IN2013CH05982AIN5982CH2013AIN2013CH05982AIN 2013CH05982 AIN2013CH05982 AIN 2013CH05982AIN 5982CH2013 AIN5982CH2013 AIN 5982CH2013AIN 2013CH05982 AIN2013CH05982 AIN 2013CH05982A
Authority
IN
India
Prior art keywords
etravirine
preparation
relates
present
purified
Prior art date
Application number
Inventor
Venkatavara Prasada Rao Korrapati Mr
Ravikanth Vysyaraju Mr
Sivakumaran Dr Meenakshisunderam
Original Assignee
Aurobindo Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurobindo Pharma LtdfiledCriticalAurobindo Pharma Ltd
Priority to IN5982CH2013priorityCriticalpatent/IN2013CH05982A/en
Publication of IN2013CH05982ApublicationCriticalpatent/IN2013CH05982A/en
The present invention relates to an improved process for the preparation of Etravirine (I) and its intermediates, wherein Des-bromo Etravirine (XI) is purified and this purified form as such used in the next step for the preparation of Etravirine (I). The present invention also relates to purification of Etravirine (I) from an aqueous solvent.
METHOD FOR TREATMENT OF INFLAMMATORY CONDITIONS USING S-[4-(3-FLUORO-3-METHYLBUTYRYLOXY)BUT-2-YNYL]-6α,9α-DIFLUORO-17α-(FURAN-2-YL)CARBONYLOXY-11β-HYDROXY-16α-METHYL-3-OXOANDROSTA-1,4-DIENE-17β-CARBOTHIOATE