IN2012DN06562A - - Google Patents
Info
- Publication number
- IN2012DN06562A IN2012DN06562A IN6562DEN2012A IN2012DN06562A IN 2012DN06562 A IN2012DN06562 A IN 2012DN06562A IN 6562DEN2012 A IN6562DEN2012 A IN 6562DEN2012A IN 2012DN06562 A IN2012DN06562 A IN 2012DN06562A
- Authority
- IN
- India
- Prior art keywords
- synthesis
- compounds
- general formula
- provides
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/23—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention provides an alternative synthesis of N-substituted aminotetralines which synthesis comprises catalytic asymmetric hydrogenation of compounds of general formula (A).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30174110P | 2010-02-05 | 2010-02-05 | |
PCT/EP2011/051549 WO2011095539A2 (en) | 2010-02-05 | 2011-02-03 | Novel process for the preparation of nitrogen substituted aminotetralins derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN06562A true IN2012DN06562A (en) | 2015-10-23 |
Family
ID=44118859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN6562DEN2012 IN2012DN06562A (en) | 2010-02-05 | 2011-02-03 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8729306B2 (en) |
EP (1) | EP2531486B1 (en) |
IN (1) | IN2012DN06562A (en) |
WO (1) | WO2011095539A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109580792A (en) * | 2017-09-28 | 2019-04-05 | 安徽省庆云医药股份有限公司 | A kind of method of liquid chromatography for separating and determining rotigotine and its optical isomer |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999018065A1 (en) | 1997-10-03 | 1999-04-15 | Chirotech Technology Limited | Chiral amines |
CN1185225C (en) | 1999-11-23 | 2005-01-19 | 阿德里斯制药公司 | Improved process for preparing nitrogen-substituted aminotetralins |
CA2307390C (en) | 2000-05-01 | 2005-06-28 | Torcan Chemical Ltd. | Enzymatic resolution of aminotetralins |
DE60100595T2 (en) | 2001-05-08 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Improved transdermal therapeutic system for the treatment of Parkinson's disease |
DE10220230A1 (en) | 2002-05-06 | 2003-11-27 | Sanol Arznei Schwarz Gmbh | Use of Rotigotine to treat restless leg syndrome |
DE10334188B4 (en) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Use of rotigotine to treat depression |
DE10361259A1 (en) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Use of Rotigotine in Early Stage Parkinson's Disease to Prevent Further Neuronal Loss |
DE102004014841B4 (en) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Use of rotigotine for the treatment and prevention of Parkinson-Plus syndrome |
-
2011
- 2011-02-03 EP EP11702630.2A patent/EP2531486B1/en active Active
- 2011-02-03 US US13/576,289 patent/US8729306B2/en not_active Expired - Fee Related
- 2011-02-03 IN IN6562DEN2012 patent/IN2012DN06562A/en unknown
- 2011-02-03 WO PCT/EP2011/051549 patent/WO2011095539A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2011095539A2 (en) | 2011-08-11 |
EP2531486B1 (en) | 2017-06-21 |
EP2531486A2 (en) | 2012-12-12 |
WO2011095539A3 (en) | 2011-11-17 |
US8729306B2 (en) | 2014-05-20 |
US20120302790A1 (en) | 2012-11-29 |
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