IN2012DN00546A - - Google Patents
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- Publication number
- IN2012DN00546A IN2012DN00546A IN546DEN2012A IN2012DN00546A IN 2012DN00546 A IN2012DN00546 A IN 2012DN00546A IN 546DEN2012 A IN546DEN2012 A IN 546DEN2012A IN 2012DN00546 A IN2012DN00546 A IN 2012DN00546A
- Authority
- IN
- India
- Prior art keywords
- derivatives
- pharmaceutical compositions
- tazarotene
- making
- subject matter
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The presently described subject matter relates to new derivatives of tazarotene that also exhibit retinoid activity, pharmaceutical compositions comprising the derivatives, method of treating skin disorders with the pharmaceutical compositions, and process of making the derivatives.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21379409P | 2009-07-16 | 2009-07-16 | |
US27225709P | 2009-09-04 | 2009-09-04 | |
PCT/US2010/042225 WO2011009023A1 (en) | 2009-07-16 | 2010-07-16 | Tazarotene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00546A true IN2012DN00546A (en) | 2015-06-12 |
Family
ID=43449815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN546DEN2012 IN2012DN00546A (en) | 2009-07-16 | 2010-07-16 |
Country Status (16)
Country | Link |
---|---|
US (3) | US20120115909A1 (en) |
EP (1) | EP2453746A4 (en) |
JP (1) | JP5635090B2 (en) |
KR (1) | KR101536806B1 (en) |
CN (1) | CN102595892B (en) |
AU (1) | AU2010273261B2 (en) |
BR (1) | BR112012001680A2 (en) |
CA (1) | CA2768015C (en) |
EA (1) | EA022322B1 (en) |
IL (1) | IL217519A (en) |
IN (1) | IN2012DN00546A (en) |
MX (1) | MX2012000768A (en) |
NZ (1) | NZ598240A (en) |
SG (1) | SG177579A1 (en) |
WO (1) | WO2011009023A1 (en) |
ZA (1) | ZA201200253B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201105050D0 (en) * | 2011-03-25 | 2011-05-11 | Iiaa Ltd | Pharmaceutical agent |
DK2723347T3 (en) * | 2011-06-24 | 2019-11-18 | Gri Bio Inc | Prevention and treatment of inflammatory conditions |
CN106918676B (en) * | 2015-12-24 | 2020-08-11 | 重庆华邦制药有限公司 | Method for separating and measuring contents of two drugs in tazarotene betamethasone cream and related substances |
WO2017152725A1 (en) * | 2016-03-11 | 2017-09-14 | 中国科学院上海有机化学研究所 | Retinoid compound, preparation method therefor, intermediates thereof and application thereof |
CN107176945B (en) * | 2016-03-11 | 2021-06-08 | 中国科学院上海有机化学研究所 | Retinoid compound, preparation method, intermediate and application thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4801593A (en) * | 1979-09-13 | 1989-01-31 | Burroughs Wellcome Co. | Chemotherapeutic agents |
US5399561A (en) * | 1989-09-19 | 1995-03-21 | Allergan, Inc. | Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-oxochromanyl, 2-oxothiochromanyl or 2-oxo-1,2,3,4-tetrahydro-quinolinyl group having retinoid-like biological activity |
US5272156A (en) | 1989-09-19 | 1993-12-21 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
US5162546A (en) | 1989-09-19 | 1992-11-10 | Allergan, Inc. | Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
US5183827A (en) * | 1989-09-19 | 1993-02-02 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
US4980369A (en) | 1989-09-19 | 1990-12-25 | Allergan, Inc. | Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity |
US5045551A (en) | 1989-09-19 | 1991-09-03 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
HUT63405A (en) | 1990-10-09 | 1993-08-30 | Allergan Inc | Process for producing acetylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and having retinoid-like activity, as well as pharmaceutical compositions comprising same as active ingredient |
ATE144258T1 (en) | 1991-02-13 | 1996-11-15 | Allergan Inc | 7-PHENYLETHYNYL-SUBSTITUTED CHROMANES AND THIOCHROMANES WITH RETINOID-LIKE BIOLOGICAL ACTIVITY |
WO1992017471A1 (en) | 1991-03-26 | 1992-10-15 | Allergan, Inc. | Chromans and thiochromans with heteroarylethynyl substituents at the 7-position having retinoid-like biological activity |
