IN2012DN00570A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN00570A IN2012DN00570A IN570DEN2012A IN2012DN00570A IN 2012DN00570 A IN2012DN00570 A IN 2012DN00570A IN 570DEN2012 A IN570DEN2012 A IN 570DEN2012A IN 2012DN00570 A IN2012DN00570 A IN 2012DN00570A
- Authority
- IN
- India
- Prior art keywords
- biodegradable polymer
- compositions
- present
- matrix
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Abstract
The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block- co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22528909P | 2009-07-14 | 2009-07-14 | |
PCT/IL2010/000563 WO2011007353A1 (en) | 2009-07-14 | 2010-07-14 | Sustained-release drug carrier composition |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00570A true IN2012DN00570A (en) | 2015-06-12 |
Family
ID=43448999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN570DEN2012 IN2012DN00570A (en) | 2009-07-14 | 2010-07-14 |
Country Status (9)
Country | Link |
---|---|
US (2) | US8992979B2 (en) |
EP (1) | EP2453877B1 (en) |
JP (1) | JP5738856B2 (en) |
CN (2) | CN105126179B (en) |
AU (1) | AU2010272167B2 (en) |
CA (1) | CA2767973C (en) |
ES (1) | ES2732149T3 (en) |
IN (1) | IN2012DN00570A (en) |
WO (1) | WO2011007353A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2630805T3 (en) | 2008-07-14 | 2017-08-24 | Polypid Ltd. | Sustained release drug vehicle composition |
US8795726B2 (en) | 2010-01-19 | 2014-08-05 | Polypid Ltd. | Sustained-release nucleic acid matrix compositions |
EP2736492A4 (en) * | 2011-07-27 | 2015-06-17 | Polypid Ltd | Matrix compositions for controlled release of peptide and polypeptide molecules |
JP5900909B2 (en) * | 2012-03-27 | 2016-04-06 | 国立大学法人名古屋大学 | Three-dimensional structure made from material containing polyhydroxyalkanoate and kit for preparing bone filler |
US9173976B2 (en) * | 2012-08-02 | 2015-11-03 | Polypid Ltd. | Compositions and methods for the treatment of bone voids and open fractures |
CA2885334C (en) * | 2012-11-14 | 2016-03-08 | Orthopaedic Innovation Centre Inc. | Antimicrobial articles produced by additive manufacturing |
US9775853B2 (en) | 2013-03-15 | 2017-10-03 | Biomet Manufacturing, Llc. | Hemostatic compositions and methods |
TW201618783A (en) | 2014-08-07 | 2016-06-01 | 艾森塔製藥公司 | Methods of treating cancers, immune and autoimmune diseases, and inflammatory diseases based on BTK occupancy and BTK resynthesis rate |
JP6526400B2 (en) * | 2014-09-11 | 2019-06-05 | サンスター株式会社 | Oral composition |
JP2017531461A (en) * | 2014-10-02 | 2017-10-26 | ポリピッド リミテッド | Treatment of peri-implantitis |
EA201790383A1 (en) * | 2014-10-02 | 2017-09-29 | Полипид Лтд. | COMPOSITIONS AND METHODS OF TREATMENT AND PREVENTION OF INFECTIONS OF SURGERY INTERVENTION |
WO2017139357A1 (en) * | 2016-02-08 | 2017-08-17 | Orbusneich Medical, Inc. | Drug eluting balloon |
US10792477B2 (en) | 2016-02-08 | 2020-10-06 | Orbusneich Medical Pte. Ltd. | Drug eluting balloon |
CN106146761A (en) * | 2016-06-03 | 2016-11-23 | 西北大学 | The nano-micelle of a kind of amphipathic multifunctional polymer and preparation thereof and application |
JP7102423B2 (en) * | 2017-02-16 | 2022-07-19 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッド | Liposomal drug delivery vehicle |
US11690807B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
SG11202005949UA (en) | 2018-05-24 | 2020-07-29 | Celanese Eva Performance Polymers Corp | Implantable device for sustained release of a macromolecular drug compound |
