IN2012DN01414A - - Google Patents
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- Publication number
- IN2012DN01414A IN2012DN01414A IN1414DEN2012A IN2012DN01414A IN 2012DN01414 A IN2012DN01414 A IN 2012DN01414A IN 1414DEN2012 A IN1414DEN2012 A IN 1414DEN2012A IN 2012DN01414 A IN2012DN01414 A IN 2012DN01414A
- Authority
- IN
- India
- Prior art keywords
- nitroimidazooxazines
- drugs
- alone
- novel
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
The present invention relates to novel nitroimidazooxazines, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23039609P | 2009-07-31 | 2009-07-31 | |
PCT/US2010/043906 WO2011014774A1 (en) | 2009-07-31 | 2010-07-30 | Nitroimidazooxazines and their uses in anti-tubercular therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01414A true IN2012DN01414A (en) | 2015-06-05 |
Family
ID=42937154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1414DEN2012 IN2012DN01414A (en) | 2009-07-31 | 2010-07-30 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP2459571B1 (en) |
JP (1) | JP5781072B2 (en) |
KR (1) | KR101746482B1 (en) |
CN (1) | CN102753558B (en) |
AU (1) | AU2010278777B2 (en) |
BR (1) | BR112012002278A2 (en) |
CA (1) | CA2769359C (en) |
ES (1) | ES2536997T3 (en) |
IN (1) | IN2012DN01414A (en) |
NZ (1) | NZ598121A (en) |
RU (1) | RU2542988C2 (en) |
WO (1) | WO2011014774A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012141338A1 (en) * | 2011-04-15 | 2012-10-18 | Otsuka Pharmaceutical Co., Ltd. | 6,7 - dihydroimidazo [2, 1 - b] [1, 3] oxazine bactericides |
CN104059082B (en) * | 2013-03-21 | 2016-08-03 | 苏州迈泰生物技术有限公司 | Nitroimidazole heterocycle compound and the application in preparation treatment tubercular drugs thereof |
KR101682356B1 (en) | 2014-11-04 | 2016-12-06 | 한국화학연구원 | Imidazo oxazine derivatives, pharmaceutically acceptable salts thereof or optical isomer thereof and pharmaceutical composition containing the same as an active ingredient |
WO2016119706A1 (en) | 2015-01-29 | 2016-08-04 | 南京明德新药研发股份有限公司 | Anti-pulmonary tuberculosis nitroimidazole derivative |
CN108047248A (en) * | 2018-02-12 | 2018-05-18 | 丹诺医药(苏州)有限公司 | The application of oxazolidone-nitro glyoxaline coupling molecule |
CN113527331A (en) * | 2020-04-17 | 2021-10-22 | 南京长澳医药科技有限公司 | Nitroimidazole derivative and preparation method and application thereof |
CN113355439A (en) * | 2021-06-07 | 2021-09-07 | 深圳市普瑞康生物技术有限公司 | Novel combined detection method for latent infection and morbidity of mycobacterium tuberculosis |
CN114469946B (en) * | 2022-02-24 | 2023-10-24 | 首都医科大学附属北京胸科医院 | Use of delamanib as CXCL10 inhibitor |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09509963A (en) | 1994-03-08 | 1997-10-07 | アメリカン・ホーム・プロダクツ・コーポレイション | Thiazolidinedione derivatives as anti-hyperglycemic agents |
US6087358A (en) * | 1995-06-26 | 2000-07-11 | Pathogenesis Corporation | Nitro-[2,1-b]imidazopyran compounds and antibacterial uses thereof |
US5668127A (en) | 1995-06-26 | 1997-09-16 | Pathogenesis Corporation | Nitroimidazole antibacterial compounds and methods of use thereof |
TWI347946B (en) * | 2002-10-11 | 2011-09-01 | Otsuka Pharma Co Ltd | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound |
CN100497345C (en) * | 2003-10-31 | 2009-06-10 | 大塚制药株式会社 | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis |
DE602005004040T2 (en) | 2004-01-16 | 2008-12-11 | Sumitomo Chemical Co., Ltd. | Malononitrile compounds as pesticides |
TWI300409B (en) * | 2004-02-18 | 2008-09-01 | Otsuka Pharma Co Ltd | Method for producing 4-nitroimidazole compound |
WO2006043121A1 (en) * | 2004-10-20 | 2006-04-27 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
ATE529430T1 (en) * | 2005-07-28 | 2011-11-15 | Vertex Pharma | CASPASE INHIBITOR PROPHARMACIES |
US20080275035A1 (en) * | 2005-12-23 | 2008-11-06 | Jan Jiricek | Nitroimidazole Compounds |
JP5613656B2 (en) * | 2008-03-26 | 2014-10-29 | グローバル、アライアンス、フォア、ティービー、ドラッグ、ディベロップメント | Bicyclic nitroimidazoles covalently linked to substituted phenyloxazolidinones |
-
2010
- 2010-07-30 WO PCT/US2010/043906 patent/WO2011014774A1/en active Application Filing
- 2010-07-30 ES ES10742955.7T patent/ES2536997T3/en active Active
- 2010-07-30 KR KR1020127005320A patent/KR101746482B1/en active IP Right Grant
- 2010-07-30 CN CN201080041453.9A patent/CN102753558B/en not_active Expired - Fee Related
- 2010-07-30 RU RU2012107176/04A patent/RU2542988C2/en not_active IP Right Cessation
- 2010-07-30 NZ NZ598121A patent/NZ598121A/en not_active IP Right Cessation
- 2010-07-30 BR BR112012002278-4A patent/BR112012002278A2/en not_active IP Right Cessation
- 2010-07-30 JP JP2012523087A patent/JP5781072B2/en not_active Expired - Fee Related
- 2010-07-30 AU AU2010278777A patent/AU2010278777B2/en not_active Ceased
- 2010-07-30 EP EP10742955.7A patent/EP2459571B1/en not_active Not-in-force
- 2010-07-30 CA CA2769359A patent/CA2769359C/en not_active Expired - Fee Related
- 2010-07-30 IN IN1414DEN2012 patent/IN2012DN01414A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR112012002278A2 (en) | 2020-09-15 |
RU2012107176A (en) | 2013-09-10 |
JP5781072B2 (en) | 2015-09-16 |
KR20120084713A (en) | 2012-07-30 |
ES2536997T3 (en) | 2015-06-01 |
EP2459571B1 (en) | 2015-03-11 |
AU2010278777A1 (en) | 2012-03-01 |
CN102753558A (en) | 2012-10-24 |
KR101746482B1 (en) | 2017-06-27 |
NZ598121A (en) | 2013-04-26 |
EP2459571A1 (en) | 2012-06-06 |
CA2769359C (en) | 2017-03-07 |
AU2010278777B2 (en) | 2015-05-07 |
WO2011014774A1 (en) | 2011-02-03 |
JP2013500996A (en) | 2013-01-10 |
CA2769359A1 (en) | 2011-02-03 |
CN102753558B (en) | 2014-10-15 |
RU2542988C2 (en) | 2015-02-27 |
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