IN2012DN01905A - - Google Patents
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- Publication number
- IN2012DN01905A IN2012DN01905A IN1905DEN2012A IN2012DN01905A IN 2012DN01905 A IN2012DN01905 A IN 2012DN01905A IN 1905DEN2012 A IN1905DEN2012 A IN 1905DEN2012A IN 2012DN01905 A IN2012DN01905 A IN 2012DN01905A
- Authority
- IN
- India
- Prior art keywords
- salts
- mucic acid
- acid salts
- methods
- compound represented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Mucic acid salts of a compound represented by the following structural formula:(I) are disclosed. In particular, single crystalline mucic acid salts of the compound represented by structural formula (I) are characterized by a variety of properties and physical measurements. Methods of producing the mucic acid salts, using the salts to antagonize one or more aspartic proteases, and methods of treating a number of aspartic protease mediated disorders using the salts are described herein.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23186009P | 2009-08-06 | 2009-08-06 | |
PCT/US2010/044568 WO2011017533A1 (en) | 2009-08-06 | 2010-08-05 | Crystalline salts of methyl 2- ( (r) - ( 3-chloro phenyl) ( (r) -l- ( (s) -2- (methylamino) -3- ( (r) -tetrahydro-2h-pyran-3-yl) propylcarbamoyl ) |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01905A true IN2012DN01905A (en) | 2015-07-24 |
Family
ID=42797342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1905DEN2012 IN2012DN01905A (en) | 2009-08-06 | 2010-08-05 |
Country Status (8)
Country | Link |
---|---|
US (2) | US8372978B2 (en) |
EP (1) | EP2462137A1 (en) |
JP (1) | JP2013501072A (en) |
CN (1) | CN102656166A (en) |
AR (1) | AR077692A1 (en) |
IN (1) | IN2012DN01905A (en) |
TW (1) | TW201118083A (en) |
WO (1) | WO2011017533A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2007003858A (en) | 2004-10-07 | 2007-12-11 | Vitae Pharmaceuticals Inc | Diaminoalkane aspartic protease inhibitors. |
TWI411607B (en) | 2005-11-14 | 2013-10-11 | Vitae Pharmaceuticals Inc | Aspartic protease inhibitors |
CL2007002689A1 (en) | 2006-09-18 | 2008-04-18 | Vitae Pharmaceuticals Inc | COMPOUNDS DERIVED FROM PIPERIDIN-1-CARBOXAMIDA, INHIBITORS OF THE RENINE; INTERMEDIARY COMPOUNDS; PHARMACEUTICAL COMPOSITION; AND USE IN THE TREATMENT OF DISEASES SUCH AS HYPERTENSION, CARDIAC INSUFFICIENCY, CARDIAC FIBROSIS, AMONG OTHERS. |
US9896429B2 (en) | 2014-05-27 | 2018-02-20 | R.J. Reynolds Tobacco Company | Nicotine salts, co-crystals, and salt co-crystal complexes |
CN113754634A (en) | 2014-05-27 | 2021-12-07 | R.J.雷诺兹烟草公司 | Nicotine salts, co-crystals and salt co-crystal complexes |
US10508096B2 (en) | 2014-05-27 | 2019-12-17 | R.J. Reynolds Tobacco Company | Nicotine salts, co-crystals, and salt co-crystal complexes |
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-
2010
- 2010-08-03 AR ARP100102846A patent/AR077692A1/en unknown
- 2010-08-05 JP JP2012523948A patent/JP2013501072A/en active Pending
- 2010-08-05 TW TW099126051A patent/TW201118083A/en unknown
- 2010-08-05 WO PCT/US2010/044568 patent/WO2011017533A1/en active Application Filing
- 2010-08-05 IN IN1905DEN2012 patent/IN2012DN01905A/en unknown
- 2010-08-05 US US12/851,267 patent/US8372978B2/en not_active Expired - Fee Related
- 2010-08-05 CN CN2010800447250A patent/CN102656166A/en active Pending
- 2010-08-05 EP EP10742387A patent/EP2462137A1/en not_active Withdrawn
-
2013
- 2013-01-11 US US13/739,827 patent/US20130197034A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2011017533A1 (en) | 2011-02-10 |
AR077692A1 (en) | 2011-09-14 |
CN102656166A (en) | 2012-09-05 |
JP2013501072A (en) | 2013-01-10 |
US8372978B2 (en) | 2013-02-12 |
TW201118083A (en) | 2011-06-01 |
EP2462137A1 (en) | 2012-06-13 |
US20130197034A1 (en) | 2013-08-01 |
US20110098321A1 (en) | 2011-04-28 |
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