IN2012DN04867A - - Google Patents

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Publication number
IN2012DN04867A
IN2012DN04867A IN4867DEN2012A IN2012DN04867A IN 2012DN04867 A IN2012DN04867 A IN 2012DN04867A IN 4867DEN2012 A IN4867DEN2012 A IN 4867DEN2012A IN 2012DN04867 A IN2012DN04867 A IN 2012DN04867A
Authority
IN
India
Prior art keywords
women
additional
benefits
compositions
antiovulatory
Prior art date
Application number
Inventor
Regine Sitruk-Ware
Dario Norberto Ramon Carrara
Arnaud Grenier
Original Assignee
Population Council Inc
Antares Pharma Ipl Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Population Council Inc, Antares Pharma Ipl Ag filed Critical Population Council Inc
Publication of IN2012DN04867A publication Critical patent/IN2012DN04867A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Abstract

The invention discloses compositions and methods for ensuring in both women of fertile age where it ensures also a contraception with additional health benefits and in postmenopausal women where it offers a hormonal therapy with additional medical benefits such as the potential for lower risk of thrombosis. The aforementioned compositions comprising NES as a potent progestational and antiovulatory agent with no androgenic nor estrogenic nor glucocorticoid effect, and combined with estradiol formulated for non-oral transdermal administration as specific daily doses.
IN4867DEN2012 2009-12-17 2010-12-17 IN2012DN04867A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28751409P 2009-12-17 2009-12-17
PCT/US2010/060941 WO2011084668A1 (en) 2009-12-17 2010-12-17 Nestorone®/estradiol transdermal gel

Publications (1)

Publication Number Publication Date
IN2012DN04867A true IN2012DN04867A (en) 2015-09-25

Family

ID=43640394

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4867DEN2012 IN2012DN04867A (en) 2009-12-17 2010-12-17

Country Status (14)

Country Link
US (1) US9682087B2 (en)
EP (1) EP2512486B1 (en)
JP (1) JP6082249B2 (en)
KR (2) KR20120107492A (en)
CN (1) CN102753180A (en)
AU (1) AU2010339867B2 (en)
BR (1) BR112012014059B1 (en)
CA (1) CA2782075C (en)
ES (1) ES2641613T3 (en)
IN (1) IN2012DN04867A (en)
MX (1) MX363536B (en)
NZ (1) NZ600907A (en)
WO (1) WO2011084668A1 (en)
ZA (1) ZA201204267B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6285866B2 (en) 2011-11-23 2018-02-28 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． Natural complex hormone replacement preparations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CN102657661A (en) * 2012-04-15 2012-09-12 温州医学院 Pharmaceutical application of Nestorone in preparing Alzheimer disease
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9433680B2 (en) 2013-01-31 2016-09-06 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9452173B2 (en) 2013-01-31 2016-09-27 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9446131B2 (en) 2013-01-31 2016-09-20 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US8778365B1 (en) 2013-01-31 2014-07-15 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
WO2016018993A1 (en) 2014-07-29 2016-02-04 Therapeuticsmd, Inc. Transdermal cream
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
RU2648470C2 (en) * 2016-03-03 2018-03-26 Государственное бюджетное образовательное учреждение высшего профессионального образования "Уральский государственный медицинский университет Министерства здравоохранения Российской Федерации" (ГБОУ ВПО УГМУ Минздрава России) Method of optimization of treatment of women by cardiotropic therapy and hormone replacement therapy for estrogendeficiency with hypertension in the late reproductive period
BR112018070199A2 (en) 2016-04-01 2019-01-29 Therapeuticsmd Inc pharmaceutical composition of steroid hormone
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
EP4313318A1 (en) * 2021-03-30 2024-02-07 Viatris Inc. Transdermal systems having low dose estrogen and methods of making and use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018570A1 (en) 1990-06-01 1991-12-12 Robertson, Dale, N. Therapeutically effective topical application of st1435
US5198223A (en) 1990-10-29 1993-03-30 Alza Corporation Transdermal formulations, methods and devices
US5122382A (en) 1990-10-29 1992-06-16 Alza Corporation Transdermal contraceptive formulations, methods and devices
JPH04342531A (en) 1991-05-21 1992-11-30 Sekisui Chem Co Ltd Percutaneous drug
US7198801B2 (en) * 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
BR112012009306A2 (en) 2009-10-19 2016-06-07 Population Coucil Inc method for myelin regeneration in a patient

Also Published As

Publication number Publication date
BR112012014059A2 (en) 2016-07-05
US20130045953A1 (en) 2013-02-21
EP2512486B1 (en) 2017-06-28
WO2011084668A1 (en) 2011-07-14
ES2641613T3 (en) 2017-11-10
JP6082249B2 (en) 2017-02-15
CA2782075A1 (en) 2011-07-14
EP2512486A1 (en) 2012-10-24
CN102753180A (en) 2012-10-24
NZ600907A (en) 2013-11-29
BR112012014059A8 (en) 2017-12-26
KR20120107492A (en) 2012-10-02
AU2010339867A1 (en) 2012-07-19
MX363536B (en) 2019-03-27
MX2012006755A (en) 2012-11-23
BR112012014059B1 (en) 2020-03-10
ZA201204267B (en) 2013-01-31
AU2010339867B2 (en) 2014-07-24
KR20180084149A (en) 2018-07-24
KR101928321B1 (en) 2018-12-12
JP2013514984A (en) 2013-05-02
CA2782075C (en) 2015-06-30
US9682087B2 (en) 2017-06-20

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