IN2013CH04511A - - Google Patents

Info

Publication number
IN2013CH04511A
IN2013CH04511A IN4511CH2013A IN2013CH04511A IN 2013CH04511 A IN2013CH04511 A IN 2013CH04511A IN 4511CH2013 A IN4511CH2013 A IN 4511CH2013A IN 2013CH04511 A IN2013CH04511 A IN 2013CH04511A
Authority
IN
India
Prior art keywords
preparation
present
provides
ragorafenib
crystalline solid
Prior art date
Application number
Other languages
English (en)
Inventor
Reddy Bandi Parthasaradhi
Reddy Kura Rathnakar
Reddy Dasari Muralidhara
Rao Thungathurthy Srinivasa
Krishna Bandi Vamsi
Original Assignee
Hetero Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Research Foundation filed Critical Hetero Research Foundation
Priority to US15/026,694 priority Critical patent/US9518020B2/en
Priority to IN4511CH2013 priority patent/IN2013CH04511A/en
Priority to PCT/IN2014/000630 priority patent/WO2015049698A2/en
Publication of IN2013CH04511A publication Critical patent/IN2013CH04511A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IN4511CH2013 2013-10-04 2014-09-29 IN2013CH04511A (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US15/026,694 US9518020B2 (en) 2013-10-04 2014-09-29 Process for Regorafenib
IN4511CH2013 IN2013CH04511A (zh) 2013-10-04 2014-09-29
PCT/IN2014/000630 WO2015049698A2 (en) 2013-10-04 2014-09-29 Process for regorafenib

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN4511CH2013 IN2013CH04511A (zh) 2013-10-04 2014-09-29

Publications (1)

Publication Number Publication Date
IN2013CH04511A true IN2013CH04511A (zh) 2015-04-10

Family

ID=52779244

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4511CH2013 IN2013CH04511A (zh) 2013-10-04 2014-09-29

Country Status (3)

Country Link
US (1) US9518020B2 (zh)
IN (1) IN2013CH04511A (zh)
WO (1) WO2015049698A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105330600B (zh) * 2015-11-30 2018-05-22 山东罗欣药业集团股份有限公司 一种瑞戈菲尼的制备方法
CA3011662A1 (en) * 2016-01-18 2017-07-27 Natco Pharma Ltd An improved process for the preparation of regorafenib
CN108440403A (zh) * 2018-03-31 2018-08-24 山东罗欣药业集团恒欣药业有限公司 一种瑞戈非尼的制备方法
CN108558747A (zh) * 2018-03-31 2018-09-21 山东罗欣药业集团恒欣药业有限公司 一种瑞戈非尼的制备方法
CN114315710B (zh) * 2022-01-07 2024-04-26 江苏豪森药业集团有限公司 一种制备或纯化瑞戈非尼的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY191349A (en) * 2004-08-27 2022-06-17 Bayer Pharmaceuticals Corp New pharmaceutical compositions for the treatment of hyper-proliferative disorders
US20120225057A1 (en) * 2006-10-11 2012-09-06 Deciphera Pharmaceuticals, Llc Methods and compositions for the treatment of myeloproliferative diseases and other proliferative diseases
AR062927A1 (es) * 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
WO2011080749A1 (en) * 2009-12-29 2011-07-07 Hetero Research Foundation Process for purification of ziprasidone
AR081060A1 (es) * 2010-04-15 2012-06-06 Bayer Schering Pharma Ag Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida

Also Published As

Publication number Publication date
US20160251313A1 (en) 2016-09-01
US9518020B2 (en) 2016-12-13
WO2015049698A2 (en) 2015-04-09
WO2015049698A3 (en) 2015-08-13

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