IN2013CH00931AIN931CH2013AIN2013CH00931AIN 2013CH00931 AIN2013CH00931 AIN 2013CH00931AIN 931CH2013 AIN931CH2013 AIN 931CH2013AIN 2013CH00931 AIN2013CH00931 AIN 2013CH00931A
Authority
IN
India
Prior art keywords
butylsulfonylamino
butyloxy
piperidin
abstract
phenyl
Prior art date
Application number
Inventor
Sridevi Dr Surapanini
Nadamuni Dr Gollagunta
Aravinda Chava
Arun Kumar Potturi
Ramarao Pilla
Chandrasekhar Gandeti
Original Assignee
Gland Pharma Ltd
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Publication date
Application filed by Gland Pharma LtdfiledCriticalGland Pharma Ltd
Priority to IN931CH2013priorityCriticalpatent/IN2013CH00931A/en
Publication of IN2013CH00931ApublicationCriticalpatent/IN2013CH00931A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Medicinal Preparation
(AREA)
Abstract
Abstract A stable composition comprising 2-S-(n-Butylsulfonylamino)-3-[4-(4-(piperidin-4-yl)butyloxy)phenyl]propionic acid monohydrochloride monohydrate (Tirofiban hydrochloride) as active pharmaceutical ingredient and method for the preparation is disclosed. The composition exhibits an improved chromatographic profile and greater stability with respect to the particulate matter.
C6-c18-acylated derivative of hyaluronic acid, method of preparation thereof, nanomicellar composition on its basis, method of preparation thereof and method of preparation stabilized nanomicellar composition, and use thereof