CN1133422C (en) * | 1997-07-08 | 2004-01-07 | 科斯莫弗姆有限公司 | Topical application of combination of benzoyl peroxide and second active ingredient |
DK1100490T3 (en) * | 1998-07-28 | 2007-04-10 | Susan Bershad | Treatment with short contact time of acne and photo aging with topical retinoids |
US6048902A (en) * | 1999-02-12 | 2000-04-11 | Lebwohl; Mark G. | Short contact treatment of psoriasis with topical retinoids |
FR2830449B1 (en) * | 2001-10-05 | 2004-04-23 | Fabre Pierre Dermo Cosmetique | USE OF TAZAROTENE FOR THE PREPARATION OF A NAIL VARNISH FOR THE TREATMENT AND / OR PREVENTION OF PSORIASIS AND A NAIL VARNISH CONTAINING IT |
CN1210041C (en) * | 2003-09-29 | 2005-07-13 | 中国医学科学院皮肤病研究所 | Complex external medicine for treating acne |
ITMI20050357A1 (en) * | 2005-03-08 | 2006-09-09 | Solmag S P A | TAZAROTENE PREPARATION PROCEDURE |
AR054805A1 (en) * | 2005-06-29 | 2007-07-18 | Stiefel Laboratories | TOPICAL COMPOSITIONS FOR SKIN TREATMENT |
US9107844B2 (en) * | 2006-02-03 | 2015-08-18 | Stiefel Laboratories Inc. | Topical skin treating compositions |
MXPA06008988A (en) * | 2006-08-08 | 2008-02-07 | Fernando Ahumada Ayala | Topical antiacne preparations containing retinoid (tazarotene or adapalene), antibiotic (clindamycin phosphate) and/or keratolytic (miscrosponged benzoyl peroxide). |
ES2912051T3 (en) * | 2007-02-01 | 2022-05-24 | Sol Gel Tech Ltd | Compositions for topical application comprising a peroxide and retinoid |
-
2010
- 2010-07-16 BR BRBR112012001680-6A patent/BR112012001680A2/en not_active IP Right Cessation
- 2010-07-16 SG SG2012001509A patent/SG177579A1/en unknown
- 2010-07-16 WO PCT/US2010/042225 patent/WO2011009023A1/en active Application Filing
- 2010-07-16 MX MX2012000768A patent/MX2012000768A/en active IP Right Grant
- 2010-07-16 AU AU2010273261A patent/AU2010273261B2/en not_active Ceased
- 2010-07-16 EA EA201270176A patent/EA022322B1/en not_active IP Right Cessation
- 2010-07-16 CA CA2768015A patent/CA2768015C/en not_active Expired - Fee Related
- 2010-07-16 CN CN201080041425.7A patent/CN102595892B/en not_active Expired - Fee Related
- 2010-07-16 EP EP10800590.1A patent/EP2453746A4/en not_active Withdrawn
- 2010-07-16 NZ NZ598240A patent/NZ598240A/en not_active IP Right Cessation
- 2010-07-16 IN IN546DEN2012 patent/IN2012DN00546A/en unknown
- 2010-07-16 JP JP2012520808A patent/JP5635090B2/en not_active Expired - Fee Related
- 2010-07-16 KR KR1020127003938A patent/KR101536806B1/en not_active IP Right Cessation
- 2010-07-16 US US13/383,869 patent/US20120115909A1/en not_active Abandoned
-
2012
- 2012-01-12 IL IL217519A patent/IL217519A/en not_active IP Right Cessation
- 2012-01-12 ZA ZA2012/00253A patent/ZA201200253B/en unknown
-
2014
- 2014-08-20 US US14/463,985 patent/US9062037B2/en not_active Expired - Fee Related
- 2014-08-20 US US14/464,060 patent/US20140357669A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN102595892B (en) | 2014-09-10 |
WO2011009023A1 (en) | 2011-01-20 |
AU2010273261A1 (en) | 2012-02-02 |
CN102595892A (en) | 2012-07-18 |
KR20120056821A (en) | 2012-06-04 |
JP5635090B2 (en) | 2014-12-03 |
KR101536806B1 (en) | 2015-07-14 |
EP2453746A4 (en) | 2013-04-24 |
AU2010273261B2 (en) | 2013-07-25 |
US20140357672A1 (en) | 2014-12-04 |
US20120115909A1 (en) | 2012-05-10 |
BR112012001680A2 (en) | 2015-09-01 |
US9062037B2 (en) | 2015-06-23 |
CA2768015C (en) | 2016-03-15 |
US20140357669A1 (en) | 2014-12-04 |
IL217519A0 (en) | 2012-02-29 |
EA022322B1 (en) | 2015-12-30 |
IL217519A (en) | 2015-06-30 |
EA201270176A1 (en) | 2012-08-30 |
ZA201200253B (en) | 2013-05-29 |
SG177579A1 (en) | 2012-02-28 |
MX2012000768A (en) | 2012-02-13 |
CA2768015A1 (en) | 2011-01-20 |
NZ598240A (en) | 2013-10-25 |
JP2012533564A (en) | 2012-12-27 |
EP2453746A1 (en) | 2012-05-23 |
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