IN2012DN02433A - - Google Patents
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- Publication number
- IN2012DN02433A IN2012DN02433A IN2433DEN2012A IN2012DN02433A IN 2012DN02433 A IN2012DN02433 A IN 2012DN02433A IN 2433DEN2012 A IN2433DEN2012 A IN 2433DEN2012A IN 2012DN02433 A IN2012DN02433 A IN 2012DN02433A
- Authority
- IN
- India
- Prior art keywords
- present
- antalgics
- morphine
- involvement
- identifying
- Prior art date
Links
- 230000000146 antalgic effect Effects 0.000 abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- 102000004257 Potassium Channel Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 108020001213 potassium channel Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention relates to treating and preventing pain. More particularly the present invention demonstrates the involvement of K2P potassium channels in the antalgic effect of morphine. The present invention therefore provides a screening method for identifying antalgics.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0956477A FR2950362B1 (en) | 2009-09-21 | 2009-09-21 | USE OF K2P POTASSIUM CHANNEL ACTIVATORS AS ANALGIC. |
| PCT/FR2010/051968 WO2011033241A1 (en) | 2009-09-21 | 2010-09-21 | Use of k2p potassium channel activators as antalgics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02433A true IN2012DN02433A (en) | 2015-08-21 |
Family
ID=42115665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2433DEN2012 IN2012DN02433A (en) | 2009-09-21 | 2010-09-21 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9448242B2 (en) |
| EP (1) | EP2480893B1 (en) |
| CN (1) | CN102597780B (en) |
| CA (1) | CA2774861C (en) |
| DK (1) | DK2480893T3 (en) |
| ES (1) | ES2517925T3 (en) |
| FR (1) | FR2950362B1 (en) |
| IN (1) | IN2012DN02433A (en) |
| WO (1) | WO2011033241A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2797886A2 (en) * | 2011-12-30 | 2014-11-05 | Ecole Nationale Superieure de Chimie de Clermont Ferrand | Pain relief compounds |
| WO2024126778A1 (en) * | 2022-12-16 | 2024-06-20 | Centre National De La Recherche Scientifique | Process for reversibly inhibiting two-pore potassium channels and inducing nociception, with light spatiotemporal resolution |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1192126A (en) * | 1967-10-05 | 1970-05-20 | Centre Nat Rech Scient | Indole Derivatives and their production |
| FR2623498B1 (en) * | 1987-11-24 | 1990-04-06 | Bioprojet Soc Civ | NOVEL ENANTIOMERIC COMPOUNDS DERIVED FROM AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC APPLICATIONS |
| US20030165806A1 (en) * | 1997-03-11 | 2003-09-04 | Mark H. Pausch | Potassium channels, nucleotide sequences encoding them, and methods of using same |
| US5919473A (en) * | 1997-05-12 | 1999-07-06 | Elkhoury; George F. | Methods and devices for delivering opioid analgesics to wounds via a subdermal implant |
| US7112403B1 (en) * | 1998-09-01 | 2006-09-26 | Centre National De La Recherche Scientifique | Method for the identification of anesthetics |
| US7955616B2 (en) * | 2003-09-23 | 2011-06-07 | Orthocon, Inc. | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects |
| GB0329310D0 (en) * | 2003-12-18 | 2004-01-21 | Univ Keele | Method |
| EP2077126A1 (en) * | 2008-01-07 | 2009-07-08 | Graftys | Analgesic apatitic calcium-phosphate cement |
-
2009
- 2009-09-21 FR FR0956477A patent/FR2950362B1/en not_active Expired - Fee Related
-
2010
- 2010-09-21 US US13/497,353 patent/US9448242B2/en not_active Expired - Fee Related
- 2010-09-21 CA CA2774861A patent/CA2774861C/en active Active
- 2010-09-21 EP EP10771161.6A patent/EP2480893B1/en active Active
- 2010-09-21 ES ES10771161.6T patent/ES2517925T3/en active Active
- 2010-09-21 CN CN201080050386.7A patent/CN102597780B/en not_active Expired - Fee Related
- 2010-09-21 WO PCT/FR2010/051968 patent/WO2011033241A1/en active Application Filing
- 2010-09-21 IN IN2433DEN2012 patent/IN2012DN02433A/en unknown
- 2010-09-21 DK DK10771161.6T patent/DK2480893T3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2950362A1 (en) | 2011-03-25 |
| FR2950362B1 (en) | 2011-10-21 |
| US20120260354A1 (en) | 2012-10-11 |
| US9448242B2 (en) | 2016-09-20 |
| EP2480893B1 (en) | 2014-08-27 |
| CN102597780B (en) | 2014-11-12 |
| CN102597780A (en) | 2012-07-18 |
| EP2480893A1 (en) | 2012-08-01 |
| CA2774861A1 (en) | 2011-03-24 |
| CA2774861C (en) | 2017-08-08 |
| DK2480893T3 (en) | 2014-09-29 |
| WO2011033241A1 (en) | 2011-03-24 |
| ES2517925T3 (en) | 2014-11-04 |
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