IN2012DN04915A - - Google Patents
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- Publication number
- IN2012DN04915A IN2012DN04915A IN4915DEN2012A IN2012DN04915A IN 2012DN04915 A IN2012DN04915 A IN 2012DN04915A IN 4915DEN2012 A IN4915DEN2012 A IN 4915DEN2012A IN 2012DN04915 A IN2012DN04915 A IN 2012DN04915A
- Authority
- IN
- India
- Prior art keywords
- c6alkyl
- ch2c3
- c4alkoxy
- c4alkyl
- carbocyclyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Abstract
Compounds of the formula (I) wherein R1a is H; and R1b is C1-C6alkyl, Carbocyclyl or Het; or R1a and R1b together define a saturated cyclic amine with 3-6 ring atoms; R2a and R2b are independently H, halo, C1-C4alkyl, C1-C4haloalkyl or C1-C4alkoxy, or R2a and R2b together with the carbon atom to which they are attached form a C3-C6cycloalkyl; R3 is a branched C5-C10 alkyl chain, C2-C4haloalkyl or -CH2C3-C7 cycloalkyl; R4 is C1-C6alkyl, C1-C6haloalkyl, C1-C6alkylamino or C1-C6dialkylamino; for use in the prophylaxis or treatment of a disorder characterised by inappropriate expression or activation of cathepsin S.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0950951 | 2009-12-10 | ||
GBGB1010084.0A GB201010084D0 (en) | 2010-06-16 | 2010-06-16 | Cysteine protease inhibitors |
PCT/IB2010/055738 WO2011070541A1 (en) | 2009-12-10 | 2010-12-10 | Cysteine protease inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN04915A true IN2012DN04915A (en) | 2015-09-25 |
Family
ID=44145161
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN4915DEN2012 IN2012DN04915A (en) | 2009-12-10 | 2010-12-10 | |
IN4914DEN2012 IN2012DN04914A (en) | 2009-12-10 | 2010-12-10 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN4914DEN2012 IN2012DN04914A (en) | 2009-12-10 | 2010-12-10 |
Country Status (13)
Country | Link |
---|---|
US (2) | US8859605B2 (en) |
EP (2) | EP2509956B1 (en) |
JP (2) | JP2013513598A (en) |
KR (2) | KR20120110173A (en) |
CN (2) | CN102834383A (en) |
AU (1) | AU2010329468B2 (en) |
BR (2) | BR112012014091A2 (en) |
CA (2) | CA2782294A1 (en) |
EA (1) | EA201200866A1 (en) |
IN (2) | IN2012DN04915A (en) |
MX (2) | MX2012006653A (en) |
RU (1) | RU2012128859A (en) |
WO (2) | WO2011070541A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2744888A1 (en) * | 2008-12-19 | 2010-06-24 | Medivir Uk Ltd | Cysteine protease inhibitors |
CA2782294A1 (en) * | 2009-12-10 | 2011-06-16 | Medivir Uk Limited | Cysteine protease inhibitors |
EP2582660B1 (en) * | 2010-06-16 | 2015-07-22 | Medivir UK Ltd | New cathepsin s protease inhibitors, useful in the treatment of e.g. autoimmune disorders, allergy and chronic pain conditions |
WO2012168852A1 (en) * | 2011-06-08 | 2012-12-13 | Medivir Uk Ltd | Cysteine protease inhibitors |
WO2012172473A1 (en) * | 2011-06-13 | 2012-12-20 | Medivir Uk Ltd | Cysteine protease inhibitors |
GB201314503D0 (en) * | 2013-08-13 | 2013-09-25 | Medivir Ab | Cysteine protease inhibitor salt |
CN113332420B (en) * | 2021-06-30 | 2023-07-28 | 蚌埠医学院 | Application of schistosoma japonica cysteine protease inhibitor in atherosclerosis |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0564561A4 (en) * | 1990-12-28 | 1994-08-10 | Georgia Tech Res Inst | Peptides ketoamides, ketoacids, and ketoesters |
JP3892187B2 (en) * | 1998-11-12 | 2007-03-14 | 生化学工業株式会社 | Cyclic amide derivative |
NZ528944A (en) * | 2001-06-01 | 2007-09-28 | Axys Pharm Inc | Chemical compounds and pharmaceutical compositions as cathepsin S inhibitors |
MXPA04002282A (en) * | 2001-09-14 | 2005-03-07 | Axis Pharmaceutical Inc | Novel compounds and compositions as cathepsin inhibitors. |
