IN2012DN02413A - - Google Patents
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- Publication number
- IN2012DN02413A IN2012DN02413A IN2413DEN2012A IN2012DN02413A IN 2012DN02413 A IN2012DN02413 A IN 2012DN02413A IN 2413DEN2012 A IN2413DEN2012 A IN 2413DEN2012A IN 2012DN02413 A IN2012DN02413 A IN 2012DN02413A
- Authority
- IN
- India
- Prior art keywords
- proteins
- engineered
- ecry1ba
- cry1ba
- disclosed
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 241000238631 Hexapoda Species 0.000 abstract 2
- 241000607479 Yersinia pestis Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000749 insecticidal effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pest Control & Pesticides (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Insects & Arthropods (AREA)
- Environmental Sciences (AREA)
- Physiology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Catching Or Destruction (AREA)
Abstract
Improved compositions and methods for controlling pests are disclosed. In particular, novel engineered Cry1Ba (eCry1Ba) proteins having improved toxicity to lepidopteran insect pests are provided. By substituting at least one amino acid in domain I of a Cry1Ba protein an engineered Cry1Ba protein having substantially altered insecticidal properties is designed. Further, a method of making the engineered Cry I Ba proteins and methods of using the ecry1Ba nucleic acid sequences, for example in transgenic plants to express eCry1B proteins to confer protection from insect damage are disclosed.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24798609P | 2009-10-02 | 2009-10-02 | |
| PCT/US2010/050369 WO2011041256A2 (en) | 2009-10-02 | 2010-09-27 | Insecticidal proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02413A true IN2012DN02413A (en) | 2015-08-21 |
Family
ID=43826844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2413DEN2012 IN2012DN02413A (en) | 2009-10-02 | 2010-09-27 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US9243262B2 (en) |
| EP (1) | EP2482639B1 (en) |
| CN (2) | CN102596988B (en) |
| AU (1) | AU2010300850B2 (en) |
| BR (1) | BR112012009381A2 (en) |
| CA (1) | CA2775582A1 (en) |
| CL (1) | CL2012000799A1 (en) |
| IL (1) | IL218798A0 (en) |
| IN (1) | IN2012DN02413A (en) |
| MX (1) | MX342640B (en) |
| PH (1) | PH12012500642A1 (en) |
| RU (1) | RU2613778C2 (en) |
| UA (1) | UA110925C2 (en) |
| WO (1) | WO2011041256A2 (en) |
| ZA (1) | ZA201202266B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA029891B1 (en) | 2008-12-16 | 2018-05-31 | Зингента Партисипейшнс Аг | CORN CHROMOSOME SITE-TARGET AND METHOD FOR OBTAINING A TRANSGENOUS CORN PLANT |
| IN2012DN02413A (en) | 2009-10-02 | 2015-08-21 | Syngenta Participations Ag | |
| CN103146717A (en) * | 2013-02-25 | 2013-06-12 | 北京大北农科技集团股份有限公司 | Insecticidal gene and use thereof |
| US20140242048A1 (en) * | 2013-02-25 | 2014-08-28 | Beijing Dabeinong Technology Group Co., Ltd. | Methods For Controlling Pests |
| EP3207144B1 (en) * | 2014-10-16 | 2019-05-01 | Monsanto Technology LLC | Lepidopteran-active cry1da1 amino acid sequence variant proteins |
| PE20170895A1 (en) * | 2014-10-16 | 2017-07-12 | Monsanto Technology Llc | NOVEDOUS INSECTICIDE CHEMERIC PROTEINS TOXIC OR INHIBITOR OF LEPIDOPTER PESTS |
| UA125168C2 (en) | 2014-10-16 | 2022-01-26 | Піонір Хай-Бред Інтернешнл, Інк. | A VARIANT Cry1B POLYPEPTIDE |
