IN2012DN03023A - - Google Patents
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- Publication number
- IN2012DN03023A IN2012DN03023A IN3023DEN2012A IN2012DN03023A IN 2012DN03023 A IN2012DN03023 A IN 2012DN03023A IN 3023DEN2012 A IN3023DEN2012 A IN 3023DEN2012A IN 2012DN03023 A IN2012DN03023 A IN 2012DN03023A
- Authority
- IN
- India
- Prior art keywords
- salts
- treatment
- pharmaceutical compositions
- well
- cognitive impairment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Novel crystalline salts of 3-[l-(4-chlorophenyl)-trans-3-fluorocyclobutyl]-4,5-dicyclopropyl-r-4H-l,2,4-triazole are potent inhibitors of 11 ß-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53920604P | 2004-01-26 | 2004-01-26 | |
PCT/US2005/001928 WO2005073200A1 (en) | 2004-01-26 | 2005-01-21 | Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN03023A true IN2012DN03023A (en) | 2015-07-31 |
Family
ID=34826043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3023DEN2012 IN2012DN03023A (en) | 2004-01-26 | 2005-01-21 |
Country Status (8)
Country | Link |
---|---|
US (1) | US7875642B2 (en) |
EP (1) | EP1711477A4 (en) |
JP (1) | JP2007519726A (en) |
CN (1) | CN1910161A (en) |
AU (1) | AU2005207925B2 (en) |
CA (1) | CA2553345C (en) |
IN (1) | IN2012DN03023A (en) |
WO (1) | WO2005073200A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1866298A2 (en) | 2005-03-31 | 2007-12-19 | Takeda San Diego, Inc. | Hydroxysteroid dehydrogenase inhibitors |
US7579360B2 (en) | 2005-06-09 | 2009-08-25 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
US7572807B2 (en) | 2005-06-09 | 2009-08-11 | Bristol-Myers Squibb Company | Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors |
WO2007038452A1 (en) * | 2005-09-28 | 2007-04-05 | Merck & Co., Inc. | Process for synthesizing 1,2,4-triazoles |
BRPI0710479A2 (en) | 2006-01-18 | 2012-08-14 | Hoffmann La Roche | compound, process for its preparation, pharmaceutical composition, use of a compound and method of treating disease or metabolic disorder. |
TW200800898A (en) | 2006-02-07 | 2008-01-01 | Wyeth Corp | 11-Beta HSD1 inhibitors |
PE20110235A1 (en) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | PHARMACEUTICAL COMBINATIONS INCLUDING LINAGLIPTIN AND METMORPHINE |
US8119658B2 (en) | 2007-10-01 | 2012-02-21 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
WO2012041013A1 (en) * | 2010-10-01 | 2012-04-05 | Shan Dong Luye Pharmaceutical Co., Ltd. | Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1037880E (en) | 1997-12-11 | 2004-11-30 | Janssen Pharmaceutica Nv | MIMETIC ANILIDES OF RETINOIC ACID |
US6503935B1 (en) | 1998-08-07 | 2003-01-07 | Abbott Laboratories | Imidazoles and related compounds as α1A agonists |
US20030073850A1 (en) | 1998-08-07 | 2003-04-17 | Altenbach Robert J. | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use |
SE0001899D0 (en) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
WO2003004497A1 (en) | 2001-07-05 | 2003-01-16 | Sumitomo Pharmaceuticals Company, Limited | Novel heterocyclic compound |
CA2474168A1 (en) * | 2002-02-01 | 2003-08-14 | Merck & Co., Inc. | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia |
AR040241A1 (en) * | 2002-06-10 | 2005-03-23 | Merck & Co Inc | INHIBITORS OF 11-BETA-HYDROXIESTEROID DEHYDROGRENASE 1 FOR THE TREATMENT OF DIABETES OBESITY AND DISLIPIDEMIA |
-
2005
- 2005-01-21 JP JP2006551299A patent/JP2007519726A/en active Pending
- 2005-01-21 WO PCT/US2005/001928 patent/WO2005073200A1/en not_active Application Discontinuation
- 2005-01-21 US US10/587,110 patent/US7875642B2/en active Active
- 2005-01-21 IN IN3023DEN2012 patent/IN2012DN03023A/en unknown
- 2005-01-21 CN CNA2005800031244A patent/CN1910161A/en active Pending
- 2005-01-21 AU AU2005207925A patent/AU2005207925B2/en not_active Ceased
- 2005-01-21 CA CA2553345A patent/CA2553345C/en not_active Expired - Fee Related
- 2005-01-21 EP EP05711768A patent/EP1711477A4/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP1711477A1 (en) | 2006-10-18 |
WO2005073200A1 (en) | 2005-08-11 |
US20090186928A1 (en) | 2009-07-23 |
CN1910161A (en) | 2007-02-07 |
CA2553345C (en) | 2011-11-15 |
EP1711477A4 (en) | 2009-06-10 |
AU2005207925A1 (en) | 2005-08-11 |
JP2007519726A (en) | 2007-07-19 |
AU2005207925B2 (en) | 2008-09-04 |
CA2553345A1 (en) | 2005-08-11 |
US7875642B2 (en) | 2011-01-25 |
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