IN2013CH04023A - - Google Patents

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Publication number
IN2013CH04023A
IN2013CH04023A IN4023CH2013A IN2013CH04023A IN 2013CH04023 A IN2013CH04023 A IN 2013CH04023A IN 4023CH2013 A IN4023CH2013 A IN 4023CH2013A IN 2013CH04023 A IN2013CH04023 A IN 2013CH04023A
Authority
IN
India
Prior art keywords
ticagrelor
preparation
relates
present
ecofriendly
Prior art date
Application number
Inventor
Velayudhan Nair Subha
Ravindra Babu Bollu
Kumar Dalasingh Prasanta
Sunil Kumar Indukuri Venkata
Ramanjaneyulu Gorantla Seeta
Original Assignee
Laurus Labs Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laurus Labs Pvt Ltd filed Critical Laurus Labs Pvt Ltd
Priority to IN4023CH2013 priority Critical patent/IN2013CH04023A/en
Priority to PCT/IN2014/000587 priority patent/WO2015037016A2/en
Publication of IN2013CH04023A publication Critical patent/IN2013CH04023A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Ceramic Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ABSTRACT: The present invention relates to an improved process for the preparation of ticagrelor, which involves ecofriendly reaction solvent and bases. The present invention also relates to a process for preparation of ticagrelor in crystalline Form or an amorphous form.
IN4023CH2013 2013-09-10 2014-09-10 IN2013CH04023A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN4023CH2013 IN2013CH04023A (en) 2013-09-10 2014-09-10
PCT/IN2014/000587 WO2015037016A2 (en) 2013-09-10 2014-09-10 An improved process for the preparation of ticagrelor and intermediates thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN4023CH2013 IN2013CH04023A (en) 2013-09-10 2014-09-10

Publications (1)

Publication Number Publication Date
IN2013CH04023A true IN2013CH04023A (en) 2015-08-07

Family

ID=52666472

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4023CH2013 IN2013CH04023A (en) 2013-09-10 2014-09-10

Country Status (2)

Country Link
IN (1) IN2013CH04023A (en)
WO (1) WO2015037016A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015162630A1 (en) 2014-04-25 2015-10-29 Anlon Chemical Research Organization Novel processes for preparing triazolo [4,5-d]- pyrimidines, including ticagrelor, vianew intermediates and new route of synthesis.
WO2016116942A1 (en) 2015-01-20 2016-07-28 Anlon Chemical Research Organization Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin
CN106243108A (en) * 2015-06-03 2016-12-21 四川海思科制药有限公司 A kind of highly purified ticagrelor and preparation method thereof
KR101787449B1 (en) 2016-07-29 2017-10-18 주식회사 종근당 Novel salts of Ticagrelor and Preparation Method thereof
CN106478636B (en) * 2016-08-30 2019-02-15 山东罗欣药业集团恒欣药业有限公司 Ticagrelor crystal form and preparation method
WO2020021110A1 (en) 2018-07-27 2020-01-30 Krka, D.D., Novo Mesto Pharmaceutical composition of ticagrelor
CN110437237A (en) * 2019-09-06 2019-11-12 上海汇伦生命科技有限公司 A kind of preparation method of the single crystallization of 1,2- diol compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0013407D0 (en) * 2000-06-02 2000-07-26 Astrazeneca Ab Forms of a chemical compound
SG196805A1 (en) * 2008-09-09 2014-02-13 Astrazeneca Ab A process for preparing [1s- [1-alpha, 2-alpha, 3-beta (1s*, 2r*) 5-beta] ] -3- [7- [2- (3, 4-dif luorophenyl) -cyclopropylamino] - 5- (propylthio) -3h-1, 2, 3-triazolo [4, 5-d] pyrimidin-3-yl] -5- (2- hydroxyethoxy) cyclopentane-1, 2-diol and to its intermediates
WO2012138981A2 (en) * 2011-04-06 2012-10-11 Teva Pharmaceutical Industries Ltd. New intermediates and processes for preparing ticagrelor

Also Published As

Publication number Publication date
WO2015037016A2 (en) 2015-03-19
WO2015037016A3 (en) 2015-06-04

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