| US11130964B2 (en) | 2014-11-20 | 2021-09-28 | Monsanto Technology Llc | Insect inhibitory proteins |
| UA125336C2 (en) | 2015-06-22 | 2022-02-23 | Аґбайомі, Інк. | PESTICIDE GENE AND METHOD OF ITS APPLICATION |
| ES2892627T3 (en) * | 2015-08-27 | 2022-02-04 | Monsanto Technology Llc | Novel insect inhibitory proteins |
| CN108602862B (en) * | 2016-01-26 | 2022-09-02 | 先锋国际良种公司 | Novel bacillus thuringiensis gene with lepidopteran activity |
| WO2018111553A1 (en) * | 2016-12-12 | 2018-06-21 | Syngenta Participations Ag | Engineered pesticidal proteins and methods of controlling plant pests |
| CN109517069A (en) * | 2018-10-18 | 2019-03-26 | 先正达参股股份有限公司 | It is a kind of for expressing the efficient protein matter expression system of Bt insecticidal proteins |
| CN111676233A (en) * | 2020-06-17 | 2020-09-18 | 中国农业科学院作物科学研究所 | Anti-insect gene Cry1Ab-1 and its encoded protein and application |
| WO2025106342A1 (en) * | 2023-11-15 | 2025-05-22 | Syngenta Crop Protection Ag | Nucleic acid molecules for conferring insecticidal properties in plants |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| PT89915B (en) | 1988-03-08 | 1994-10-31 | Ciba Geigy Ag | PROCESS FOR THE PREPARATION OF CHEMICALLY ADJUSTABLE DNA SEQUENCES |
| US5614395A (en) | 1988-03-08 | 1997-03-25 | Ciba-Geigy Corporation | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof |
| NZ230375A (en) | 1988-09-09 | 1991-07-26 | Lubrizol Genetics Inc | Synthetic gene encoding b. thuringiensis insecticidal protein |
| JP3364616B2 (en) | 1989-02-24 | 2003-01-08 | モンサント テクノロジー エルエルシー | Synthetic plant genes and preparation methods |
| US6855873B1 (en) | 1989-05-31 | 2005-02-15 | Bayer Bioscience, N.V. | Recombinant plant expressing non-competitively binding Bt insecticidal cryatal proteins |
| EP0400246A1 (en) * | 1989-05-31 | 1990-12-05 | Plant Genetic Systems, N.V. | Prevention of Bt resistance development |
| US5187091A (en) * | 1990-03-20 | 1993-02-16 | Ecogen Inc. | Bacillus thuringiensis cryiiic gene encoding toxic to coleopteran insects |
| ES2187497T3 (en) | 1990-04-12 | 2003-06-16 | Syngenta Participations Ag | PROMOTERS PREFERREDLY IN FABRICS. |
| US5451513A (en) | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
| US5994629A (en) | 1991-08-28 | 1999-11-30 | Novartis Ag | Positive selection |
| GB9304200D0 (en) | 1993-03-02 | 1993-04-21 | Sandoz Ltd | Improvements in or relating to organic compounds |
| UA48104C2 (en) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect |
| EP0589110A1 (en) * | 1992-08-19 | 1994-03-30 | Plant Genetic Systems N.V. | Control of ostrinia |
| US5530197A (en) * | 1992-08-19 | 1996-06-25 | Plant Genetic Systems, N.V. | Control of ostrinia |
| US5849870A (en) | 1993-03-25 | 1998-12-15 | Novartis Finance Corporation | Pesticidal proteins and strains |
| US5877012A (en) | 1993-03-25 | 1999-03-02 | Novartis Finance Corporation | Class of proteins for the control of plant pests |
| GB9318207D0 (en) | 1993-09-02 | 1993-10-20 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5576198A (en) | 1993-12-14 | 1996-11-19 | Calgene, Inc. | Controlled expression of transgenic constructs in plant plastids |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5545817A (en) | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
