IN2012DE00263AIN263DE2012AIN2012DE00263AIN 2012DE00263 AIN2012DE00263 AIN 2012DE00263AIN 263DE2012 AIN263DE2012 AIN 263DE2012AIN 2012DE00263 AIN2012DE00263 AIN 2012DE00263A
Authority
IN
India
Prior art keywords
diethylpentane
diamine
chloroquinolin
formula
antipasisitic
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Application number
Inventor
Seturam Bandhacharya Katti
Wahajul Haq
Kumkum Srivastava
Sunil Kumar Puri
Manish Sinha
Awaksh Soni
Rajeev Kumar Srivastava
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Council Scient Ind Res
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Application filed by Council Scient Ind ResfiledCriticalCouncil Scient Ind Res
Priority to IN263DE2012priorityCriticalpatent/IN2012DE00263A/en
Publication of IN2012DE00263ApublicationCriticalpatent/IN2012DE00263A/en
Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Abstract
The present invention relates to the development of process for the preparation of to C4 (R)-and (S)-N1,N1-diethylpentane-1,4-diamine and its use for the synthesis of C4 (R) and (S) chloroquine of formula-1 ((R)-N4-(7-chloroquinolin-4-yl)-N1,N1- diethylpentane 1,4-diamine and (S)-N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine) as well as their derivatives of the formula 2 as potential amtimalarial and antipasisitic agents.