yielding process of preparing the polysaccharide–protein conjugates in which derivatized carrier protein reacts with cleaved and depolymerized polysaccharide fragments of optimum length to obtain polysaccharide – protein conjugate employing reductive amination chemistry. The present invention further relates to a chemical process of polysaccharide fragmentation to optimum length for use in conjugation.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MYPI2016701265A MY194920A (en) | 2013-10-11 | 2014-10-10 | Polysaccharide ? protein conjugates with enhanced immunogenicity and rapid high yielding process thereof |
IN3047DE2013 IN2013DE03047A (en) | 2013-10-11 | 2014-10-10 | |
PCT/IB2014/065201 WO2015052684A2 (en) | 2013-10-11 | 2014-10-10 | Polysaccharide-protein conjugates with enhanced immunogenicity and rapid high yielding process thereof |
CN201480056001.6A CN105636608A (en) | 2013-10-11 | 2014-10-10 | Polysaccharide-protein conjugates with enhanced immunogenicity and rapid high yielding process thereof |
ZA2016/02375A ZA201602375B (en) | 2013-10-11 | 2016-04-08 | Polysaccharide-protein conjugates with enhanced immunogenicity and rapid high yielding process of preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3047DE2013 IN2013DE03047A (en) | 2013-10-11 | 2014-10-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2013DE03047A true IN2013DE03047A (en) | 2015-04-17 |
Family
ID=54397097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3047DE2013 IN2013DE03047A (en) | 2013-10-11 | 2014-10-10 |
Country Status (1)
Country | Link |
---|---|
IN (1) | IN2013DE03047A (en) |
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2014
- 2014-10-10 IN IN3047DE2013 patent/IN2013DE03047A/en unknown
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