IN2012DE00442AIN442DE2012AIN2012DE00442AIN 2012DE00442 AIN2012DE00442 AIN 2012DE00442AIN 442DE2012 AIN442DE2012 AIN 442DE2012AIN 2012DE00442 AIN2012DE00442 AIN 2012DE00442A
Authority
IN
India
Prior art keywords
interferon gamma
release
testing
blood cells
infectious disease
Prior art date
Application number
Inventor
Talluri; Sekhar
Rathindranath; Sinha
Original Assignee
Gitam University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gitam UniversityfiledCriticalGitam University
Priority to IN442DE2012priorityCriticalpatent/IN2012DE00442A/en
Publication of IN2012DE00442ApublicationCriticalpatent/IN2012DE00442A/en
The present invention relates to an immunochromatographic device which enables the detection of an infectious disease by testing for the release of interferon gamma from the blood cells of individuals exposed to the microbes responsible for causing the infectious disease. Particularly, the invention provides an immunochromatographic device which detects tuberculosis by testing for the release of interferon gamma from the blood cells of infected individuals. The said device comprises of a sample pad, a detection pad, multiple reagent reservoirs and multiple fluidic paths that can be activated at specified times under user control, as per the requirements of the assay. The device is designed to combine the advantages of high sensitivity and selectivity associated with conventional interferon gamma release assays and the ease of use of devices based on immunochromatography. The device is suitable for point-of-care diagnostics in locations that do not have access to standard clinical laboratory equipment.