CN113081482B (en) * | 2021-04-23 | 2024-02-27 | 柏为(武汉)医疗科技股份有限公司 | Middle ear anti-adhesion membrane and preparation method thereof |
CN113702647B (en) * | 2021-08-31 | 2024-03-15 | 普十生物科技(北京)有限公司 | Human growth differentiation factor 15 instant detection kit, preparation method and application thereof |
Family Cites Families (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4522803A (en) | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
US4882167A (en) | 1983-05-31 | 1989-11-21 | Jang Choong Gook | Dry direct compression compositions for controlled release dosage forms |
US4578384A (en) | 1984-02-15 | 1986-03-25 | The United States Of America As Represented By The Secretary Of The Army | Polylactic-polyglycolic acids combined with an acidic phospholipid-lysozyme complex for healing osseous tissue |
JPS6163613A (en) | 1984-09-04 | 1986-04-01 | Mitsui Toatsu Chem Inc | Sustained release preparation |
US5043166A (en) | 1987-01-09 | 1991-08-27 | Hadasit Medical Research, Inc. | Liposome/anthraquinone drug composition and method |
IL91664A (en) | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
ES2085465T3 (en) | 1989-11-13 | 1996-06-01 | Abraham J Domb | LIPOESFERAS FOR THE CONTROLLED ADMINISTRATION OF SUBSTANCES. |
US6120805A (en) | 1990-04-06 | 2000-09-19 | Rhone-Poulenc Rorer Sa | Microspheres, process for their preparation and their use |
US5922340A (en) | 1992-09-10 | 1999-07-13 | Children's Medical Center Corporation | High load formulations and methods for providing prolonged local anesthesia |
US6180134B1 (en) | 1993-03-23 | 2001-01-30 | Sequus Pharmaceuticals, Inc. | Enhanced ciruclation effector composition and method |
CA2190121A1 (en) | 1994-03-15 | 1995-09-21 | Edith Mathiowitz | Polymeric gene delivery system |
US6156337A (en) | 1994-07-08 | 2000-12-05 | Opperbas Holding B.V. | Method for high loading of vesicles with biopolymeric substances |
US6333021B1 (en) | 1994-11-22 | 2001-12-25 | Bracco Research S.A. | Microcapsules, method of making and their use |
US6040295A (en) | 1995-01-13 | 2000-03-21 | Genemedicine, Inc. | Formulated nucleic acid compositions and methods of administering the same for gene therapy |
US5919480A (en) | 1996-06-24 | 1999-07-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal influenza vaccine composition and method |
US5837221A (en) | 1996-07-29 | 1998-11-17 | Acusphere, Inc. | Polymer-lipid microencapsulated gases for use as imaging agents |
WO1998007412A1 (en) | 1996-08-21 | 1998-02-26 | Alkermes Controlled Therapeutics, Inc. | Controlled release microparticles with a hydrophobic material |
DE69737915T2 (en) | 1996-09-11 | 2008-03-13 | Bristol-Myers Squibb Medical Imaging, Inc. | Method of diagnostic imaging of the kidney region using a contrast agent and a vasodilator |
US6048551A (en) | 1997-03-27 | 2000-04-11 | Hilfinger; John M. | Microsphere encapsulation of gene transfer vectors |
IL129951A0 (en) | 1997-07-02 | 2000-02-29 | Euro Celtique Sa | Prolonged anesthesia in joints and body spaces |
US6287587B2 (en) | 1997-07-15 | 2001-09-11 | Takeda Chemical Industries, Ltd. | Process for producing sustained-release preparation by in-water drying |
US6787132B1 (en) | 1997-12-04 | 2004-09-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Combined chemo-immunotherapy with liposomal drugs and cytokines |
CA2329768C (en) | 1998-04-27 | 2008-06-10 | Opperbas Holding B.V. | Pharmaceutical composition comprising factor viii and neutral liposomes |