| US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
| US5849320A (en) | 1996-06-13 | 1998-12-15 | Novartis Corporation | Insecticidal seed coating |
| US5876739A (en) | 1996-06-13 | 1999-03-02 | Novartis Ag | Insecticidal seed coating |
| US6060594A (en) * | 1997-12-18 | 2000-05-09 | Ecogen, Inc. | Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins |
| US6023013A (en) * | 1997-12-18 | 2000-02-08 | Monsanto Company | Insect-resistant transgenic plants |
| US6121521A (en) * | 1998-04-01 | 2000-09-19 | Novartis Ag | Chimeric insecticidal protein and DNA coding therefor |
| US7253343B2 (en) * | 2003-08-28 | 2007-08-07 | Athenix Corporation | AXMI-003, a delta-endotoxin gene and methods for its use |
| IN2012DN02413A (en) | 2009-10-02 | 2015-08-21 | Syngenta Participations Ag |
-
2010
- 2010-09-27 IN IN2413DEN2012 patent/IN2012DN02413A/en unknown
- 2010-09-27 CN CN201080044606.5A patent/CN102596988B/en active Active
- 2010-09-27 RU RU2012117576A patent/RU2613778C2/en not_active IP Right Cessation
- 2010-09-27 EP EP10821081.6A patent/EP2482639B1/en not_active Not-in-force
- 2010-09-27 CA CA2775582A patent/CA2775582A1/en not_active Abandoned
- 2010-09-27 MX MX2012003658A patent/MX342640B/en active IP Right Grant
- 2010-09-27 BR BR112012009381A patent/BR112012009381A2/en not_active Application Discontinuation
- 2010-09-27 AU AU2010300850A patent/AU2010300850B2/en not_active Revoked
- 2010-09-27 UA UAA201204964A patent/UA110925C2/en unknown
- 2010-09-27 US US13/499,102 patent/US9243262B2/en active Active
- 2010-09-27 WO PCT/US2010/050369 patent/WO2011041256A2/en active Application Filing
- 2010-09-27 PH PH1/2012/500642A patent/PH12012500642A1/en unknown
- 2010-09-27 CN CN201610282033.9A patent/CN105753950B/en active Active
-
2012
- 2012-03-22 IL IL218798A patent/IL218798A0/en unknown
- 2012-03-28 ZA ZA2012/02266A patent/ZA201202266B/en unknown
- 2012-03-30 CL CL2012000799A patent/CL2012000799A1/en unknown
-
2015
- 2015-12-09 US US14/963,898 patent/US10167323B2/en active Active
- 2015-12-09 US US14/963,937 patent/US10196633B2/en active Active
-
2018
- 2018-12-04 US US16/208,856 patent/US10934330B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102596988B (en) | 2016-07-13 |
| ZA201202266B (en) | 2012-12-27 |
| US20160222374A1 (en) | 2016-08-04 |
| IL218798A0 (en) | 2012-06-28 |
| US20160201083A1 (en) | 2016-07-14 |
| MX2012003658A (en) | 2012-04-30 |
| RU2012117576A (en) | 2013-11-10 |
| PH12012500642A1 (en) | 2019-07-10 |
| EP2482639A4 (en) | 2013-05-22 |
| CN105753950B (en) | 2020-06-16 |
| US20190194644A1 (en) | 2019-06-27 |
| CL2012000799A1 (en) | 2012-10-12 |
| MX342640B (en) | 2016-10-07 |
| US9243262B2 (en) | 2016-01-26 |
| US10934330B2 (en) | 2021-03-02 |
| CN105753950A (en) | 2016-07-13 |
| AU2010300850A1 (en) | 2012-04-12 |
| EP2482639B1 (en) | 2017-08-02 |
| UA110925C2 (en) | 2016-03-10 |
| BR112012009381A2 (en) | 2017-03-01 |
| US10167323B2 (en) | 2019-01-01 |
| US20120210464A1 (en) | 2012-08-16 |
| CN102596988A (en) | 2012-07-18 |
| EP2482639A2 (en) | 2012-08-08 |
| US10196633B2 (en) | 2019-02-05 |
| AU2010300850B2 (en) | 2015-02-12 |
| WO2011041256A3 (en) | 2011-06-09 |
| RU2613778C2 (en) | 2017-03-21 |
| WO2011041256A2 (en) | 2011-04-07 |
| CA2775582A1 (en) | 2011-04-07 |
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