IN2012DE00082A - - Google Patents

Info

Publication number
IN2012DE00082A
IN2012DE00082A IN82DE2012A IN2012DE00082A IN 2012DE00082 A IN2012DE00082 A IN 2012DE00082A IN 82DE2012 A IN82DE2012 A IN 82DE2012A IN 2012DE00082 A IN2012DE00082 A IN 2012DE00082A
Authority
IN
India
Prior art keywords
synthesis
relates
hiv protease
synazido
sequinavirvia
Prior art date
Application number
Other languages
English (en)
Inventor
Khanderao Gadakh Sunita
Santhosh Rekula Reddy
Sudalai Arumugam
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Priority to IN82DE2012 priority Critical patent/IN2012DE00082A/en
Priority to PCT/IN2013/000021 priority patent/WO2013105118A1/en
Priority to US14/371,466 priority patent/US9233943B2/en
Publication of IN2012DE00082A publication Critical patent/IN2012DE00082A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/02Synthesis of the oxirane ring
    • C07D301/03Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
    • C07D301/14Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • C07C247/02Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/04Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/02Synthesis of the oxirane ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IN82DE2012 2012-01-10 2013-01-10 IN2012DE00082A (US06559137-20030506-C00182.png)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IN82DE2012 IN2012DE00082A (US06559137-20030506-C00182.png) 2012-01-10 2013-01-10
PCT/IN2013/000021 WO2013105118A1 (en) 2012-01-10 2013-01-10 A process for synthesis of syn azido epoxide and its use as intermediate the synthesis of amprenavir & saquinavir
US14/371,466 US9233943B2 (en) 2012-01-10 2013-01-10 Process for synthesis of syn azido epdxide and its use as intermediate for the synthesis of amprenavir and saquinavir

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN82DE2012 IN2012DE00082A (US06559137-20030506-C00182.png) 2012-01-10 2013-01-10

Publications (1)

Publication Number Publication Date
IN2012DE00082A true IN2012DE00082A (US06559137-20030506-C00182.png) 2015-05-01

Family

ID=47750776

Family Applications (1)

Application Number Title Priority Date Filing Date
IN82DE2012 IN2012DE00082A (US06559137-20030506-C00182.png) 2012-01-10 2013-01-10

Country Status (3)

Country Link
US (1) US9233943B2 (US06559137-20030506-C00182.png)
IN (1) IN2012DE00082A (US06559137-20030506-C00182.png)
WO (1) WO2013105118A1 (US06559137-20030506-C00182.png)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11311526B2 (en) * 2016-03-31 2022-04-26 Georgetown University Radiation mitigator and method of use thereof
CN108486647B (zh) * 2018-05-24 2024-08-06 上海夕心半导体科技有限公司 提拉法CeAlO3晶体生长装置及其控制方法
EP3587382A1 (en) 2018-06-28 2020-01-01 Rheinische Friedrich-Wilhelms-Universität Bonn Click-mass spectrometry of alkyne-labeled compounds
CN111233794A (zh) * 2020-03-27 2020-06-05 江巨东 一种安普那韦的精制方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927913D0 (en) 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
WO1999067254A2 (en) 1998-06-23 1999-12-29 The United States Of America Represented By The Secretary, Department Of Health And Human Services Multi-drug resistant retroviral protease inhibitors and use thereof
WO1999067417A2 (en) 1998-06-23 1999-12-29 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Fitness assay and associated methods
GB9815567D0 (en) 1998-07-18 1998-09-16 Glaxo Group Ltd Antiviral compound
AU6329599A (en) 1998-09-28 2000-04-17 Glaxo Group Limited Antiviral combinations comprising (s)-2-ethyl -7-fluoro -3-oxo-3, 4-dihydro -2h-quinoxaline -1-carboxylic acid isopropyl ester

Also Published As

Publication number Publication date
WO2013105118A8 (en) 2013-10-10
US20150011782A1 (en) 2015-01-08
WO2013105118A1 (en) 2013-07-18
US9233943B2 (en) 2016-01-12

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