US6423345B2 (en) | 1998-04-30 | 2002-07-23 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
ATE428371T1 (en) | 1998-07-17 | 2009-05-15 | Pacira Pharmaceuticals Inc | BIODEGRADABLE ARRANGEMENTS FOR THE CONTROLLED RELEASE OF ENCLOSED SUBSTANCES |
CA2340118C (en) | 1998-08-12 | 2009-01-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal bupivacaine compositions prepared using an ammonium sulfate gradient |
US6153217A (en) | 1999-01-22 | 2000-11-28 | Biodelivery Sciences, Inc. | Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents |
US6083482A (en) | 1999-05-11 | 2000-07-04 | Icn Pharmaceuticals, Inc. | Conformationally locked nucleosides and oligonucleotides |
AU5624400A (en) | 1999-06-18 | 2001-01-09 | Collaborative Group, Ltd., The | Hyaluronic acid film and matrix for sustained gene transfer |
DE10001172A1 (en) | 2000-01-13 | 2001-07-26 | Max Planck Gesellschaft | Templating solid particles with polymer multilayers |
US6967028B2 (en) | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
US20030161809A1 (en) * | 2000-10-02 | 2003-08-28 | Houston L. L. | Compositions and methods for the transport of biologically active agents across cellular barriers |
FI20010540A0 (en) | 2001-03-16 | 2001-03-16 | Yli Urpo Antti | Composite for the correction of defects in soft and hard tissue and the use of said composite |
MXPA04002980A (en) * | 2001-09-28 | 2005-06-20 | Johnson & Johnson | Dosage forms having an inner core and outer shell with different shapes. |
TWI226249B (en) | 2001-12-19 | 2005-01-11 | Ind Tech Res Inst | Biodegradable composite matrix for enhancing angiogenesis |
EP3100719A3 (en) | 2002-05-15 | 2017-02-22 | California Pacific Medical Center | Delivery of nucleic acid-like compounds |
US20040062778A1 (en) * | 2002-09-26 | 2004-04-01 | Adi Shefer | Surface dissolution and/or bulk erosion controlled release compositions and devices |
TWI367113B (en) * | 2003-02-12 | 2012-07-01 | Syncera Inc | Random and non-random alkylene oxide polymer alloy compositions |
GB0305941D0 (en) | 2003-03-14 | 2003-04-23 | Camurus Ab | Composition |
CA2521916C (en) | 2003-04-10 | 2013-06-25 | Teijin Limited | Biodegradable film having a honeycomb structure for the prevention of postoperative tissue adhesion |
US20040247624A1 (en) * | 2003-06-05 | 2004-12-09 | Unger Evan Charles | Methods of making pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
US20060188573A1 (en) * | 2003-06-10 | 2006-08-24 | Anna Imberg | Composite materials and particles |
US20050249697A1 (en) | 2003-09-24 | 2005-11-10 | Uhrich Kathryn E | Compositions and methods for the inhibition of bone growth and resorption |
EP1693075B1 (en) | 2003-11-21 | 2012-10-03 | Teijin Limited | Substrate for tissue regeneration |
CA2553426A1 (en) | 2004-01-15 | 2005-08-04 | Alza Corporation | Liposome composition for delivery of therapeutic agents |
US8277831B2 (en) * | 2004-02-17 | 2012-10-02 | Advanced Technologies And Regenerative Medicine, Llc. | Drug-enhanced adhesion prevention |
US7744644B2 (en) | 2004-03-19 | 2010-06-29 | Boston Scientific Scimed, Inc. | Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release |
DE102004025495A1 (en) * | 2004-05-21 | 2005-12-15 | Dr. Suwelack Skin & Health Care Ag | Process for the production of alginate-containing porous moldings |
NZ551990A (en) | 2004-06-04 | 2011-01-28 | Camurus Ab | Liquid depot formulations |