ES2399362T3 (en) * | 2002-04-25 | 2013-03-27 | Ono Pharmaceutical Co., Ltd. | Compounds derived from diketohydrazine and drugs containing the compounds as active ingredient |
EA017874B1 (en) * | 2005-03-21 | 2013-03-29 | Вайробей, Инк. | Alpha ketoamide compounds as cysteine protease inhibitors |
JP2008533205A (en) | 2005-03-21 | 2008-08-21 | セレーラ ジェノミックス | Α-Ketoamide compounds as cysteine protease inhibitors |
ZA200708602B (en) * | 2005-03-21 | 2009-02-25 | Applera Corp | Alpha ketoamide compounds as cysteine protease inhibitors |
CA2744888A1 (en) * | 2008-12-19 | 2010-06-24 | Medivir Uk Ltd | Cysteine protease inhibitors |
CA2782294A1 (en) * | 2009-12-10 | 2011-06-16 | Medivir Uk Limited | Cysteine protease inhibitors |
-
2010
- 2010-12-10 CA CA2782294A patent/CA2782294A1/en not_active Abandoned
- 2010-12-10 AU AU2010329468A patent/AU2010329468B2/en not_active Ceased
- 2010-12-10 BR BR112012014091A patent/BR112012014091A2/en not_active IP Right Cessation
- 2010-12-10 US US13/514,760 patent/US8859605B2/en not_active Expired - Fee Related
- 2010-12-10 CN CN2010800635616A patent/CN102834383A/en active Pending
- 2010-12-10 CA CA2782292A patent/CA2782292A1/en not_active Abandoned
- 2010-12-10 KR KR1020127017803A patent/KR20120110173A/en not_active Application Discontinuation
- 2010-12-10 WO PCT/IB2010/055738 patent/WO2011070541A1/en active Application Filing
- 2010-12-10 JP JP2012542677A patent/JP2013513598A/en active Pending
- 2010-12-10 EA EA201200866A patent/EA201200866A1/en unknown
- 2010-12-10 BR BR112012013861A patent/BR112012013861A2/en not_active IP Right Cessation
- 2010-12-10 WO PCT/IB2010/055732 patent/WO2011070539A1/en active Application Filing
- 2010-12-10 KR KR1020127017796A patent/KR20120093423A/en not_active Application Discontinuation
- 2010-12-10 MX MX2012006653A patent/MX2012006653A/en not_active Application Discontinuation
- 2010-12-10 RU RU2012128859/04A patent/RU2012128859A/en unknown
- 2010-12-10 EP EP10835593.4A patent/EP2509956B1/en active Active
- 2010-12-10 IN IN4915DEN2012 patent/IN2012DN04915A/en unknown
- 2010-12-10 US US13/514,758 patent/US8815809B2/en not_active Expired - Fee Related
- 2010-12-10 EP EP10835594.2A patent/EP2509957A4/en not_active Withdrawn
- 2010-12-10 IN IN4914DEN2012 patent/IN2012DN04914A/en unknown
- 2010-12-10 CN CN2010800635673A patent/CN102858751A/en active Pending
- 2010-12-10 JP JP2012542676A patent/JP2013513597A/en active Pending
- 2010-12-10 MX MX2012006652A patent/MX2012006652A/en unknown
Also Published As
Publication number | Publication date |
---|---|
RU2012128859A (en) | 2014-01-20 |
CA2782294A1 (en) | 2011-06-16 |
AU2010329468A1 (en) | 2012-06-14 |
JP2013513598A (en) | 2013-04-22 |
JP2013513597A (en) | 2013-04-22 |
BR112012013861A2 (en) | 2017-09-26 |
US8859605B2 (en) | 2014-10-14 |
EP2509956A1 (en) | 2012-10-17 |
KR20120093423A (en) | 2012-08-22 |
EA201200866A1 (en) | 2012-12-28 |
US8815809B2 (en) | 2014-08-26 |
CA2782292A1 (en) | 2011-06-16 |
AU2010329468B2 (en) | 2013-08-22 |
EP2509956A4 (en) | 2013-06-19 |
US20120283305A1 (en) | 2012-11-08 |
EP2509956B1 (en) | 2014-07-23 |
EP2509957A1 (en) | 2012-10-17 |
MX2012006652A (en) | 2012-11-30 |
AU2010329470A1 (en) | 2012-06-14 |
WO2011070541A1 (en) | 2011-06-16 |
MX2012006653A (en) | 2012-11-30 |
KR20120110173A (en) | 2012-10-09 |
CN102858751A (en) | 2013-01-02 |
EP2509957A4 (en) | 2013-05-22 |
AU2010329470B2 (en) | 2013-08-22 |
IN2012DN04914A (en) | 2015-09-25 |
WO2011070539A1 (en) | 2011-06-16 |
BR112012014091A2 (en) | 2017-04-04 |
US20120309673A1 (en) | 2012-12-06 |
CN102834383A (en) | 2012-12-19 |
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