US20050287180A1 (en) * | 2004-06-15 | 2005-12-29 | Chen Andrew X | Phospholipid compositions and methods for their preparation and use |
US7906140B2 (en) | 2004-06-17 | 2011-03-15 | Virun, Inc. | Compositions for mucosal delivery of agents |
KR20070054644A (en) | 2004-07-26 | 2007-05-29 | 액테리온 파마슈티칼 리미티드 | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
US8790672B2 (en) * | 2005-02-22 | 2014-07-29 | Nina M. Lamba-Kohli | Generation of antimicrobial surfaces using dendrimer biocides |
JP2008539260A (en) | 2005-04-25 | 2008-11-13 | アムジエン・インコーポレーテツド | Biodegradable ptide sustained-release composition containing porogen |
US20070141134A1 (en) | 2005-12-16 | 2007-06-21 | Kosak Matthew K | Shielded micelles for polynucleotide delivery |
US20090318355A1 (en) | 2006-02-15 | 2009-12-24 | Chen Thomas T | Compositions and methods for promoting tissue repair and wound healing |
ES2776100T3 (en) | 2006-03-31 | 2020-07-29 | Massachusetts Inst Technology | System for targeted delivery of therapeutic agents |
US8703167B2 (en) * | 2006-06-05 | 2014-04-22 | Advanced Cardiovascular Systems, Inc. | Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug |
CA2656179A1 (en) * | 2006-06-21 | 2007-12-27 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
CN101209243B (en) * | 2006-12-29 | 2010-12-08 | 石药集团中奇制药技术(石家庄)有限公司 | Liposome medicament and preparation thereof |
RU2428186C2 (en) * | 2007-03-02 | 2011-09-10 | Теика Фармасьютикал Ко., Лтд. | Medical composition for percutaneous absorbtion, product keeping medical composition, and preparation for percutaneous absorbtion containing it |
WO2008124634A1 (en) | 2007-04-04 | 2008-10-16 | Massachusetts Institute Of Technology | Polymer-encapsulated reverse micelles |
WO2009006311A2 (en) | 2007-06-29 | 2009-01-08 | Wisconsin Alumni Research Foundation | Structuring effect of cholesterol in peg-phospholipid micelles, drug delivery of amphotericin b, and combination antifungals |
US20090110713A1 (en) | 2007-10-31 | 2009-04-30 | Florencia Lim | Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices |
AU2008325122A1 (en) | 2007-11-09 | 2009-05-14 | Northeastern University | Self-assembling micelle-like nanoparticles for systemic gene delivery |
WO2009110939A2 (en) | 2007-12-10 | 2009-09-11 | Massachusetts Institute Of Technology | Drug delivery system for pharmaceuticals and radiation |
US8128983B2 (en) | 2008-04-11 | 2012-03-06 | Abbott Cardiovascular Systems Inc. | Coating comprising poly(ethylene glycol)-poly(lactide-glycolide-caprolactone) interpenetrating network |
AU2009238175C1 (en) | 2008-04-15 | 2023-11-30 | Arbutus Biopharma Corporation | Novel lipid formulations for nucleic acid delivery |
ES2630805T3 (en) | 2008-07-14 | 2017-08-24 | Polypid Ltd. | Sustained release drug vehicle composition |
US9012622B2 (en) | 2008-12-31 | 2015-04-21 | Patrick Y. Lu | Compositions and methods using siRNA molecules and siRNA cocktails for the treatment of breast cancer |
CN102985548B (en) | 2009-05-16 | 2016-10-26 | 崔坤元 | For deliver treatment molecule comprise cationic amphiphilic thing and the compositions of auxiliary lipid |
US8795726B2 (en) | 2010-01-19 | 2014-08-05 | Polypid Ltd. | Sustained-release nucleic acid matrix compositions |
CA2861848A1 (en) * | 2012-01-10 | 2013-06-28 | Monika Mujkic | Renewable fatty acid waxes and methods of making |
-
2010
- 2010-07-14 WO PCT/IL2010/000563 patent/WO2011007353A1/en active Application Filing
- 2010-07-14 ES ES10799520T patent/ES2732149T3/en active Active
- 2010-07-14 CN CN201510441212.8A patent/CN105126179B/en active Active
- 2010-07-14 IN IN570DEN2012 patent/IN2012DN00570A/en unknown
- 2010-07-14 AU AU2010272167A patent/AU2010272167B2/en active Active
- 2010-07-14 CN CN201080034537.XA patent/CN102470105B/en active Active
- 2010-07-14 JP JP2012520148A patent/JP5738856B2/en active Active
- 2010-07-14 EP EP10799520.1A patent/EP2453877B1/en active Active
- 2010-07-14 US US13/383,893 patent/US8992979B2/en active Active
- 2010-07-14 CA CA2767973A patent/CA2767973C/en active Active
-
2015
- 2015-02-17 US US14/623,528 patent/US10463617B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8992979B2 (en) | 2015-03-31 |
JP2012533334A (en) | 2012-12-27 |
US20150174073A1 (en) | 2015-06-25 |
US20120114756A1 (en) | 2012-05-10 |
US10463617B2 (en) | 2019-11-05 |
WO2011007353A1 (en) | 2011-01-20 |
CA2767973A1 (en) | 2011-01-20 |
JP5738856B2 (en) | 2015-06-24 |
EP2453877A4 (en) | 2013-05-29 |
CN102470105A (en) | 2012-05-23 |
CN105126179A (en) | 2015-12-09 |
AU2010272167A1 (en) | 2012-02-02 |
CN102470105B (en) | 2015-07-29 |
ES2732149T3 (en) | 2019-11-20 |
EP2453877A1 (en) | 2012-05-23 |
CN105126179B (en) | 2018-09-25 |
AU2010272167B2 (en) | 2016-11-17 |
CA2767973C (en) | 2019-06-18 |
EP2453877B1 (en) | 2019-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2012DN00570A (en) | ||
PH12021550756A1 (en) | Compositions and methods for treating and/or preventing cardiovascular disease | |
MX2010003299A (en) | Micromirs. | |
BRPI0917017B8 (en) | s-nitrosoglutathione reductase pyrrole inhibitors as therapeutic agents | |
IL211541A0 (en) | Co-crystal compositions, methods of producing the same and uses thereof | |
GB2488075B (en) | Polymer composition, swellable composition comprising the polymer composition, and articles including the swellable composition | |
ZA201008398B (en) | An electrochemically active composition,methods of making,and uses thereof | |
EP2305209A3 (en) | Composition comprising a polyol,a sugar silicone surfactant and an oil-soluble high carbon polar modified polymer | |
EP2569330A4 (en) | Chlorotoxin variants, conjugates, and methods for their use | |
WO2010017215A3 (en) | Biodegradable microspheres and methods of use thereof | |
WO2010125475A3 (en) | Sustained release formulations comprising gnrh analogues | |
PL2513023T3 (en) | Compositions and uses of cis-1,1,1,4,4,4-hexafluoro-2-butene | |
WO2008087215A3 (en) | Partially bioabsorbable implant | |
WO2011003902A3 (en) | Multimodal visible polymer embolization material | |
EP2488023A4 (en) | Antimicrobial composition | |
EP2395048A3 (en) | Polymers compositions including an antioxidant | |
BRPI1011188A2 (en) | dermal release compositions comprising calcium phosphate-active agent particle complexes and methods for using them. | |
MX2011012504A (en) | Pyrazinylpyrazoles. | |
UA86731C2 (en) | Divisible galenic form of the modified drug release | |
UA103025C2 (en) | Solid pharmaceutical formulation with delayed release | |
MX2012007365A (en) | Slow release pharmaceutical compositions of iloperidone. | |
IN2012DN03404A (en) | ||
WO2011035013A3 (en) | Implant devices that differ by release profile and methods of making and using same | |
MX2011006721A (en) | Pharmaceutical formulation of nanonised fenofibrate. | |
MX2014006574A (en) | Acamprosate formulations, methods of using the same, and combinations comprising the same. |